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Multiple neural spike train data analysis: state-of-the-art and future challenges. Export

Nat Neurosci, Vol. 7, No. 5. (May 2004), pp. 456-461.

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15114358 action algorithms animals art bibtex-import biological brain cerebral cognition computer conduction cortex cortical deep dendrites design disorders dynamics electric electrophysiology factors gravitation hippocampus humans mapping models nerve net networks neural neurological neurons nonlinear of pathways potentials prosthesis reproducibility results simulation statistics stimulation synaptic synchronization time transmission

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Multiple electrodes are now a standard tool in neuroscience research that make it possible to study the simultaneous activity of several neurons in a given brain region or across different regions. The data from multi-electrode studies present important analysis challenges that must be resolved for optimal use of these neurophysiological measurements to answer questions about how the brain works. Here we review statistical methods for the analysis of multiple neural spike-train data and discuss future challenges for methodology research.


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