The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution Export

@article{citeulike:4388822, abstract = {To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a core set of 14,345 orthologs shared among seven mammalian species of which 1217 are absent or undetected in noneutherian (marsupial or monotreme) genomes. Cattle-specific evolutionary breakpoint regions in chromosomes have a higher density of segmental duplications, enrichment of repetitive elements, and species-specific variations in genes associated with lactation and immune responsiveness. Genes involved in metabolism are generally highly conserved, although five metabolic genes are deleted or extensively diverged from their human orthologs. The cattle genome sequence thus provides a resource for understanding mammalian evolution and accelerating livestock genetic improvement for milk and meat production. 10.1126/science.1169588}, author = {The Bovine Genome Sequencing and Analysis Consortium and Elsik, Christine G. and Tellam, Ross L. and Worley, Kim C. and Gibbs, Richard A. and Muzny, Donna M. and Weinstock, George M. and Adelson, David L. and Eichler, Evan E. and Elnitski, Laura and Guigo, Roderic and Hamernik, Debora L. and Kappes, Steve M. and Lewin, Harris A. and Lynn, David J. and Nicholas, Frank W. and Reymond, Alexandre and Rijnkels, Monique and Skow, Loren C. and Zdobnov, Evgeny M. and Schook, Lawrence and Womack, James and Alioto, Tyler and Antonarakis, Stylianos E. and Astashyn, Alex and Chapple, Charles E. and Chen, Hsiu-Chuan and Chrast, Jacqueline and Camara, Francisco and Ermolaeva, Olga and Henrichsen, Charlotte N. and Hlavina, Wratko and Kapustin, Yuri and Kiryutin, Boris and Kitts, Paul and Kokocinski, Felix and Landrum, Melissa and Maglott, Donna and Pruitt, Kim and Sapojnikov, Victor and Searle, Stephen M. and Solovyev, Victor and Souvorov, Alexandre and Ucla, Catherine and Wyss, Carine and Anzola, Juan M. and Gerlach, Daniel and Elhaik, Eran and Graur, Dan and Reese, Justin T. and Edgar, Robert C. and Mcewan, John C. and Payne, Gemma M. and Raison, Joy M. and Junier, Thomas and Kriventseva, Evgenia V. and Eyras, Eduardo and Plass, Mireya and Donthu, Ravikiran and Larkin, Denis M. and Reecy, James and Yang, Mary Q. and Chen, Lin and Cheng, Ze and Chitko-Mckown, Carol G. and Liu, George E. and Matukumalli, Lakshmi K. and Song, Jiuzhou and Zhu, Bin and Bradley, Daniel G. and Brinkman, Fiona S. L. and Lau, Lilian P. L. and Whiteside, Matthew D. and Walker, Angela and Wheeler, Thomas T. and Casey, Theresa and German, J. Bruce and Lemay, Danielle G. and Maqbool, Nauman J. and Molenaar, Adrian J. and Seo, Seongwon and Stothard, Paul and Baldwin, Cynthia L. and Baxter, Rebecca and Brinkmeyer-Langford, Candice L. and Brown, Wendy C. and Childers, Christopher P. and Connelley, Timothy and Ellis, Shirley A. and Fritz, Krista and Glass, Elizabeth J. and Herzig, Carolyn T. A. and Iivanainen, Antti and Lahmers, Kevin K. and Bennett, Anna K. and Dickens, C. Michael and Gilbert, James G. R. and Hagen, Darren E. and Salih, Hanni and Aerts, Jan and Caetano, Alexandre R. and Dalrymple, Brian and Garcia, Jose