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This editorial can be considered the preface to the “Ten Simple Rules” series [1–7]. The rules presented here are somewhat philosophical and behavioural rather than concrete suggestions for how to tackle a particular scientific professional activity such as writing a paper or a grant. The thoughts presented are not our own; rather, we condense and annotate some excellent and timeless suggestions made by the mathematician Richard Hamming two decades ago on how to do “first-class research” [8]. As far as we know, the transcript of the Bell Communications Research Colloquium Seminar provided by Dr. Kaiser [8] was never formally published, so that Dr. Hamming's thoughts are not as widely known as they deserve to be. By distilling these thoughts into something that can be thought of as “Ten Simple Rules,” we hope to bring these ideas to broader attention.
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