Rapid DNA loss as a counterbalance to genome expansion through retrotransposon proliferation in plants. Export

@article{citeulike:5915696, abstract = {Transposable elements, particularly LTR-retrotransposons, comprise the primary vehicle for genome size expansion in plants, while DNA removal through illegitimate recombination and intrastrand homologous recombination serve as the most important counteracting forces to plant genomic obesity. Despite extensive research, the relative impact of these opposing forces and hence the directionality of genome size change remains unknown. In Gossypium (cotton), the 3-fold genome size variation among diploids is due largely to copy number variation of the gypsy-like retrotransposon Gorge3. Here we combine comparative sequence analysis with a modeling approach to study the directionality of genome size change in Gossypium. We demonstrate that the rate of DNA removal in the smaller genomes is sufficient to reverse genome expansion through Gorge3 proliferation. These data indicate that rates of DNA loss can be highly variable even within a single plant genus, and that the known mechanisms of DNA loss can indeed reverse the march toward genomic obesity.}, author = {Hawkins, Jennifer S. and Proulx, Stephen R. and Rapp, Ryan A. and Wendel, Jonathan F.}, citeulike-article-id = {5915696}, citeulike-linkout-0 = {http://dx.doi.org/10.1073/pnas.0904339106}, citeulike-linkout-1 = {http://www.pnas.org/content/early/2009/10/06/0904339106.abstract}, citeulike-linkout-2 = {http://www.pnas.org/content/early/2009/10/06/0904339106.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/19815511}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=19815511}, day = {7}, doi = {10.1073/pnas.0904339106}, issn = {1091-6490}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, keywords = {deletion, plants}, month = {October}, posted-at = {2009-10-20 19:54:39}, priority = {2}, title = {Rapid DNA loss as a counterbalance to genome expansion through retrotransposon proliferation in plants.}, url = {http://dx.doi.org/10.1073/pnas.0904339106}, year = {2009} }

TY - JOUR ID - citeulike:5915696 L3 - citeulike-article-id:5915696 N2 - Transposable elements, particularly LTR-retrotransposons, comprise the primary vehicle for genome size expansion in plants, while DNA removal through illegitimate recombination and intrastrand homologous recombination serve as the most important counteracting forces to plant genomic obesity. Despite extensive research, the relative impact of these opposing forces and hence the directionality of genome size change remains unknown. In Gossypium (cotton), the 3-fold genome size variation among diploids is due largely to copy number variation of the gypsy-like retrotransposon Gorge3. Here we combine comparative sequence analysis with a modeling approach to study the directionality of genome size change in Gossypium. We demonstrate that the rate of DNA removal in the smaller genomes is sufficient to reverse genome expansion through Gorge3 proliferation. These data indicate that rates of DNA loss can be highly variable even within a single plant genus, and that the known mechanisms of DNA loss can indeed reverse the march toward genomic obesity. JF - Proceedings of the National Academy of Sciences of the United States of America SN - 1091-6490 TI - Rapid DNA loss as a counterbalance to genome expansion through retrotransposon proliferation in plants. KW - deletion KW - plants AU - Hawkins, Jennifer AU - Proulx, Stephen AU - Rapp, Ryan AU - Wendel, Jonathan PY - 2009/10/07/ UR - http://dx.doi.org/10.1073/pnas.0904339106 ER -