F. and Gill, Clare A. and Hiendleder, Stefan G. and Memili, Erdogan and Spurlock, Diane and Williams, John L. and Alexander, Lee and Brownstein, Michael J. and Guan, Leluo and Holt, Robert A. and Jones, Steven J. M. and Marra, Marco A. and Moore, Richard and Moore, Stephen S. and Roberts, Andy and Taniguchi, Masaaki and Waterman, Richard C. and Chacko, Joseph and Chandrabose, Mimi M. and Cree, Andy and Dao, Marvin D. and Dinh, Huyen H. and Gabisi, Ramatu A. and Hines, Sandra and Hume, Jennifer and Jhangiani, Shalini N. and Joshi, Vandita and Kovar, Christie L. and Lewis, Lora R. and Liu, Yih-Shin and Lopez, John and Morgan, Margaret B. and Nguyen, Ngoc B. and Okwuonu, Geoffrey O. and Ruiz, San J. and Santibanez, Jireh and Wright, Rita A. and Buhay, Christian and Ding, Yan and Dugan-Rocha, Shannon and Herdandez, Judith and Holder, Michael and Sabo, Aniko and Egan, Amy and Goodell, Jason and Wilczek-Boney, Katarzyna and Fowler, Gerald R. and Hitchens, Matthew E. and Lozado, Ryan J. and Moen, Charles and Steffen, David and Warren, James T. and Zhang, Jingkun and Chiu, Readman and Schein, Jacqueline E. and Durbin, K. James and Havlak, Paul and Jiang, Huaiyang and Liu, Yue and Qin, Xiang and Ren, Yanru and Shen, Yufeng and Song, Henry and Bell, Stephanie N. and Davis, Clay and Johnson, Angela J. and Lee, Sandra and Nazareth, Lynne V. and Patel, Bella M. and Pu, Ling-Ling and Vattathil, Selina and Williams, Rex L. and Curry, Stacey and Hamilton, Cerissa and Sodergren, Erica and Wheeler, David A. and Barris, Wes and Bennett, Gary L. and Eggen, Andre and Green, Ronnie D. and Harhay, Gregory P. and Hobbs, Matthew and Jann, Oliver and Keele, John W. and Kent, Matthew P. and Lien, Sigbjorn and Mckay, Stephanie D. and Mcwilliam, Sean and Ratnakumar, Abhirami and Schnabel, Robert D. and Smith, Timothy and Snelling, Warren M. and Sonstegard, Tad S. and Stone, Roger T. and Sugimoto, Yoshikazu and Takasuga, Akiko and Taylor, Jeremy F. and Van Tassell, Curtis P. and Macneil, Michael D. and Abatepaulo, Antonio R. R. and Abbey, Colette A. and Ahola, Virpi and Almeida, Iassudara G. and Amadio, Ariel F. and Anatriello, Elen and Bahadue, Suria M. and Biase, Fernando H. and Boldt, Clayton R. and Carroll, Jeffery A. and Carvalho, Wanessa A. and Cervelatti, Eliane P. and Chacko, Elsa and Chapin, Jennifer E. and Cheng, Ye and Choi, Jungwoo and Colley, Adam J. and de Campos, Tatiana A. and De Donato, Marcos and Santos, Isabel K. and de Oliveira, Carlo J. F. and Deobald, Heather and Devinoy, Eve and Donohue, Kaitlin E. and Dovc, Peter and Eberlein, Annett and Fitzsimmons, Carolyn J. and Franzin, Alessandra M. and Garcia, Gustavo R. and Genini, Sem and Gladney, Cody J. and Grant, Jason R. and Greaser, Marion L. and Green, Jonathan A. and Hadsell, Darryl L. and Hakimov, Hatam A. and Halgren, Rob and Harrow, Jennifer L. and Hart, Elizabeth A. and Hastings, Nicola and Hernandez, Marta and Hu, Zhi-Liang and Ingham, Aaron and Iso-Touru, Terhi and Jamis, Catherine and Jensen, Kirsty and Kapetis, Dimos and Kerr, Tovah and Khalil, Sari S. and Khatib, Hasan and Kolbehdari, Davood and Kumar, Charu G. and