Daily rhythms in PER1 within and beyond the suprachiasmatic nucleus of female grass rats (Arvicanthis niloticus). Export

@article{citeulike:3171012, abstract = {Although circadian rhythms of males and females are different in a variety of ways in many species, their mechanisms have been primarily studied in males. Furthermore, rhythms are dramatically different in diurnal and nocturnal animals but have been studied predominantly in nocturnal ones. In the present study, we examined rhythms in one element of the circadian oscillator, the PER1 protein, in a variety of cell populations in brains of diurnal female grass rats. Every 4 h five adult female grass rats kept on a 12-h light/dark (LD) cycle were perfused and their brains were processed for immunohistochemical detection of PER1. Numbers of PER1-labeled cells were rhythmic not only within the suprachiasmatic nucleus (SCN), the locus of the primary circadian clock in mammals, but also in the peri-suprachiasmatic region, the oval nucleus of the bed nucleus of the stria terminalis, the central amygdala, and the nucleus accumbens. In addition, rhythms were detected within populations of neuroendocrine cells that contain tyrosine hydroxylase. The phase of the rhythm within the SCN was advanced compared with that seen previously in male grass rats. Rhythms beyond the SCN were varied and different from those seen in most nocturnal species, suggesting that signals originating in the SCN are modified by its direct and/or indirect targets in different ways in nocturnal and diurnal species.}, address = {Department of Psychology, Michigan State University, East Lansing, MI 48824, USA; Neuroscience Program, Michigan State University, East Lansing, MI 48824, USA.}, author = {Ramanathan, C and Nunez, A A A. and Smale, L}, citeulike-article-id = {3171012}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.neuroscience.2008.07.020}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18692118}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18692118}, day = {18}, doi = {10.1016/j.neuroscience.2008.07.020}, issn = {0306-4522}, journal = {Neuroscience}, keywords = {amygdala, arcivanthis, circadian, nacc, obnst, per1, periscn, scn, sexual\_dimorphism}, month = {July}, posted-at = {2008-08-29 03:59:59}, priority = {4}, title = {Daily rhythms in PER1 within and beyond the suprachiasmatic nucleus of female grass rats (Arvicanthis niloticus).}, url = {http://dx.doi.org/10.1016/j.neuroscience.2008.07.020}, year = {2008} }

TY - JOUR ID - citeulike:3171012 L3 - citeulike-article-id:3171012 N2 - Although circadian rhythms of males and females are different in a variety of ways in many species, their mechanisms have been primarily studied in males. Furthermore, rhythms are dramatically different in diurnal and nocturnal animals but have been studied predominantly in nocturnal ones. In the present study, we examined rhythms in one element of the circadian oscillator, the PER1 protein, in a variety of cell populations in brains of diurnal female grass rats. Every 4 h five adult female grass rats kept on a 12-h light/dark (LD) cycle were perfused and their brains were processed for immunohistochemical detection of PER1. Numbers of PER1-labeled cells were rhythmic not only within the suprachiasmatic nucleus (SCN), the locus of the primary circadian clock in mammals, but also in the peri-suprachiasmatic region, the oval nucleus of the bed nucleus of the stria terminalis, the central amygdala, and the nucleus accumbens. In addition, rhythms were detected within populations of neuroendocrine cells that contain tyrosine hydroxylase. The phase of the rhythm within the SCN was advanced compared with that seen previously in male grass rats. Rhythms beyond the SCN were varied and different from those seen in most nocturnal species, suggesting that signals originating in the SCN are modified by its direct and/or indirect targets in different ways in nocturnal and diurnal species. JF - Neuroscience SN - 0306-4522 AD - Department of Psychology, Michigan State University, East Lansing, MI 48824, USA; Neuroscience Program, Michigan State University, East Lansing, MI 48824, USA. TI - Daily rhythms in PER1 within and beyond the suprachiasmatic nucleus of female grass rats (Arvicanthis niloticus). KW - amygdala KW - arcivanthis KW - circadian KW - nacc KW - obnst KW - per1 KW - periscn KW - scn KW - sexual_dimorphism AU - Ramanathan, C AU - Nunez, A A AU - Smale, L PY - 2008/07/18/ UR - http://dx.doi.org/10.1016/j.neuroscience.2008.07.020 ER -