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Estudio histopatológico de la presencia de bacterias tipo Helicobacter pylori en especímenes quirúrgicos con colecistitis crónica

by: Gabriel Arismendi-Morillo, Verónica Cardozo-Ramones, Gustavo Torres-Nava, Zoila Romero-Amaro
Gastroenterología y Hepatología, Vol. 34, No. 7. (August 2011), pp. 449-453, doi:10.1016/j.gastrohep.2011.05.003  Key: citeulike:11335497

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Abstract

Recientemente se ha encontrado que especies de Helicobacter tienen alguna relación con ciertas enfermedades del árbol biliar; sin embargo, esto aún no está clara su vinculación y requiere mayores estudios. El propósito de este estudio fue determinar la presencia de bacterias tipo Helicobacter pylori (H. pylori) en pacientes con diagnóstico de colecistitis crónica, mediante el estudio histopatológico de los especímenes quirúrgicos de vesícula biliar. Se estudiaron anatomopatológicamente las piezas quirúrgicas de vesícula biliar de pacientes con diagnóstico de colecistitis crónica. Se establecieron las características macroscópicas de los especímenes. Los cortes histopatológicos se tiñeron con hematoxilina-eosina y con Giemsa. De los 68 pacientes a los que se practicó colecistectomía, 56 (81%) correspondieron a mujeres, y 12 (19%) hombres. La edad promedio fue 39,56 + 11,94 años. La presencia de bacterias tipo H. pylori fue de 6%. Los resultados de este estudio no permiten establecer que la presencia de las bacterias tipo H. pylori constituyan un factor importante en la etiología y/o patogenia de colecistitis crónica. En los pacientes con colecistitis crónica que reciben colecistectomía que se estudiaron en el presente trabajo, la etiología de la enfermedad crónica pudiese vincularse de manera más evidente con la presencia de formaciones calculosas. Helicobacter species have recently been found to be associated with some diseases of the biliary tree but this relationship remains unclear and further studies are required. The aim of this study was to determine the presence of H. pylori-type bacteria in patients with a diagnosis of chronic cholecystitis through histopathological study of surgical gallbladder specimens. Surgical gallbladder specimens from patients with a diagnosis of chronic cholecystitis were examined histopathologically. The macroscopic characteristics of the specimens were identified. Histopathological slices were stained with hematoxylin-eosin and Giemsa. Of the 68 patients who underwent cholecystectomy, 56 (81%) were women and 12 (19%) were men. The mean age was 39.56 + 11.94 years. H. pylori-type bacteria were found in 6%. The results of this study do not allow us to conclude that the presence of H. pylori-type bacteria is a major factor in the etiology and/or pathogenesis of chronic cholecystitis. In patients with chronic cholecystitis undergoing cholecystectomy included in the present study, the etiology of the disease may be more closely linked with the presence of gallstones.


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