Rapid and slow changes in the human cone electroretinogram during light and dark adaptation. Export

@article{citeulike:771661, abstract = {Changes in the response characteristics of the human cone electroretinogram (ERG) during light and dark adaptation were studied in two visually normal subjects. Cone ERG responses were isolated under all adaptation conditions through the use of 31 Hz flicker. To determine the time-course of changes in the cone ERG during adaptation, responses to stimuli of constant luminance were measured repeatedly during 15 min of exposure to an adapting field of 2.0 log cd/m2 and during 30 min of dark adaptation following adapting field termination. In addition, luminance-response functions were obtained before and immediately after adapting field onset, as well as before and immediately after adapting field termination. The results indicate that the human cone ERG is influenced by two major processes. One process has a relatively rapid time-course and serves to reposition the luminance-response function along the luminance axis following changes in ambient light levels. The second process, which has a slow time-course, scales response amplitudes during light and dark adaptation by the same proportion at all stimulus luminances. The results provide a framework for predicting the manner in which the cone ERG will change with alterations in the state of retinal adaptation.}, address = {Hines VA Hospital, IL 60141.}, author = {Peachey, N. S. and Arakawa, K. and Alexander, K. R. and Marchese, A. L.}, citeulike-article-id = {771661}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/1304082}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=1304082}, issn = {0042-6989}, journal = {Vision Res}, keywords = {cones, dark\_adaptation}, month = {November}, number = {11}, pages = {2049--2053}, posted-at = {2006-07-24 18:22:50}, priority = {2}, title = {Rapid and slow changes in the human cone electroretinogram during light and dark adaptation.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/1304082}, volume = {32}, year = {1992} }

TY - JOUR ID - citeulike:771661 L3 - citeulike-article-id:771661 N2 - Changes in the response characteristics of the human cone electroretinogram (ERG) during light and dark adaptation were studied in two visually normal subjects. Cone ERG responses were isolated under all adaptation conditions through the use of 31 Hz flicker. To determine the time-course of changes in the cone ERG during adaptation, responses to stimuli of constant luminance were measured repeatedly during 15 min of exposure to an adapting field of 2.0 log cd/m2 and during 30 min of dark adaptation following adapting field termination. In addition, luminance-response functions were obtained before and immediately after adapting field onset, as well as before and immediately after adapting field termination. The results indicate that the human cone ERG is influenced by two major processes. One process has a relatively rapid time-course and serves to reposition the luminance-response function along the luminance axis following changes in ambient light levels. The second process, which has a slow time-course, scales response amplitudes during light and dark adaptation by the same proportion at all stimulus luminances. The results provide a framework for predicting the manner in which the cone ERG will change with alterations in the state of retinal adaptation. IS - 11 JF - Vision Res SN - 0042-6989 AD - Hines VA Hospital, IL 60141. EP - 2053 TI - Rapid and slow changes in the human cone electroretinogram during light and dark adaptation. VL - 32 SP - 2049 KW - cones KW - dark_adaptation AU - Peachey, NS AU - Arakawa, K AU - Alexander, KR AU - Marchese, AL PY - 1992/11// UR - http://view.ncbi.nlm.nih.gov/pubmed/1304082 ER -