Exon Array Analyzer: a web interface for Affymetrix exon array analysis Export

@article{citeulike:6003358, abstract = {Summary: The Exon Array Analyzer (EAA) is a web server, which provides a user-friendly interface to identify alternative splicing events analyzed with Affymetrix Exon Arrays. The EAA implements the Splice Index algorithm to identify differential expressed exons. The use of various filters allows reduction of the number of false positive hits. Results are presented with detailed annotation information and graphics to identify splice events and to facilitate biological validations. To demonstrate the versatility of the EAA, we analyzed exon arrays of 11 different murine tissues using sample data provided by Affymetrix (http://www.affymetrix.com). Data from the heart were compared with other tissues to identify exons that undergo heart-specific alternatively splicing, resulting in the identification of 885 differentially expressed probe sets in 649 genes. Availability: The web interface is available at http://EAA.mpi-bn.mpg.de/. Detailed documentation is available on the EAA web site (http://EAA.mpi-bn.mpg.de/supp.php) including screen shots, example analyzes and step by step instructions. Contact: thomas.braun@mpi-bn.mpg.de Supplementary information: Supplementary data are available at Bioinformatics online. 10.1093/bioinformatics/btp577}, author = {Gellert, Pascal and Uchida, Shizuka and Braun, Thomas}, booktitle = {Bioinformatics}, citeulike-article-id = {6003358}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/bioinformatics/btp577}, citeulike-linkout-1 = {http://bioinformatics.oxfordjournals.org/content/btp577v2/.abstract}, citeulike-linkout-2 = {http://bioinformatics.oxfordjournals.org/content/btp577v2/.full.pdf}, citeulike-linkout-3 = {http://bioinformatics.oxfordjournals.org/cgi/content/abstract/25/24/3323}, citeulike-linkout-4 = {http://view.ncbi.nlm.nih.gov/pubmed/19808879}, citeulike-linkout-5 = {http://www.hubmed.org/display.cgi?uids=19808879}, day = {15}, doi = {10.1093/bioinformatics/btp577}, journal = {Bioinformatics}, keywords = {affymetrix, analysis, exon, microarray, webserver}, month = {December}, number = {24}, pages = {3323--3324}, posted-at = {2009-10-25 01:33:18}, priority = {2}, title = {Exon Array Analyzer: a web interface for Affymetrix exon array analysis}, url = {http://dx.doi.org/10.1093/bioinformatics/btp577}, volume = {25}, year = {2009} }

TY - JOUR ID - citeulike:6003358 L3 - citeulike-article-id:6003358 N2 - Summary: The Exon Array Analyzer (EAA) is a web server, which provides a user-friendly interface to identify alternative splicing events analyzed with Affymetrix Exon Arrays. The EAA implements the Splice Index algorithm to identify differential expressed exons. The use of various filters allows reduction of the number of false positive hits. Results are presented with detailed annotation information and graphics to identify splice events and to facilitate biological validations. To demonstrate the versatility of the EAA, we analyzed exon arrays of 11 different murine tissues using sample data provided by Affymetrix (http://www.affymetrix.com). Data from the heart were compared with other tissues to identify exons that undergo heart-specific alternatively splicing, resulting in the identification of 885 differentially expressed probe sets in 649 genes. Availability: The web interface is available at http://EAA.mpi-bn.mpg.de/. Detailed documentation is available on the EAA web site (http://EAA.mpi-bn.mpg.de/supp.php) including screen shots, example analyzes and step by step instructions. Contact: thomas.braun@mpi-bn.mpg.de Supplementary information: Supplementary data are available at Bioinformatics online. 10.1093/bioinformatics/btp577 IS - 24 JF - Bioinformatics EP - 3324 TI - Exon Array Analyzer: a web interface for Affymetrix exon array analysis VL - 25 T2 - Bioinformatics SP - 3323 KW - affymetrix KW - analysis KW - exon KW - microarray KW - webserver AU - Gellert, Pascal AU - Uchida, Shizuka AU - Braun, Thomas PY - 2009/12/15/ UR - http://dx.doi.org/10.1093/bioinformatics/btp577 ER -