Malaria and macrophage function in Africans: a possible link with autoimmune disease? Export

@article{citeulike:3347762, abstract = {Systemic lupus erythematosus and sarcoidosis, both diseases in which immune responses are aberrant, are not found in Africans in West Africa, but their prevalence in people of West African descent in the USA and UK is higher than that for white people. It is argued here that malaria both prevents these diseases in West Africa by its effects on macrophage function, and has also selected for a predisposition to them.}, address = {Department of Biology, Imperial College of Science, Technology and Medicine, London, UK. g.butcher@ic.ac.uk}, author = {Butcher, G. A.}, citeulike-article-id = {3347762}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/8869923}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=8869923}, issn = {0306-9877}, journal = {Medical hypotheses}, keywords = {malaria, sle, tnf}, month = {August}, number = {2}, pages = {97--100}, posted-at = {2008-09-28 21:24:39}, priority = {2}, title = {Malaria and macrophage function in Africans: a possible link with autoimmune disease?}, url = {http://view.ncbi.nlm.nih.gov/pubmed/8869923}, volume = {47}, year = {1996} }

TY - JOUR ID - citeulike:3347762 L3 - citeulike-article-id:3347762 N2 - Systemic lupus erythematosus and sarcoidosis, both diseases in which immune responses are aberrant, are not found in Africans in West Africa, but their prevalence in people of West African descent in the USA and UK is higher than that for white people. It is argued here that malaria both prevents these diseases in West Africa by its effects on macrophage function, and has also selected for a predisposition to them. IS - 2 JF - Medical hypotheses SN - 0306-9877 AD - Department of Biology, Imperial College of Science, Technology and Medicine, London, UK. g.butcher@ic.ac.uk EP - 100 TI - Malaria and macrophage function in Africans: a possible link with autoimmune disease? VL - 47 SP - 97 KW - malaria KW - sle KW - tnf AU - Butcher, GA PY - 1996/08// UR - http://view.ncbi.nlm.nih.gov/pubmed/8869923 ER -