Cortical ensemble activity increasingly predicts behaviour outcomes during learning of a motor task. Export

@article{Laubach2000, abstract = {When an animal learns to make movements in response to different stimuli, changes in activity in the motor cortex seem to accompany and underlie this learning. The precise nature of modifications in cortical motor areas during the initial stages of motor learning, however, is largely unknown. Here we address this issue by chronically recording from neuronal ensembles located in the rat motor cortex, throughout the period required for rats to learn a reaction-time task. Motor learning was demonstrated by a decrease in the variance of the rats' reaction times and an increase in the time the animals were able to wait for a trigger stimulus. These behavioural changes were correlated with a significant increase in our ability to predict the correct or incorrect outcome of single trials based on three measures of neuronal ensemble activity: average firing rate, temporal patterns of firing, and correlated firing. This increase in prediction indicates that an association between sensory cues and movement emerged in the motor cortex as the task was learned. Such modifications in cortical ensemble activity may be critical for the initial learning of motor tasks.}, author = {Laubach, M. and Wessberg, J. and Nicolelis, M. A.}, citeulike-article-id = {1851085}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/35014604}, doi = {10.1038/35014604}, journal = {Nature}, keywords = {10850698, action, activity, algorithms, analysis, animals, aotidae, aotus, arm, artificial, automated, bibtex-import, biomechanics, brain, cerebral, computer, computer-assisted, conduction, cortex, diagnosis, dynamics, electroencephalography, electromyography, electrophysiology, evoked, factors, feedback, frontal, functional, hand, intelligence, interface, laterality, learning, limbs, linear, lobe, male, mapping, models, motor, movement, networks, neural, neurological, neurons, nonlinear, of, parietal, pattern, perception, performance, potentials, psychomotor, rats, reaction, recognition, robotics, signal, skills, space, time, transduction, trivirgatus, user-computer, variance}, month = {Jun}, number = {6786}, pages = {567--571}, posted-at = {2007-11-01 13:26:49}, priority = {2}, title = {{C}ortical ensemble activity increasingly predicts behaviour outcomes during learning of a motor task.}, url = {10.1038/35014604}, volume = {405}, year = {2000} }

TY - JOUR ID - Laubach2000 L3 - citeulike-article-id:1851085 N2 - When an animal learns to make movements in response to different stimuli, changes in activity in the motor cortex seem to accompany and underlie this learning. The precise nature of modifications in cortical motor areas during the initial stages of motor learning, however, is largely unknown. Here we address this issue by chronically recording from neuronal ensembles located in the rat motor cortex, throughout the period required for rats to learn a reaction-time task. Motor learning was demonstrated by a decrease in the variance of the rats' reaction times and an increase in the time the animals were able to wait for a trigger stimulus. These behavioural changes were correlated with a significant increase in our ability to predict the correct or incorrect outcome of single trials based on three measures of neuronal ensemble activity: average firing rate, temporal patterns of firing, and correlated firing. This increase in prediction indicates that an association between sensory cues and movement emerged in the motor cortex as the task was learned. Such modifications in cortical ensemble activity may be critical for the initial learning of motor tasks. IS - 6786 JF - Nature EP - 571 TI - {C}ortical ensemble activity increasingly predicts behaviour outcomes during learning of a motor task. VL - 405 SP - 567 KW - 10850698 KW - action KW - activity KW - algorithms KW - analysis KW - animals KW - aotidae KW - aotus KW - arm KW - artificial KW - automated KW - bibtex-import KW - biomechanics KW - brain KW - cerebral KW - computer KW - computer-assisted KW - conduction KW - cortex KW - diagnosis KW - dynamics KW - electroencephalography KW - electromyography KW - electrophysiology KW - evoked KW - factors KW - feedback KW - frontal KW - functional KW - hand KW - intelligence KW - interface KW - laterality KW - learning KW - limbs KW - linear KW - lobe KW - male KW - mapping KW - models KW - motor KW - movement KW - networks KW - neural KW - neurological KW - neurons KW - nonlinear KW - of KW - parietal KW - pattern KW - perception KW - performance KW - potentials KW - psychomotor KW - rats KW - reaction KW - recognition KW - robotics KW - signal KW - skills KW - space KW - time KW - transduction KW - trivirgatus KW - user-computer KW - variance AU - Laubach, M AU - Wessberg, J AU - Nicolelis, MA PY - 2000/Jun// UR - http://dx.doi.org/10.1038/35014604 ER -