Predicting protein function from sequence and structure. Export

@article{citeulike:1986332, abstract = {While the number of sequenced genomes continues to grow, experimentally verified functional annotation of whole genomes remains patchy. Structural genomics projects are yielding many protein structures that have unknown function. Nevertheless, subsequent experimental investigation is costly and time-consuming, which makes computational methods for predicting protein function very attractive. There is an increasing number of noteworthy methods for predicting protein function from sequence and structural data alone, many of which are readily available to cell biologists who are aware of the strengths and pitfalls of each available technique.}, author = {Lee, D. and Redfern, O. and Orengo, C.}, citeulike-article-id = {1986332}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nrm2281}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nrm2281}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/18037900}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=18037900}, doi = {10.1038/nrm2281}, issn = {1471-0080}, journal = {Nature reviews. Molecular cell biology}, keywords = {genome-annotation}, month = {December}, number = {12}, pages = {995--1005}, posted-at = {2009-07-02 16:24:28}, priority = {4}, publisher = {Nature Publishing Group}, title = {Predicting protein function from sequence and structure.}, url = {http://dx.doi.org/10.1038/nrm2281}, volume = {8}, year = {2007} }

TY - JOUR ID - citeulike:1986332 L3 - citeulike-article-id:1986332 N2 - While the number of sequenced genomes continues to grow, experimentally verified functional annotation of whole genomes remains patchy. Structural genomics projects are yielding many protein structures that have unknown function. Nevertheless, subsequent experimental investigation is costly and time-consuming, which makes computational methods for predicting protein function very attractive. There is an increasing number of noteworthy methods for predicting protein function from sequence and structural data alone, many of which are readily available to cell biologists who are aware of the strengths and pitfalls of each available technique. IS - 12 JF - Nature reviews. Molecular cell biology SN - 1471-0080 EP - 1005 TI - Predicting protein function from sequence and structure. PB - Nature Publishing Group VL - 8 SP - 995 KW - genome-annotation AU - Lee, D AU - Redfern, O AU - Orengo, C PY - 2007/12// UR - http://dx.doi.org/10.1038/nrm2281 ER -