Cocaine-induced decision-making deficits are mediated by miscoding in basolateral amygdala. Export

@article{citeulike:1447825, abstract = {Addicts and drug-experienced animals have decision-making deficits in reversal-learning tasks and more complex 'gambling' variants. Here we show evidence that these deficits are mediated by persistent encoding of outdated associative information in the basolateral amygdala. Cue-selective neurons in the basolateral amygdala, recorded in cocaine-treated rats, failed to change cue preference during reversal learning. Further, the presence of these neurons was critical to the expression of the reversal-learning deficit in the cocaine-treated rats.}, address = {Department of Anatomy and Neurobiology, University of Maryland School of Medicine, 20 Penn St., HSF-2 S251, Baltimore, Maryland 21201, USA.}, author = {Stalnaker, Thomas A A. and Roesch, Matthew R R. and Franz, Theresa M M. and Calu, Donna J J. and Singh, Teghpal and Schoenbaum, Geoffrey}, citeulike-article-id = {1447825}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nn1931}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nn1931}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/17603478}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=17603478}, day = {1}, doi = {10.1038/nn1931}, issn = {1097-6256}, journal = {Nat Neurosci}, keywords = {080927, jc, minjip}, month = {July}, posted-at = {2008-09-26 07:11:03}, priority = {2}, title = {Cocaine-induced decision-making deficits are mediated by miscoding in basolateral amygdala.}, url = {http://dx.doi.org/10.1038/nn1931}, year = {2007} }

TY - JOUR ID - citeulike:1447825 L3 - citeulike-article-id:1447825 N2 - Addicts and drug-experienced animals have decision-making deficits in reversal-learning tasks and more complex 'gambling' variants. Here we show evidence that these deficits are mediated by persistent encoding of outdated associative information in the basolateral amygdala. Cue-selective neurons in the basolateral amygdala, recorded in cocaine-treated rats, failed to change cue preference during reversal learning. Further, the presence of these neurons was critical to the expression of the reversal-learning deficit in the cocaine-treated rats. JF - Nat Neurosci SN - 1097-6256 AD - Department of Anatomy and Neurobiology, University of Maryland School of Medicine, 20 Penn St., HSF-2 S251, Baltimore, Maryland 21201, USA. TI - Cocaine-induced decision-making deficits are mediated by miscoding in basolateral amygdala. KW - 080927 KW - jc KW - minjip AU - Stalnaker, Thomas A AU - Roesch, Matthew R AU - Franz, Theresa M AU - Calu, Donna J AU - Singh, Teghpal AU - Schoenbaum, Geoffrey PY - 2007/07/01/ UR - http://dx.doi.org/10.1038/nn1931 ER -