The genome sequence of Drosophila melanogaster. Export

@article{citeulike:186930, abstract = {The fly Drosophila melanogaster is one of the most intensively studied organisms in biology and serves as a model system for the investigation of many developmental and cellular processes common to higher eukaryotes, including humans. We have determined the nucleotide sequence of nearly all of the approximately 120-megabase euchromatic portion of the Drosophila genome using a whole-genome shotgun sequencing strategy supported by extensive clone-based sequence and a high-quality bacterial artificial chromosome physical map. Efforts are under way to close the remaining gaps; however, the sequence is of sufficient accuracy and contiguity to be declared substantially complete and to support an initial analysis of genome structure and preliminary gene annotation and interpretation. The genome encodes approximately 13,600 genes, somewhat fewer than the smaller Caenorhabditis elegans genome, but with comparable functional diversity.}, address = {Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA.}, author = {Adams, M. D. and Celniker, S. E. and Holt, R. A. and Evans, C. A. and Gocayne, J. D. and Amanatides, P. G. and Scherer, S. E. and Li, P. W. and Hoskins, R. A. and Galle, R. F. and George, R. A. and Lewis, S. E. and Richards, S. and Ashburner, M. and Henderson, S. N. and Sutton, G. G. and Wortman, J. R. and Yandell, M. D. and Zhang, Q. and Chen, L. X. and Brandon, R. C. and Rogers, Y. H. and Blazej, R. G. and Champe, M. and Pfeiffer, B. D. and Wan, K. H. and Doyle, C. and Baxter, E. G. and Helt, G. and Nelson, C. R. and Gabor, G. L. and Abril, J. F. and Agbayani, A. and An, H. J. and Andrews-Pfannkoch, C. and Baldwin, D. and Ballew, R. M. and Basu, A. and Baxendale, J. and Bayraktaroglu, L. and Beasley, E. M. and Beeson, K. Y. and Benos, P. V. and Berman, B. P. and Bhandari, D. and Bolshakov, S. and Borkova, D. and Botchan, M. R. and Bouck, J. and Brokstein, P. and Brottier, P. and Burtis, K. C. and Busam, D. A. and Butler, H. and Cadieu, E. and Center, A. and Chandra, I. and Cherry, J. M. and Cawley, S. and Dahlke, C. and Davenport, L. B. and Davies, P. and de Pablos, B. and Delcher, A. and Deng, Z. and Mays, A. D. and Dew, I. and Dietz, S. M. and Dodson, K. and Doup, L. E. and Downes, M. and Dugan-Rocha, S. and Dunkov, B. C. and Dunn, P. and Durbin, K. J. and Evangelista, C. C. and Ferraz, C. and Ferriera, S. and Fleischmann, W. and Fosler, C. and Gabrielian, A. E. and Garg, N. S. and Gelbart, W. M. and Glasser, K. and Glodek, A. and Gong, F. and Gorrell, J. H. and Gu, Z. and Guan, P. and Harris, M. and Harris, N. L. and Harvey, D. and Heiman, T. J. and Hernandez, J. R. and Houck, J. and Hostin, D. and Houston, K. A. and Howland, T. J. and Wei, M. H. and Ibegwam, C. and Jalali, M. and Kalush, F. and Karpen, G. H. and Ke, Z. and Kennison, J. A. and Ketchum, K. A. and Kimmel, B. E. and Kodira, C. D. and Kraft, C. and Kravitz, S. and Kulp, D. and Lai, Z. and Lasko, P. and Lei, Y. and Levitsky, A. A. and Li, J. and Li, Z. and Liang, Y. and Lin, X. and Liu, X. and Mattei, B. and McIntosh, T. C. and McLeod, M. P. and McPherson, D. and Merkulov, G. and Milshina, N. V. and Mobarry, C. and Morris, J. and Moshrefi, A. and Mount, S. M. and Moy, M. and Murphy, B. and Murphy, L. and Muzny, D. M. and Nelson, D. L. and Nelson, D. R. and Nelson, K. A. and Nixon, K. and Nusskern, D. R. and Pacleb, J. M. and Palazzolo, M. and Pittman, G. S. and Pan, S. and Pollard, J. and Puri, V. and Reese, M. G. and Reinert, K. and Remington, K. and Saunders, R. D. and Scheeler, F. and Shen, H. and Shue, B. C. and Sid\'{e}n-Kiamos, I. and Simpson, M. and Skupski, M. P. and Smith, T. and Spier, E. and Spradling, A. C. and Stapleton, M. and Strong, R. and Sun, E. and Svirskas, R. and Tector, C. and Turner, R. and Venter, E. and Wang, A. H. and Wang, X. and Wang, Z. Y. and Wassarman, D. A. and Weinstock, G. M. and Weissenbach, J. and Williams, S. M. and WoodageT and Worley, K. C. and Wu, D. and Yang, S. and Yao, Q. A. and Ye, J. and Yeh, R. F. and Zaveri, J. S. and Zhan, M. and Zhang, G. and Zhao, Q. and Zheng, L. and Zheng, X. H. and Zhong, F. N. and Zhong, W. and Zhou, X. and Zhu, S. and Zhu, X. and Smith, H. O. and Gibbs, R. A. and Myers, E. W. and Rubin, G. M. and Venter, J. C.}, citeulike-article-id = {186930}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/10731132}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=10731132}, day = {24}, issn = {0036-8075}, journal = {Science}, keywords = {drosophila, melanogaster}, month = {March}, number = {5461}, pages = {2185--2195}, posted-at = {2007-12-19 01:55:52}, priority = {2}, title = {The genome sequence of Drosophila melanogaster.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/10731132}, volume = {287}, year = {2000} }

