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TrAC Trends in Analytical Chemistry, Vol. 46 (May 2013), pp. 189-197, doi:10.1016/j.trac.2013.02.003 Key: citeulike:12153875
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We outline the experiences and the challenges of optimizing two-dimensional gas chromatography coupled with time-of-flight mass spectrometry (GCxGC-TOF-MS) in conjunction with the H4IIE-luc bio-assay for analyzing polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in the South African context. Investigating such alternative analytical methods can assist countries with developing economies to meet their obligations under the Stockholm Convention. ⺠Developing countries need cost-effective methods to analyze organic pollutants. ⺠A combination of bio- and instrumental analysis can be used to obtain relevant ecotoxicological data. ⺠Care must be taken in implementation to focus on extraction and clean-up procedures.
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