Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases. Export

@article{citeulike:3884172, abstract = {We define phosphovariants as genetic variations that change phosphorylation sites or their interacting kinases. Considering the essential role of phosphorylation in protein functions, it is highly likely that phosphovariants change protein functions. Therefore, a comparison of phosphovariants between individuals or between species can give clues about phenotypic differences. We categorized phosphovariants into three subtypes and developed a system that predicts them. Our method can be used to screen important polymorphisms and help to identify the mechanisms of genetic diseases.}, author = {Ryu, Gil-Mi M. and Song, Pamela and Kim, Kyu-Won W. and Oh, Kyung-Soo S. and Park, Keun-Joon J. and Kim, Jong Hun H.}, citeulike-article-id = {3884172}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/nar/gkn1008}, citeulike-linkout-1 = {http://nar.oxfordjournals.org/cgi/content/abstract/37/4/1297}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/19139070}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=19139070}, day = {12}, doi = {10.1093/nar/gkn1008}, issn = {1362-4962}, journal = {Nucleic acids research}, keywords = {analysis, genomics, kinase, phosphorylation, protein, sequence, variation}, month = {March}, number = {4}, pages = {1297--1307}, posted-at = {2009-01-14 02:00:37}, priority = {2}, title = {Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.}, url = {http://dx.doi.org/10.1093/nar/gkn1008}, volume = {37}, year = {2009} }

TY - JOUR ID - citeulike:3884172 L3 - citeulike-article-id:3884172 N2 - We define phosphovariants as genetic variations that change phosphorylation sites or their interacting kinases. Considering the essential role of phosphorylation in protein functions, it is highly likely that phosphovariants change protein functions. Therefore, a comparison of phosphovariants between individuals or between species can give clues about phenotypic differences. We categorized phosphovariants into three subtypes and developed a system that predicts them. Our method can be used to screen important polymorphisms and help to identify the mechanisms of genetic diseases. IS - 4 JF - Nucleic acids research SN - 1362-4962 EP - 1307 TI - Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases. VL - 37 SP - 1297 KW - analysis KW - genomics KW - kinase KW - phosphorylation KW - protein KW - sequence KW - variation AU - Ryu, Gil-Mi AU - Song, Pamela AU - Kim, Kyu-Won AU - Oh, Kyung-Soo AU - Park, Keun-Joon AU - Kim, Jong Hun PY - 2009/03/12/ UR - http://dx.doi.org/10.1093/nar/gkn1008 ER -