TY - JOUR ID - citeulike:186930 L3 - citeulike-article-id:186930 N2 - The fly Drosophila melanogaster is one of the most intensively studied organisms in biology and serves as a model system for the investigation of many developmental and cellular processes common to higher eukaryotes, including humans. We have determined the nucleotide sequence of nearly all of the approximately 120-megabase euchromatic portion of the Drosophila genome using a whole-genome shotgun sequencing strategy supported by extensive clone-based sequence and a high-quality bacterial artificial chromosome physical map. Efforts are under way to close the remaining gaps; however, the sequence is of sufficient accuracy and contiguity to be declared substantially complete and to support an initial analysis of genome structure and preliminary gene annotation and interpretation. The genome encodes approximately 13,600 genes, somewhat fewer than the smaller Caenorhabditis elegans genome, but with comparable functional diversity. IS - 5461 JF - Science SN - 0036-8075 AD - Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA. EP - 2195 TI - The genome sequence of Drosophila melanogaster. VL - 287 SP - 2185 KW - drosophila KW - melanogaster AU - Adams, MD AU - Celniker, SE AU - Holt, RA AU - Evans, CA AU - Gocayne, JD AU - Amanatides, PG AU - Scherer, SE AU - Li, PW AU - Hoskins, RA AU - Galle, RF AU - George, RA AU - Lewis, SE AU - Richards, S AU - Ashburner, M AU - Henderson, SN AU - Sutton, GG AU - Wortman, JR AU - Yandell, MD AU - Zhang, Q AU - Chen, LX AU - Brandon, RC AU - Rogers, YH AU - Blazej, RG AU - Champe, M AU - Pfeiffer, BD AU - Wan, KH AU - Doyle, C AU - Baxter, EG AU - Helt, G AU - Nelson, CR AU - Gabor, GL AU - Abril, JF AU - Agbayani, A AU - An, HJ AU - Andrews-Pfannkoch, C AU - Baldwin, D AU - Ballew, RM AU - Basu, A AU - Baxendale, J AU - Bayraktaroglu, L AU - Beasley, EM AU - Beeson, KY AU - Benos, PV AU - Berman, BP AU - Bhandari, D AU - Bolshakov, S AU - Borkova, D AU - Botchan, MR AU - Bouck, J AU - Brokstein, P AU - Brottier, P AU - Burtis, KC AU - Busam, DA AU - Butler, H AU - Cadieu, E AU - Center, A AU - Chandra, I AU - Cherry, JM AU - Cawley, S AU - Dahlke, C AU - Davenport, LB AU - Davies, P AU - de Pablos, B AU - Delcher, A AU - Deng, Z AU - Mays, AD AU - Dew, I AU - Dietz, SM AU - Dodson, K AU - Doup, LE AU - Downes, M AU - Dugan-Rocha, S AU - Dunkov, BC AU - Dunn, P AU - Durbin, KJ AU - Evangelista, CC AU - Ferraz, C AU - Ferriera, S AU - Fleischmann, W AU - Fosler, C AU - Gabrielian, AE AU - Garg, NS AU - Gelbart, WM AU - Glasser, K AU - Glodek, A AU - Gong, F AU - Gorrell, JH AU - Gu, Z AU - Guan, P AU - Harris, M AU - Harris, NL AU - Harvey, D AU - Heiman, TJ AU - Hernandez, JR AU - Houck, J AU - Hostin, D AU - Houston, KA AU - Howland, TJ AU - Wei, MH AU - Ibegwam, C AU - Jalali, M AU - Kalush, F AU - Karpen, GH AU - Ke, Z AU - Kennison, JA AU - Ketchum, KA AU - Kimmel, BE AU - Kodira, CD AU - Kraft, C AU - Kravitz, S AU - Kulp, D AU - Lai, Z AU - Lasko, P AU - Lei, Y AU - Levitsky, AA AU - Li, J AU - Li, Z AU - Liang, Y AU - Lin, X AU - Liu, X AU - Mattei, B AU - McIntosh, TC AU - McLeod, MP AU - McPherson, D AU - Merkulov, G AU - Milshina, NV AU - Mobarry, C AU - Morris, J AU - Moshrefi, A AU - Mount, SM AU - Moy, M AU - Murphy, B AU - Murphy, L AU - Muzny, DM AU - Nelson, DL AU - Nelson, DR AU - Nelson, KA AU - Nixon, K AU - Nusskern, DR AU - Pacleb, JM AU - Palazzolo, M AU - Pittman, GS AU - Pan, S AU - Pollard, J AU - Puri, V AU - Reese, MG AU - Reinert, K AU - Remington, K AU - Saunders, RD AU - Scheeler, F AU - Shen, H AU - Shue, BC AU - Sidén-Kiamos, I AU - Simpson, M AU - Skupski, MP AU - Smith, T AU - Spier, E AU - Spradling, AC AU - Stapleton, M AU - Strong, R AU - Sun, E AU - Svirskas, R AU - Tector, C AU - Turner, R AU - Venter, E AU - Wang, AH AU - Wang, X AU - Wang, ZY AU - Wassarman, DA AU - Weinstock, GM AU - Weissenbach, J AU - Williams, SM AU - WoodageT AU - Worley, KC AU - Wu, D AU - Yang, S AU - Yao, QA AU - Ye, J AU - Yeh, RF AU - Zaveri, JS AU - Zhan, M AU - Zhang, G AU - Zhao, Q AU - Zheng, L AU - Zheng, XH AU - Zhong, FN AU - Zhong, W AU - Zhou, X AU - Zhu, S AU - Zhu, X AU - Smith, HO AU - Gibbs, RA AU - Myers, EW AU - Rubin, GM AU - Venter, JC PY - 2000/03/24/ UR - http://view.ncbi.nlm.nih.gov/pubmed/10731132 ER -