Imaging single events at the cell membrane Export

@article{citeulike:3206352, abstract = {The ability to sense and respond to the environment is a hallmark of living systems. These processes occur at the levels of the organism, cells and individual molecules. Sensing of extracellular changes could result in a structural or chemical alteration in a molecule, which could in turn trigger a cascade of intracellular signals or regulated trafficking of molecules at the cell surface. These and other such processes allow cells to sense and respond to environmental changes. Often, these changes and the responses to them are spatially and/or temporally localized, and visualization of such events necessitates the use of high-resolution imaging approaches. Here we discuss optical imaging approaches and tools for imaging individual events at the cell surface with improved speed and resolution.}, address = {The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA.}, author = {Jaiswal, Jyoti K. and Simon, Sanford M.}, citeulike-article-id = {3206352}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nchembio855}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nchembio855}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/17235347}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=17235347}, doi = {10.1038/nchembio855}, issn = {1552-4450}, journal = {Nat Chem Biol}, keywords = {endocytosis, membrane-diffusion, review, single-molecule, tirf}, month = {February}, number = {2}, pages = {92--98}, posted-at = {2008-09-08 16:16:02}, priority = {0}, publisher = {Nature Publishing Group}, title = {Imaging single events at the cell membrane}, url = {http://dx.doi.org/10.1038/nchembio855}, volume = {3}, year = {2007} }

TY - JOUR ID - citeulike:3206352 L3 - citeulike-article-id:3206352 N2 - The ability to sense and respond to the environment is a hallmark of living systems. These processes occur at the levels of the organism, cells and individual molecules. Sensing of extracellular changes could result in a structural or chemical alteration in a molecule, which could in turn trigger a cascade of intracellular signals or regulated trafficking of molecules at the cell surface. These and other such processes allow cells to sense and respond to environmental changes. Often, these changes and the responses to them are spatially and/or temporally localized, and visualization of such events necessitates the use of high-resolution imaging approaches. Here we discuss optical imaging approaches and tools for imaging individual events at the cell surface with improved speed and resolution. IS - 2 JF - Nat Chem Biol SN - 1552-4450 AD - The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA. EP - 98 TI - Imaging single events at the cell membrane PB - Nature Publishing Group VL - 3 SP - 92 KW - endocytosis KW - membrane-diffusion KW - review KW - single-molecule KW - tirf AU - Jaiswal, Jyoti AU - Simon, Sanford PY - 2007/02// UR - http://dx.doi.org/10.1038/nchembio855 ER -