UniPROBE: an online database of protein binding microarray data on protein-DNA interactions. Export

@article{UniPROBE, abstract = {The UniPROBE (Universal PBM Resource for Oligonucleotide Binding Evaluation) database hosts data generated by universal protein binding microarray (PBM) technology on the in vitro DNA-binding specificities of proteins. This initial release of the UniPROBE database provides a centralized resource for accessing comprehensive PBM data on the preferences of proteins for all possible sequence variants ('words') of length k ('k-mers'), as well as position weight matrix (PWM) and graphical sequence logo representations of the k-mer data. In total, the database hosts DNA-binding data for over 175 nonredundant proteins from a diverse collection of organisms, including the prokaryote Vibrio harveyi, the eukaryotic malarial parasite Plasmodium falciparum, the parasitic Apicomplexan Cryptosporidium parvum, the yeast Saccharomyces cerevisiae, the worm Caenorhabditis elegans, mouse and human. Current web tools include a text-based search, a function for assessing motif similarity between user-entered data and database PWMs, and a function for locating putative binding sites along user-entered nucleotide sequences. The UniPROBE database is available at http://thebrain.bwh.harvard.edu/uniprobe/.}, author = {Newburger, Daniel E E. and Bulyk, Martha L L.}, citeulike-article-id = {3399487}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/nar/gkn660}, citeulike-linkout-1 = {http://nar.oxfordjournals.org/cgi/content/abstract/37/suppl_1/D77}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/18842628}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=18842628}, day = {8}, doi = {10.1093/nar/gkn660}, issn = {1362-4962}, journal = {Nucleic acids research}, keywords = {database, phys\_props, prot\_binding}, month = {October}, posted-at = {2009-01-21 10:32:42}, priority = {2}, title = {UniPROBE: an online database of protein binding microarray data on protein-DNA interactions.}, url = {http://dx.doi.org/10.1093/nar/gkn660}, year = {2008} }

TY - JOUR ID - UniPROBE L3 - citeulike-article-id:3399487 N2 - The UniPROBE (Universal PBM Resource for Oligonucleotide Binding Evaluation) database hosts data generated by universal protein binding microarray (PBM) technology on the in vitro DNA-binding specificities of proteins. This initial release of the UniPROBE database provides a centralized resource for accessing comprehensive PBM data on the preferences of proteins for all possible sequence variants ('words') of length k ('k-mers'), as well as position weight matrix (PWM) and graphical sequence logo representations of the k-mer data. In total, the database hosts DNA-binding data for over 175 nonredundant proteins from a diverse collection of organisms, including the prokaryote Vibrio harveyi, the eukaryotic malarial parasite Plasmodium falciparum, the parasitic Apicomplexan Cryptosporidium parvum, the yeast Saccharomyces cerevisiae, the worm Caenorhabditis elegans, mouse and human. Current web tools include a text-based search, a function for assessing motif similarity between user-entered data and database PWMs, and a function for locating putative binding sites along user-entered nucleotide sequences. The UniPROBE database is available at http://thebrain.bwh.harvard.edu/uniprobe/. JF - Nucleic acids research SN - 1362-4962 TI - UniPROBE: an online database of protein binding microarray data on protein-DNA interactions. KW - database KW - phys_props KW - prot_binding AU - Newburger, Daniel E AU - Bulyk, Martha L PY - 2008/10/08/ UR - http://dx.doi.org/10.1093/nar/gkn660 ER -