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Tools for mapping high-throughput sequencing data

by: Nuno A. Fonseca, Johan Rung, Alvis Brazma, John C. Marioni
Bioinformatics, Vol. 28, No. 24. (11 October 2012), pp. 3169-3177, doi:10.1093/bioinformatics/bts605  Key: citeulike:11446264

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Abstract

Motivation: A ubiquitous and fundamental step in high-throughput sequencing analysis is the alignment (mapping) of the generated reads to a reference sequence. To accomplish this task numerous software tools have been proposed. Determining the mappers that are most suitable for a specific application is not trivial.


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