PKB/AKT: functional insights from genetic models. Export

@article{citeulike:2626948, abstract = {Since its discovery 10 years ago, the potential functions of protein kinase B (PKB)/AKT have been catalogued with increasing efficiency. The physiological relevance of some of the proposed mechanisms by which PKB/AKT mediates many of its effects has been questioned, and recent work using new reagents and approaches has revealed some cracks in our understanding of this important molecule, and also hinted that these effects may involve other players.}, address = {Ontario Cancer Institute, 610 University Avenue, Toronto, Ontario, Canada M5G 2M9.}, author = {Scheid, M. P. and Woodgett, J. R.}, citeulike-article-id = {2626948}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/35096067}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/11584303}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=11584303}, doi = {10.1038/35096067}, issn = {1471-0072}, journal = {Nature reviews. Molecular cell biology}, keywords = {akt, mapk}, month = {October}, number = {10}, pages = {760--768}, posted-at = {2008-04-03 18:14:33}, priority = {2}, title = {PKB/AKT: functional insights from genetic models.}, url = {http://dx.doi.org/10.1038/35096067}, volume = {2}, year = {2001} }

TY - JOUR ID - citeulike:2626948 L3 - citeulike-article-id:2626948 N2 - Since its discovery 10 years ago, the potential functions of protein kinase B (PKB)/AKT have been catalogued with increasing efficiency. The physiological relevance of some of the proposed mechanisms by which PKB/AKT mediates many of its effects has been questioned, and recent work using new reagents and approaches has revealed some cracks in our understanding of this important molecule, and also hinted that these effects may involve other players. IS - 10 JF - Nature reviews. Molecular cell biology SN - 1471-0072 AD - Ontario Cancer Institute, 610 University Avenue, Toronto, Ontario, Canada M5G 2M9. EP - 768 TI - PKB/AKT: functional insights from genetic models. VL - 2 SP - 760 KW - akt KW - mapk AU - Scheid, MP AU - Woodgett, JR PY - 2001/10// UR - http://dx.doi.org/10.1038/35096067 ER -