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miR-1-2 Gets to the Heart of the Matter.

Cell, Vol. 129, No. 2. (20 April 2007), pp. 247-249.


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Although many microRNAs (miRNAs) and their targets have been identified, the importance of miRNAs in vivo is still unclear. In this issue, Zhao et al. (2007) generate mice deficient in a cardiac-specific miRNA, miR-1-2, and reveal that this microRNA plays a crucial role in heart development and physiology.


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