From in vivo to in silico biology and back Export

@article{citeulike:884973, abstract = {The massive acquisition of data in molecular and cellular biology has led to the renaissance of an old topic: simulations of biological systems. Simulations, increasingly paired with experiments, are being successfully and routinely used by computational biologists to understand and predict the quantitative behaviour of complex systems, and to drive new experiments. Nevertheless, many experimentalists still consider simulations an esoteric discipline only for initiates. Suspicion towards simulations should dissipate as the limitations and advantages of their application are better appreciated, opening the door to their permanent adoption in everyday research.}, author = {Di Ventura, Barbara and Lemerle, Caroline and Michalodimitrakis, Konstantinos and Serrano, Luis}, citeulike-article-id = {884973}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nature05127}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nature05127}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/17024084}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=17024084}, day = {05}, doi = {10.1038/nature05127}, issn = {0028-0836}, journal = {Nature}, keywords = {modelling, synthetic\_biology, systems\_biology}, month = {October}, number = {7111}, pages = {527--533}, posted-at = {2006-10-17 17:29:36}, priority = {2}, publisher = {Nature Publishing Group}, title = {From in vivo to in silico biology and back}, url = {http://dx.doi.org/10.1038/nature05127}, volume = {443}, year = {2006} }

TY - JOUR ID - citeulike:884973 L3 - citeulike-article-id:884973 N2 - The massive acquisition of data in molecular and cellular biology has led to the renaissance of an old topic: simulations of biological systems. Simulations, increasingly paired with experiments, are being successfully and routinely used by computational biologists to understand and predict the quantitative behaviour of complex systems, and to drive new experiments. Nevertheless, many experimentalists still consider simulations an esoteric discipline only for initiates. Suspicion towards simulations should dissipate as the limitations and advantages of their application are better appreciated, opening the door to their permanent adoption in everyday research. IS - 7111 JF - Nature SN - 0028-0836 EP - 533 TI - From in vivo to in silico biology and back PB - Nature Publishing Group VL - 443 SP - 527 KW - modelling KW - synthetic_biology KW - systems_biology AU - Di Ventura, Barbara AU - Lemerle, Caroline AU - Michalodimitrakis, Konstantinos AU - Serrano, Luis PY - 2006/10/05/ UR - http://dx.doi.org/10.1038/nature05127 ER -