Toll-like receptors in systemic lupus erythematosus prospects for therapeutic intervention. Export

@article{citeulike:3349436, abstract = {Recent experimental and clinical studies have placed new emphasis on the role of the innate immune system in SLE. Nucleic acid-containing immune complexes activate the innate response by engaging specific Toll-like receptors (TLRs) and promote the generation of autoantibodies. Pharmacologic modulation of TLR-directed pathways may offer new therapeutic approaches for the treatment of SLE.}, address = {Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, United States.}, author = {Kim, Wan-Uk U. and Sreih, Antoine and Bucala, Richard}, citeulike-article-id = {3349436}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.autrev.2008.07.046}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18722558}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18722558}, day = {20}, doi = {10.1016/j.autrev.2008.07.046}, issn = {1568-9972}, journal = {Autoimmunity reviews}, keywords = {like, receptors, sle, toll}, month = {August}, posted-at = {2008-09-29 02:22:02}, priority = {2}, title = {Toll-like receptors in systemic lupus erythematosus prospects for therapeutic intervention.}, url = {http://dx.doi.org/10.1016/j.autrev.2008.07.046}, year = {2008} }

TY - JOUR ID - citeulike:3349436 L3 - citeulike-article-id:3349436 N2 - Recent experimental and clinical studies have placed new emphasis on the role of the innate immune system in SLE. Nucleic acid-containing immune complexes activate the innate response by engaging specific Toll-like receptors (TLRs) and promote the generation of autoantibodies. Pharmacologic modulation of TLR-directed pathways may offer new therapeutic approaches for the treatment of SLE. JF - Autoimmunity reviews SN - 1568-9972 AD - Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, United States. TI - Toll-like receptors in systemic lupus erythematosus prospects for therapeutic intervention. KW - like KW - receptors KW - sle KW - toll AU - Kim, Wan-Uk AU - Sreih, Antoine AU - Bucala, Richard PY - 2008/08/20/ UR - http://dx.doi.org/10.1016/j.autrev.2008.07.046 ER -