The neural basis for categorization in semantic memory. Export

@article{citeulike:846218, abstract = {We asked young adults to categorize written object descriptions into one of two categories, based on a rule or on overall similarity, while we monitored regional brain activity with functional magnetic resonance imaging (fMRI). We found significantly greater recruitment of left dorsolateral prefrontal cortex for rule-based categorization in direct comparison with similarity-based categorization. Recruitment of right ventral frontal cortex and thalamus was uniquely associated with rule-based categorization as well. These observations lend support to the claim that executive functions such as working memory, inhibitory control, and selective attention contribute to rule-based categorization. Right inferior parietal activation was uniquely associated with similarity-based categorization. This region may play an important role in overall feature configuration that is important for this form of categorization. We found other brain regions recruited for both rule-based and similarity-based categorization: Anterior cingulate cortex may support the implementation of executive functions during situations with competing response alternatives; and left inferior parietal cortex may be related to the integration of feature knowledge about objects represented in modality-specific association cortices. We also administered a degraded-similarity condition where the task of categorizing a written object description was made more difficult by perceptually degrading the stimulus materials. The degraded condition and the rule-based condition, but not the similarity-based condition, were associated with caudate activation. The caudate may support resource demands that are not specific for a particular categorization process. These findings associate partially distinct large-scale neural networks with different forms of categorization in semantic memory.}, address = {Department of Neurology, University of Pennsylvania, Philadelphia, 19104, USA. mgrossma@mail.med.upenn.edu}, author = {Grossman, M. and Smith, E. E. and Koenig, P. and Glosser, G. and DeVita, C. and Moore, P. and McMillan, C.}, citeulike-article-id = {846218}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/12414293}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=12414293}, issn = {1053-8119}, journal = {NeuroImage}, keywords = {fmri, semantics, thalamus}, month = {November}, number = {3}, pages = {1549--1561}, posted-at = {2009-07-02 12:40:47}, priority = {2}, title = {The neural basis for categorization in semantic memory.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/12414293}, volume = {17}, year = {2002} }

TY - JOUR ID - citeulike:846218 L3 - citeulike-article-id:846218 N2 - We asked young adults to categorize written object descriptions into one of two categories, based on a rule or on overall similarity, while we monitored regional brain activity with functional magnetic resonance imaging (fMRI). We found significantly greater recruitment of left dorsolateral prefrontal cortex for rule-based categorization in direct comparison with similarity-based categorization. Recruitment of right ventral frontal cortex and thalamus was uniquely associated with rule-based categorization as well. These observations lend support to the claim that executive functions such as working memory, inhibitory control, and selective attention contribute to rule-based categorization. Right inferior parietal activation was uniquely associated with similarity-based categorization. This region may play an important role in overall feature configuration that is important for this form of categorization. We found other brain regions recruited for both rule-based and similarity-based categorization: Anterior cingulate cortex may support the implementation of executive functions during situations with competing response alternatives; and left inferior parietal cortex may be related to the integration of feature knowledge about objects represented in modality-specific association cortices. We also administered a degraded-similarity condition where the task of categorizing a written object description was made more difficult by perceptually degrading the stimulus materials. The degraded condition and the rule-based condition, but not the similarity-based condition, were associated with caudate activation. The caudate may support resource demands that are not specific for a particular categorization process. These findings associate partially distinct large-scale neural networks with different forms of categorization in semantic memory. IS - 3 JF - NeuroImage SN - 1053-8119 AD - Department of Neurology, University of Pennsylvania, Philadelphia, 19104, USA. mgrossma@mail.med.upenn.edu EP - 1561 TI - The neural basis for categorization in semantic memory. VL - 17 SP - 1549 KW - fmri KW - semantics KW - thalamus AU - Grossman, M AU - Smith, EE AU - Koenig, P AU - Glosser, G AU - DeVita, C AU - Moore, P AU - McMillan, C PY - 2002/11// UR - http://view.ncbi.nlm.nih.gov/pubmed/12414293 ER -