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Mass Spectrometry Strategies in Metabolomics

by: Zhentian Lei, David V. Huhman, Lloyd W. Sumner
Journal of Biological Chemistry, Vol. 286, No. 29. (22 July 2011), pp. 25435-25442, doi:10.1074/jbc.r111.238691  Key: citeulike:9396416

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Abstract

MS has evolved as a critical component in metabolomics, which seeks to answer biological questions through large-scale qualitative and quantitative analyses of the metabolome. MS-based metabolomics techniques offer an excellent combination of sensitivity and selectivity, and they have become an indispensable platform in biology and metabolomics. In this minireview, various MS technologies used in metabolomics are briefly discussed, and future needs are suggested.


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