Sponge Paleogenomics Reveals an Ancient Role for Carbonic Anhydrase in Skeletogenesis. Export

@article{citeulike:1373122, abstract = {Sponges (Porifera) were prolific reef-building organisms during the Paleozoic and Mesozoic. These ancient animals inherited components of the first multicellular skeletogenic toolkit from the last common ancestor of the Metazoa (LCAM). Using a paleogenomics approach, including gene and protein expression techniques and phylogenetic reconstruction, we show that a molecular component of this toolkit was the precursor to the alpha-carbonic anhydrases, a gene family used by extant animals in a variety of fundamental physiological processes. We used the coralline demosponge Astrosclera willeyana, a 'living fossil' that has survived from the Mesozoic, to provide insight into the evolution of the ability to biocalcify, and show that the alpha-CA family expanded from a single ancestral gene through several independent gene duplication events in sponges and eumetazoans.}, address = {Geoscience Centre G\"{o}ttingen, Department of Geobiology, Goldschmidtstr. 3, D-37077 G\"{o}ttingen, Germany; School of Integrative Biology, University of Queensland, Brisbane 4072, Australia.}, author = {Jackson, Daniel J J. and Macis, Luciana and Reitner, Joachim and Degnan, Bernard M M. and W\"{o}rheide, Gert}, citeulike-article-id = {1373122}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.1141560}, citeulike-linkout-1 = {http://www.sciencemag.org/cgi/content/abstract/316/5833/1893}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/17540861}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=17540861}, day = {31}, doi = {10.1126/science.1141560}, issn = {1095-9203}, journal = {Science}, keywords = {early-animals, evolution, sponges}, month = {May}, posted-at = {2007-06-29 20:50:42}, priority = {2}, title = {Sponge Paleogenomics Reveals an Ancient Role for Carbonic Anhydrase in Skeletogenesis.}, url = {http://dx.doi.org/10.1126/science.1141560}, year = {2007} }

TY - JOUR ID - citeulike:1373122 L3 - citeulike-article-id:1373122 N2 - Sponges (Porifera) were prolific reef-building organisms during the Paleozoic and Mesozoic. These ancient animals inherited components of the first multicellular skeletogenic toolkit from the last common ancestor of the Metazoa (LCAM). Using a paleogenomics approach, including gene and protein expression techniques and phylogenetic reconstruction, we show that a molecular component of this toolkit was the precursor to the alpha-carbonic anhydrases, a gene family used by extant animals in a variety of fundamental physiological processes. We used the coralline demosponge Astrosclera willeyana, a 'living fossil' that has survived from the Mesozoic, to provide insight into the evolution of the ability to biocalcify, and show that the alpha-CA family expanded from a single ancestral gene through several independent gene duplication events in sponges and eumetazoans. JF - Science SN - 1095-9203 AD - Geoscience Centre Göttingen, Department of Geobiology, Goldschmidtstr. 3, D-37077 Göttingen, Germany; School of Integrative Biology, University of Queensland, Brisbane 4072, Australia. TI - Sponge Paleogenomics Reveals an Ancient Role for Carbonic Anhydrase in Skeletogenesis. KW - early-animals KW - evolution KW - sponges AU - Jackson, Daniel J AU - Macis, Luciana AU - Reitner, Joachim AU - Degnan, Bernard M AU - Wörheide, Gert PY - 2007/05/31/ UR - http://dx.doi.org/10.1126/science.1141560 ER -