Genome assembly forensics: finding the elusive mis-assembly Export

@article{citeulike:2535664, abstract = {We present the first collection of tools aimed at automated genome assembly validation. This work formalizes several mechanisms for detecting mis-assemblies, and describes their implementation in our automated validation pipeline, called amosvalidate. We demonstrate the application of our pipeline in both bacterial and eukaryotic genome assemblies, and highlight several assembly errors in both draft and finished genomes. The software described is compatible with common assembly formats and is released, open-source, at http://amos.sourceforge.net.}, author = {Phillippy, Adam and Schatz, Michael and Pop, Mihai}, citeulike-article-id = {2535664}, citeulike-linkout-0 = {http://dx.doi.org/10.1186/gb-2008-9-3-r55}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18341692}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18341692}, day = {14}, doi = {10.1186/gb-2008-9-3-r55}, issn = {1465-6906}, journal = {Genome Biology}, keywords = {algorithms, assembly, genome}, month = {March}, number = {3}, pages = {R55+}, posted-at = {2008-04-18 13:19:09}, priority = {2}, title = {Genome assembly forensics: finding the elusive mis-assembly}, url = {http://dx.doi.org/10.1186/gb-2008-9-3-r55}, volume = {9}, year = {2008} }

TY - JOUR ID - citeulike:2535664 L3 - citeulike-article-id:2535664 N2 - We present the first collection of tools aimed at automated genome assembly validation. This work formalizes several mechanisms for detecting mis-assemblies, and describes their implementation in our automated validation pipeline, called amosvalidate. We demonstrate the application of our pipeline in both bacterial and eukaryotic genome assemblies, and highlight several assembly errors in both draft and finished genomes. The software described is compatible with common assembly formats and is released, open-source, at http://amos.sourceforge.net. IS - 3 JF - Genome Biology SN - 1465-6906 TI - Genome assembly forensics: finding the elusive mis-assembly VL - 9 SP - R55 KW - algorithms KW - assembly KW - genome AU - Phillippy, Adam AU - Schatz, Michael AU - Pop, Mihai PY - 2008/03/14/ UR - http://dx.doi.org/10.1186/gb-2008-9-3-r55 ER -