STITCH 2: an interaction network database for small molecules and proteins Export

@article{citeulike:6086691, abstract = {Over the last years, the publicly available knowledge on interactions between small molecules and proteins has been steadily increasing. To create a network of interactions, STITCH aims to integrate the data dispersed over the literature and various databases of biological pathways, drug-target relationships and binding affinities. In STITCH 2, the number of relevant interactions is increased by incorporation of BindingDB, PharmGKB and the Comparative Toxicogenomics Database. The resulting network can be explored interactively or used as the basis for large-scale analyses. To facilitate links to other chemical databases, we adopt InChIKeys that allow identification of chemicals with a short, checksum-like string. STITCH 2.0 connects proteins from 630 organisms to over 74 000 different chemicals, including 2200 drugs. STITCH can be accessed at http://stitch.embl.de/. 10.1093/nar/gkp937}, author = {Kuhn, Michael and Szklarczyk, Damian and Franceschini, Andrea and Campillos, Monica and von Mering, Christian and Jensen, Lars J. and Beyer, Andreas and Bork, Peer}, citeulike-article-id = {6086691}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/nar/gkp937}, citeulike-linkout-1 = {http://nar.oxfordjournals.org/content/gkp937v1/.abstract}, citeulike-linkout-2 = {http://nar.oxfordjournals.org/content/gkp937v1/.full.pdf}, citeulike-linkout-3 = {http://nar.oxfordjournals.org/cgi/content/abstract/38/suppl_1/D552}, citeulike-linkout-4 = {http://view.ncbi.nlm.nih.gov/pubmed/19897548}, citeulike-linkout-5 = {http://www.hubmed.org/display.cgi?uids=19897548}, day = {1}, doi = {10.1093/nar/gkp937}, issn = {1362-4962}, journal = {Nucl. Acids Res.}, keywords = {database, interaction, network, protein-ligand, protein-protein, stitch}, month = {January}, number = {suppl\_1}, pages = {D552--556}, posted-at = {2009-11-08 22:18:17}, priority = {2}, title = {STITCH 2: an interaction network database for small molecules and proteins}, url = {http://dx.doi.org/10.1093/nar/gkp937}, volume = {38}, year = {2010} }

TY - JOUR ID - citeulike:6086691 L3 - citeulike-article-id:6086691 N2 - Over the last years, the publicly available knowledge on interactions between small molecules and proteins has been steadily increasing. To create a network of interactions, STITCH aims to integrate the data dispersed over the literature and various databases of biological pathways, drug-target relationships and binding affinities. In STITCH 2, the number of relevant interactions is increased by incorporation of BindingDB, PharmGKB and the Comparative Toxicogenomics Database. The resulting network can be explored interactively or used as the basis for large-scale analyses. To facilitate links to other chemical databases, we adopt InChIKeys that allow identification of chemicals with a short, checksum-like string. STITCH 2.0 connects proteins from 630 organisms to over 74 000 different chemicals, including 2200 drugs. STITCH can be accessed at http://stitch.embl.de/. 10.1093/nar/gkp937 IS - suppl_1 JF - Nucl. Acids Res. SN - 1362-4962 EP - 556 TI - STITCH 2: an interaction network database for small molecules and proteins VL - 38 SP - D552 KW - database KW - interaction KW - network KW - protein-ligand KW - protein-protein KW - stitch AU - Kuhn, Michael AU - Szklarczyk, Damian AU - Franceschini, Andrea AU - Campillos, Monica AU - von Mering, Christian AU - Jensen, Lars AU - Beyer, Andreas AU - Bork, Peer PY - 2010/01/01/ UR - http://dx.doi.org/10.1093/nar/gkp937 ER -