Kumar, Dinesh and Leach, Richard and Lee, Justin C. M. and Li, Changxi and Logan, Krystin M. and Malinverni, Roberto and Marques, Elisa and Martin, William F. and Martins, Natalia F. and Maruyama, Sandra R. and Mazza, Raffaele and Mclean, Kim L. and Medrano, Juan F. and Moreno, Barbara T. and More, Daniela D. and Muntean, Carl T. and Nandakumar, Hari P. and Nogueira, Marcelo F. G. and Olsaker, Ingrid and Pant, Sameer D. and Panzitta, Francesca and Pastor, Rosemeire C. P. and Poli, Mario A. and Poslusny, Nathan and Rachagani, Satyanarayana and Ranganathan, Shoba and Razpet, Andrej and Riggs, Penny K. and Rincon, Gonzalo and Rodriguez-Osorio, Nelida and Rodriguez-Zas, Sandra L. and Romero, Natasha E. and Rosenwald, Anne and Sando, Lillian and Schmutz, Sheila M. and Shen, Libing and Sherman, Laura and Southey, Bruce R. and Lutzow, Ylva S. and Sweedler, Jonathan V. and Tammen, Imke and Telugu, Bhanu P. and Urbanski, Jennifer M. and Utsunomiya, Yuri T. and Verschoor, Chris P. and Waardenberg, Ashley J. and Wang, Zhiquan and Ward, Robert and Weikard, Rosemarie and Welsh, Thomas H. and White, Stephen N. and Wilming, Laurens G. and Wunderlich, Kris R. and Yang, Jianqi and Zhao, Feng-Qi}, citeulike-article-id = {4388822}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.1169588}, citeulike-linkout-1 = {http://www.sciencemag.org/cgi/content/abstract/324/5926/522?rss=1}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/19390049}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=19390049}, day = {24}, doi = {10.1126/science.1169588}, issn = {0036-8075}, journal = {Science}, keywords = {agriculture, bovine, cow, genomics, sequence}, month = {April}, number = {5926}, pages = {522--528}, posted-at = {2009-04-24 01:10:26}, priority = {2}, title = {The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution}, url = {http://dx.doi.org/10.1126/science.1169588}, volume = {324}, year = {2009} }

TY - JOUR ID - citeulike:4388822 L3 - citeulike-article-id:4388822 N2 - To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a core set of 14,345 orthologs shared among seven mammalian species of which 1217 are absent or undetected in noneutherian (marsupial or monotreme) genomes. Cattle-specific evolutionary breakpoint regions in chromosomes have a higher density of segmental duplications, enrichment of repetitive elements, and species-specific variations in genes associated with lactation and immune responsiveness. Genes involved in metabolism are generally highly conserved, although five metabolic genes are deleted or extensively diverged from their human orthologs. The cattle genome sequence thus provides a resource for understanding mammalian evolution and accelerating livestock genetic improvement for milk and meat production. 