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An Introduction to the Informatics of “Next-Generation” Sequencing

by: Lincoln D. Stein
Current protocols in bioinformatics / editoral board, Andreas D. Baxevanis ... [et al.] In Current Protocols in Bioinformatics, Vol. Chapter 11 (December 2002), doi:10.1002/0471250953.bi1101s36  Key: citeulike:10163412

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Abstract

Next-generation sequencing (NGS) packs the sequencing throughput of a 2000's-era genome center into a single affordable machine. However, software developed for conventional sequencing technologies is often inadequate to deal with the nature of NGS technologies, which produce short, massively parallel reads. This unit surveys the software packages that are available for managing and analyzing NGS data. Curr. Protoc. Bioinform. 36:11.1.1-11.1.9. © 2011 by John Wiley & Sons, Inc.


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