Physical activity and clustered cardiovascular risk in children: a cross-sectional study (The European Youth Heart Study) Export

@article{citeulike:1281233, abstract = {SummaryBackground Atherosclerosis develops from early childhood; physical activity could positively affect this process. This study's aim was to assess the associations of objectively measured physical activity with clustering of cardiovascular disease risk factors in children and derive guidelines on the basis of this analysis.Methods We did a cross-sectional study of 1732 randomly selected 9-year-old and 15-year-old school children from Denmark, Estonia, and Portugal. Risk factors included in the composite risk factor score (mean of Z scores) were systolic blood pressure, triglyceride, total cholesterol/HDL ratio, insulin resistance, sum of four skinfolds, and aerobic fitness. Individuals with a risk score above 1 SD of the composite variable were defined as being at risk. Physical activity was assessed by accelerometry.Findings Odds ratios for having clustered risk for ascending quintiles of physical activity (counts per min; cpm) were 3[middle dot]29 (95\% CI 1[middle dot]96-5[middle dot]52), 3[middle dot]13 (1[middle dot]87-5[middle dot]25), 2[middle dot]51 (1[middle dot]47-4[middle dot]26), and 2[middle dot]03 (1[middle dot]18-3[middle dot]50), respectively, compared with the most active quintile. The first to the third quintile of physical activity had a raised risk in all analyses. The mean time spent above 2000 cpm in the fourth quintile was 116 min per day in 9-year-old and 88 min per day in 15-year-old children.Interpretation Physical activity levels should be higher than the current international guidelines of at least 1 h per day of physical activity of at least moderate intensity to prevent clustering of cardiovascular disease risk factors.}, author = {Andersen, Lars B. and Harro, Maarike and Sardinha, Luis B. and Froberg, Karsten and Ekelund, Ulf and Brage, Soren and Anderssen, Sigmund A.}, citeulike-article-id = {1281233}, citeulike-linkout-0 = {http://www.sciencedirect.com/science/article/B6T1B-4KFNKH6-10/2/a121e3f8fb949bb8e2e38b9bf209dd6b}, citeulike-linkout-1 = {http://dx.doi.org/doi:10.1016/S0140-6736(06)69075-2}, doi = {doi:10.1016/S0140-6736(06)69075-2}, journal = {The Lancet}, keywords = {bicycle, cardiovascular\_risk, children, health, medicine, obesity}, number = {9532}, pages = {299--304}, posted-at = {2007-05-07 00:55:29}, priority = {5}, title = {Physical activity and clustered cardiovascular risk in children: a cross-sectional study (The European Youth Heart Study)}, url = {http://dx.doi.org/doi:10.1016/S0140-6736(06)69075-2}, volume = {368} }

TY - JOUR ID - citeulike:1281233 L3 - citeulike-article-id:1281233 N2 - SummaryBackground Atherosclerosis develops from early childhood; physical activity could positively affect this process. This study's aim was to assess the associations of objectively measured physical activity with clustering of cardiovascular disease risk factors in children and derive guidelines on the basis of this analysis.Methods We did a cross-sectional study of 1732 randomly selected 9-year-old and 15-year-old school children from Denmark, Estonia, and Portugal. Risk factors included in the composite risk factor score (mean of Z scores) were systolic blood pressure, triglyceride, total cholesterol/HDL ratio, insulin resistance, sum of four skinfolds, and aerobic fitness. Individuals with a risk score above 1 SD of the composite variable were defined as being at risk. Physical activity was assessed by accelerometry.Findings Odds ratios for having clustered risk for ascending quintiles of physical activity (counts per min; cpm) were 3[middle dot]29 (95% CI 1[middle dot]96-5[middle dot]52), 3[middle dot]13 (1[middle dot]87-5[middle dot]25), 2[middle dot]51 (1[middle dot]47-4[middle dot]26), and 2[middle dot]03 (1[middle dot]18-3[middle dot]50), respectively, compared with the most active quintile. The first to the third quintile of physical activity had a raised risk in all analyses. The mean time spent above 2000 cpm in the fourth quintile was 116 min per day in 9-year-old and 88 min per day in 15-year-old children.Interpretation Physical activity levels should be higher than the current international guidelines of at least 1 h per day of physical activity of at least moderate intensity to prevent clustering of cardiovascular disease risk factors. IS - 9532 JF - The Lancet EP - 304 TI - Physical activity and clustered cardiovascular risk in children: a cross-sectional study (The European Youth Heart Study) VL - 368 SP - 299 KW - bicycle KW - cardiovascular_risk KW - children KW - health KW - medicine KW - obesity AU - Andersen, Lars AU - Harro, Maarike AU - Sardinha, Luis AU - Froberg, Karsten AU - Ekelund, Ulf AU - Brage, Soren AU - Anderssen, Sigmund UR - http://dx.doi.org/doi:10.1016/S0140-6736(06)69075-2 ER -