10.1126/science.1169588 IS - 5926 JF - Science SN - 0036-8075 EP - 528 TI - The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution VL - 324 SP - 522 KW - agriculture KW - bovine KW - cow KW - genomics KW - sequence AU - The Bovine Genome Sequencing and Analysis Consortium AU - Elsik, Christine AU - Tellam, Ross AU - Worley, Kim AU - Gibbs, Richard AU - Muzny, Donna AU - Weinstock, George AU - Adelson, David AU - Eichler, Evan AU - Elnitski, Laura AU - Guigo, Roderic AU - Hamernik, Debora AU - Kappes, Steve AU - Lewin, Harris AU - Lynn, David AU - Nicholas, Frank AU - Reymond, Alexandre AU - Rijnkels, Monique AU - Skow, Loren AU - Zdobnov, Evgeny AU - Schook, Lawrence AU - Womack, James AU - Alioto, Tyler AU - Antonarakis, Stylianos AU - Astashyn, Alex AU - Chapple, Charles AU - Chen, Hsiu-Chuan AU - Chrast, Jacqueline AU - Camara, Francisco AU - Ermolaeva, Olga AU - Henrichsen, Charlotte AU - Hlavina, Wratko AU - Kapustin, Yuri AU - Kiryutin, Boris AU - Kitts, Paul AU - Kokocinski, Felix AU - Landrum, Melissa AU - Maglott, Donna AU - Pruitt, Kim AU - Sapojnikov, Victor AU - Searle, Stephen AU - Solovyev, Victor AU - Souvorov, Alexandre AU - Ucla, Catherine AU - Wyss, Carine AU - Anzola, Juan AU - Gerlach, Daniel AU - Elhaik, Eran AU - Graur, Dan AU - Reese, Justin AU - Edgar, Robert AU - Mcewan, John AU - Payne, Gemma AU - Raison, Joy AU - Junier, Thomas AU - Kriventseva, Evgenia AU - Eyras, Eduardo AU - Plass, Mireya AU - Donthu, Ravikiran AU - Larkin, Denis AU - Reecy, James AU - Yang, Mary AU - Chen, Lin AU - Cheng, Ze AU - Chitko-Mckown, Carol AU - Liu, George AU - Matukumalli, Lakshmi AU - Song, Jiuzhou AU - Zhu, Bin AU - Bradley, Daniel AU - Brinkman, Fiona AU - Lau, Lilian AU - Whiteside, Matthew AU - Walker, Angela AU - Wheeler, Thomas AU - Casey, Theresa AU - German, Bruce AU - Lemay, Danielle AU - Maqbool, Nauman AU - Molenaar, Adrian AU - Seo, Seongwon AU - Stothard, Paul AU - Baldwin, Cynthia AU - Baxter, Rebecca AU - Brinkmeyer-Langford, Candice AU - Brown, Wendy AU - Childers, Christopher AU - Connelley, Timothy AU - Ellis, Shirley AU - Fritz, Krista AU - Glass, Elizabeth AU - Herzig, Carolyn AU - Iivanainen, Antti AU - Lahmers, Kevin AU - Bennett, Anna AU - Dickens, Michael AU - Gilbert, James AU - Hagen, Darren AU - Salih, Hanni AU - Aerts, Jan AU - Caetano, Alexandre AU - Dalrymple, Brian AU - Garcia, Jose AU - Gill, Clare AU - Hiendleder, Stefan AU - Memili, Erdogan AU - Spurlock, Diane AU - Williams, John AU - Alexander, Lee AU - Brownstein, Michael AU - Guan, Leluo AU - Holt, Robert AU - Jones, Steven AU - Marra, Marco AU - Moore, Richard AU - Moore, Stephen AU - Roberts, Andy AU - Taniguchi, Masaaki AU - Waterman, Richard AU - Chacko, Joseph AU - Chandrabose, Mimi AU - Cree, Andy AU - Dao, Marvin AU - Dinh, Huyen AU - Gabisi, Ramatu AU - Hines, Sandra AU - Hume, Jennifer AU - Jhangiani, Shalini AU - Joshi, Vandita AU - Kovar, Christie AU - Lewis, Lora AU - Liu, Yih-Shin AU - Lopez, John AU - Morgan, Margaret AU - Nguyen, Ngoc AU - Okwuonu, Geoffrey AU - Ruiz, San AU - Santibanez, Jireh AU - Wright, Rita AU - Buhay, Christian AU - Ding, Yan AU - Dugan-Rocha, Shannon AU - Herdandez, Judith AU - Holder, Michael AU - Sabo, Aniko AU - Egan, Amy AU - Goodell, Jason AU - Wilczek-Boney, Katarzyna AU - Fowler, Gerald AU - Hitchens, Matthew AU - Lozado, Ryan AU - Moen, Charles AU - Steffen, David AU - Warren, James AU - Zhang, Jingkun AU - Chiu, Readman AU - Schein, Jacqueline AU - Durbin, James AU - Havlak, Paul