Current-day employment of the micro-bore open-tubular capillary column in the gas chromatography field
The present contribution is focused on the exploitation of the micro-bore (MB) open-tubular column (ID ≤ 0.18 mm), in current-day gas chromatography. The vast majority of GC methods involve the use of MB columns, from a variety of one-dimensional techniques (conventional and high speed), to different forms of heart-cutting and comprehensive multidimensional methodologies. Various aspects related to the use of MB open-tubular capillaries will be described and critically discussed, along with a series of pertinent applications. A series of works from the past have also been cited, essentially because many approaches today-applied, derive from the ideas of the past. Obviously, the present contribution does not review the entire history of the micro-bore capillary (more than one book would be necessary); rather, it intends to portray the great contribution that such analytical tools provide in enhancing two fundamental GC features, namely separation power and speed. âº An overview of the use of the open-tubular micro-bore column in one-dimensional GC applications. âº An overview of the use of the open-tubular micro-bore column in multidimensional GC-based methods. âº Requirements, advantages, and disadvantages related to the use of the open-tubular micro-bore column in the GC field.