The Ensembl automatic gene annotation system. Export

@article{curwen04, abstract = {As more genomes are sequenced, there is an increasing need for automated first-pass annotation which allows timely access to important genomic information. The Ensembl gene-building system enables fast automated annotation of eukaryotic genomes. It annotates genes based on evidence derived from known protein, cDNA, and EST sequences. The gene-building system rests on top of the core Ensembl (MySQL) database schema and Perl Application Programming Interface (API), and the data generated are accessible through the Ensembl genome browser (http://www.ensembl.org). To date, the Ensembl predicted gene sets are available for the A. gambiae, C. briggsae, zebrafish, mouse, rat, and human genomes and have been heavily relied upon in the publication of the human, mouse, rat, and A. gambiae genome sequence analysis. Here we describe in detail the gene-building system and the algorithms involved. All code and data are freely available from http://www.ensembl.org.}, author = {Curwen, Val and Eyras, Eduardo and Andrews, T. Daniel and Clarke, Laura and Mongin, Emmanuel and Searle, Steven M. and Clamp, Michele}, citeulike-article-id = {392826}, citeulike-linkout-0 = {http://dx.doi.org/10.1101/gr.1858004}, citeulike-linkout-1 = {http://genome.cshlp.org/content/14/5/942.abstract}, citeulike-linkout-2 = {http://genome.cshlp.org/content/14/5/942.full.pdf}, citeulike-linkout-3 = {http://www.genome.org/cgi/content/abstract/14/5/942}, citeulike-linkout-4 = {http://view.ncbi.nlm.nih.gov/pubmed/15123590}, citeulike-linkout-5 = {http://www.hubmed.org/display.cgi?uids=15123590}, day = {1}, doi = {10.1101/gr.1858004}, issn = {1088-9051}, journal = {Genome research}, keywords = {annot}, month = {May}, number = {5}, pages = {942--950}, posted-at = {2008-02-29 16:58:22}, priority = {2}, title = {The Ensembl automatic gene annotation system.}, url = {http://dx.doi.org/10.1101/gr.1858004}, volume = {14}, year = {2004} }

TY - JOUR ID - curwen04 L3 - citeulike-article-id:392826 N2 - As more genomes are sequenced, there is an increasing need for automated first-pass annotation which allows timely access to important genomic information. The Ensembl gene-building system enables fast automated annotation of eukaryotic genomes. It annotates genes based on evidence derived from known protein, cDNA, and EST sequences. The gene-building system rests on top of the core Ensembl (MySQL) database schema and Perl Application Programming Interface (API), and the data generated are accessible through the Ensembl genome browser (http://www.ensembl.org). To date, the Ensembl predicted gene sets are available for the A. gambiae, C. briggsae, zebrafish, mouse, rat, and human genomes and have been heavily relied upon in the publication of the human, mouse, rat, and A. gambiae genome sequence analysis. Here we describe in detail the gene-building system and the algorithms involved. All code and data are freely available from http://www.ensembl.org. IS - 5 JF - Genome research SN - 1088-9051 EP - 950 TI - The Ensembl automatic gene annotation system. VL - 14 SP - 942 KW - annot AU - Curwen, Val AU - Eyras, Eduardo AU - Andrews, Daniel AU - Clarke, Laura AU - Mongin, Emmanuel AU - Searle, Steven AU - Clamp, Michele PY - 2004/05/01/ UR - http://dx.doi.org/10.1101/gr.1858004 ER -