AU - Jiang, Huaiyang AU - Liu, Yue AU - Qin, Xiang AU - Ren, Yanru AU - Shen, Yufeng AU - Song, Henry AU - Bell, Stephanie AU - Davis, Clay AU - Johnson, Angela AU - Lee, Sandra AU - Nazareth, Lynne AU - Patel, Bella AU - Pu, Ling-Ling AU - Vattathil, Selina AU - Williams, Rex AU - Curry, Stacey AU - Hamilton, Cerissa AU - Sodergren, Erica AU - Wheeler, David AU - Barris, Wes AU - Bennett, Gary AU - Eggen, Andre AU - Green, Ronnie AU - Harhay, Gregory AU - Hobbs, Matthew AU - Jann, Oliver AU - Keele, John AU - Kent, Matthew AU - Lien, Sigbjorn AU - Mckay, Stephanie AU - Mcwilliam, Sean AU - Ratnakumar, Abhirami AU - Schnabel, Robert AU - Smith, Timothy AU - Snelling, Warren AU - Sonstegard, Tad AU - Stone, Roger AU - Sugimoto, Yoshikazu AU - Takasuga, Akiko AU - Taylor, Jeremy AU - Van Tassell, Curtis AU - Macneil, Michael AU - Abatepaulo, Antonio AU - Abbey, Colette AU - Ahola, Virpi AU - Almeida, Iassudara AU - Amadio, Ariel AU - Anatriello, Elen AU - Bahadue, Suria AU - Biase, Fernando AU - Boldt, Clayton AU - Carroll, Jeffery AU - Carvalho, Wanessa AU - Cervelatti, Eliane AU - Chacko, Elsa AU - Chapin, Jennifer AU - Cheng, Ye AU - Choi, Jungwoo AU - Colley, Adam AU - de Campos, Tatiana AU - De Donato, Marcos AU - Santos, Isabel AU - de Oliveira, Carlo AU - Deobald, Heather AU - Devinoy, Eve AU - Donohue, Kaitlin AU - Dovc, Peter AU - Eberlein, Annett AU - Fitzsimmons, Carolyn AU - Franzin, Alessandra AU - Garcia, Gustavo AU - Genini, Sem AU - Gladney, Cody AU - Grant, Jason AU - Greaser, Marion AU - Green, Jonathan AU - Hadsell, Darryl AU - Hakimov, Hatam AU - Halgren, Rob AU - Harrow, Jennifer AU - Hart, Elizabeth AU - Hastings, Nicola AU - Hernandez, Marta AU - Hu, Zhi-Liang AU - Ingham, Aaron AU - Iso-Touru, Terhi AU - Jamis, Catherine AU - Jensen, Kirsty AU - Kapetis, Dimos AU - Kerr, Tovah AU - Khalil, Sari AU - Khatib, Hasan AU - Kolbehdari, Davood AU - Kumar, Charu AU - Kumar, Dinesh AU - Leach, Richard AU - Lee, Justin AU - Li, Changxi AU - Logan, Krystin AU - Malinverni, Roberto AU - Marques, Elisa AU - Martin, William AU - Martins, Natalia AU - Maruyama, Sandra AU - Mazza, Raffaele AU - Mclean, Kim AU - Medrano, Juan AU - Moreno, Barbara AU - More, Daniela AU - Muntean, Carl AU - Nandakumar, Hari AU - Nogueira, Marcelo AU - Olsaker, Ingrid AU - Pant, Sameer AU - Panzitta, Francesca AU - Pastor, Rosemeire AU - Poli, Mario AU - Poslusny, Nathan AU - Rachagani, Satyanarayana AU - Ranganathan, Shoba AU - Razpet, Andrej AU - Riggs, Penny AU - Rincon, Gonzalo AU - Rodriguez-Osorio, Nelida AU - Rodriguez-Zas, Sandra AU - Romero, Natasha AU - Rosenwald, Anne AU - Sando, Lillian AU - Schmutz, Sheila AU - Shen, Libing AU - Sherman, Laura AU - Southey, Bruce AU - Lutzow, Ylva AU - Sweedler, Jonathan AU - Tammen, Imke AU - Telugu, Bhanu AU - Urbanski, Jennifer AU - Utsunomiya, Yuri AU - Verschoor, Chris AU - Waardenberg, Ashley AU - Wang, Zhiquan AU - Ward, Robert AU - Weikard, Rosemarie AU - Welsh, Thomas AU - White, Stephen AU - Wilming, Laurens AU - Wunderlich, Kris AU - Yang, Jianqi AU - Zhao, Feng-Qi PY - 2009/04/24/ UR - http://dx.doi.org/10.1126/science.1169588 ER -