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Use of classification trees for association studies. Export

Genetic epidemiology, Vol. 19, No. 4. (December 2000), pp. 323-332.

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association classification epistasis statistics

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We propose the use of classification trees for association studies. This approach is applied to a data set from Genetic Analysis Workshop 9 (GAW9), and our analysis precisely identified two disease alleles. Our purpose is to demonstrate the great potential of tree-based analyses for genetic studies, and discuss some issues that warrant further investigation.


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