Pathophysiology of sperm motility. Export

@article{LuconiForti2006, abstract = {Mammalian spermatozoa acquire the ability to swim during their transit from the testis to the oviduct under the control of several external and intracellular factors. These factors play also a pivotal role in regulating acquisition of hyperactivated motility and during the process of chemotaxis. This review summarizes the involvement of such factors in acquisition and maintenance of sperm motility, hyperactivation and chemotaxis, focusing in particular on the molecular bases of asthenozoospermia, a pathology of seminal plasma characterized by reduced sperm motility, which is one of the main causes of male infertility. Current in vitro treatments of asthenozoospermia are shown, together with the most recent findings on pharmacological and physiological molecules capable of stimulating sperm motility. The structure, function and mechanism of sperm flagellum responsible for the development of active motility are also analyzed in details.}, author = {Luconi, M. and Forti, G. and Baldi, E.}, citeulike-article-id = {3859950}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/16368527}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=16368527}, issn = {1093-4715}, journal = {Frontiers in bioscience : a journal and virtual library}, keywords = {oviduct-comp-model}, pages = {1433--1447}, posted-at = {2009-01-08 12:35:17}, priority = {2}, title = {Pathophysiology of sperm motility.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/16368527}, volume = {11}, year = {2006} }

TY - JOUR ID - LuconiForti2006 L3 - citeulike-article-id:3859950 N2 - Mammalian spermatozoa acquire the ability to swim during their transit from the testis to the oviduct under the control of several external and intracellular factors. These factors play also a pivotal role in regulating acquisition of hyperactivated motility and during the process of chemotaxis. This review summarizes the involvement of such factors in acquisition and maintenance of sperm motility, hyperactivation and chemotaxis, focusing in particular on the molecular bases of asthenozoospermia, a pathology of seminal plasma characterized by reduced sperm motility, which is one of the main causes of male infertility. Current in vitro treatments of asthenozoospermia are shown, together with the most recent findings on pharmacological and physiological molecules capable of stimulating sperm motility. The structure, function and mechanism of sperm flagellum responsible for the development of active motility are also analyzed in details. JF - Frontiers in bioscience : a journal and virtual library SN - 1093-4715 EP - 1447 TI - Pathophysiology of sperm motility. VL - 11 SP - 1433 KW - oviduct-comp-model AU - Luconi, M AU - Forti, G AU - Baldi, E PY - 2006/// UR - http://view.ncbi.nlm.nih.gov/pubmed/16368527 ER -