Complementary 'bottom-up' and 'top-down' approaches to basal ganglia function Export

@article{citeulike:4937509, abstract = {Recently, two quite different approaches exemplifying 'bottom-up' and 'top-down' philosophies have shed new light on basal ganglia function. In vitro work using organotypic co-cultures has implicated the subthalamic nucleus (STN) and the external segment of the globus pallidus (GP e ) as pacemakers for low-frequency bursting that is reminiscent of the activity produced in Parkinsonian tremor. A circuit essential for avian song learning has been identified as part of the basal ganglia with surprisingly well conserved cellular details; investigation of this system may help to address general issues of basal ganglia function.}, author = {Perkel, D.}, citeulike-article-id = {4937509}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/S0959-4388(00)00156-2}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0959-4388(00)00156-2}, day = {1}, doi = {10.1016/S0959-4388(00)00156-2}, issn = {09594388}, journal = {Current Opinion in Neurobiology}, keywords = {basalganglia, birdsong, brain}, month = {December}, number = {6}, pages = {725--731}, posted-at = {2009-06-23 22:44:43}, priority = {2}, title = {Complementary 'bottom-up' and 'top-down' approaches to basal ganglia function}, url = {http://dx.doi.org/10.1016/S0959-4388(00)00156-2}, volume = {10}, year = {2000} }

TY - JOUR ID - citeulike:4937509 L3 - citeulike-article-id:4937509 N2 - Recently, two quite different approaches exemplifying ‘bottom-up’ and ‘top-down’ philosophies have shed new light on basal ganglia function. In vitro work using organotypic co-cultures has implicated the subthalamic nucleus (STN) and the external segment of the globus pallidus (GP e ) as pacemakers for low-frequency bursting that is reminiscent of the activity produced in Parkinsonian tremor. A circuit essential for avian song learning has been identified as part of the basal ganglia with surprisingly well conserved cellular details; investigation of this system may help to address general issues of basal ganglia function. IS - 6 JF - Current Opinion in Neurobiology SN - 09594388 EP - 731 TI - Complementary 'bottom-up' and 'top-down' approaches to basal ganglia function VL - 10 SP - 725 KW - basalganglia KW - birdsong KW - brain AU - Perkel, D PY - 2000/12/01/ UR - http://dx.doi.org/10.1016/S0959-4388(00)00156-2 ER -