Molecular mechanisms of nociception Export

@article{citeulike:3270944, abstract = {The sensation of pain alerts us to real or impending injury and triggers appropriate protective responses. Unfortunately, pain often outlives its usefulness as a warning system and instead becomes chronic and debilitating. This transition to a chronic phase involves changes within the spinal cord and brain, but there is also remarkable modulation where pain messages are initiated — at the level of the primary sensory neuron. Efforts to determine how these neurons detect pain-producing stimuli of a thermal, mechanical or chemical nature have revealed new signalling mechanisms and brought us closer to understanding the molecular events that facilitate transitions from acute to persistent pain.}, author = {Julius, David and Basbaum, Allan I.}, citeulike-article-id = {3270944}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/35093019}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/413203a0}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/11557989}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=11557989}, day = {13}, doi = {10.1038/35093019}, issn = {0028-0836}, journal = {Nature}, keywords = {nociception, review}, month = {September}, number = {6852}, pages = {203--210}, posted-at = {2008-09-16 04:12:38}, priority = {2}, publisher = {Nature Publishing Group}, title = {Molecular mechanisms of nociception}, url = {http://dx.doi.org/10.1038/35093019}, volume = {413}, year = {2001} }

TY - JOUR ID - citeulike:3270944 L3 - citeulike-article-id:3270944 N2 - The sensation of pain alerts us to real or impending injury and triggers appropriate protective responses. Unfortunately, pain often outlives its usefulness as a warning system and instead becomes chronic and debilitating. This transition to a chronic phase involves changes within the spinal cord and brain, but there is also remarkable modulation where pain messages are initiated — at the level of the primary sensory neuron. Efforts to determine how these neurons detect pain-producing stimuli of a thermal, mechanical or chemical nature have revealed new signalling mechanisms and brought us closer to understanding the molecular events that facilitate transitions from acute to persistent pain. IS - 6852 JF - Nature SN - 0028-0836 EP - 210 TI - Molecular mechanisms of nociception PB - Nature Publishing Group VL - 413 SP - 203 KW - nociception KW - review AU - Julius, David AU - Basbaum, Allan PY - 2001/09/13/ UR - http://dx.doi.org/10.1038/35093019 ER -