ASTD: The Alternative Splicing and Transcript Diversity database. Export

@article{citeulike:4525702, abstract = {The Alternative Splicing and Transcript Diversity database (ASTD) gives access to a vast collection of alternative transcripts that integrate transcription initiation, polyadenylation and splicing variant data. Alternative transcripts are derived from the mapping of transcribed sequences to the complete human, mouse and rat genomes using an extension of the computational pipeline developed for the ASD (Alternative Splicing Database) and ATD (Alternative Transcript Diversity) databases, which are now superseded by ASTD. For the human genome, ASTD identifies splicing variants, transcription initiation variants and polyadenylation variants in 68\%, 68\% and 62\% of the gene set, respectively, consistent with current estimates for transcription variation. Users can access ASTD through a variety of browsing and query tools, including expression state-based queries for the identification of tissue-specific isoforms. Participating laboratories have experimentally validated a subset of ASTD-predicted alternative splice forms and alternative polyadenylation forms that were not previously reported. The ASTD database can be accessed at http://www.ebi.ac.uk/astd.}, author = {Koscielny, Gautier and Le Texier, Vincent and Gopalakrishnan, Chellappa and Kumanduri, Vasudev and Riethoven, Jean-Jack J. and Nardone, Francesco and Stanley, Eleanor and Fallsehr, Christine and Hofmann, Oliver and Kull, Meelis and Harrington, Eoghan and Bou\'{e}, St\'{e}phanie and Eyras, Eduardo and Plass, Mireya and Lopez, Fabrice and Ritchie, William and Moucadel, Virginie and Ara, Takeshi and Pospisil, Heike and Herrmann, Alexander and G Reich, Jens and Guig\'{o}, Roderic and Bork, Peer and Doeberitz, Magnus von Knebel K. and Vilo, Jaak and Hide, Winston and Apweiler, Rolf and Thanaraj, Thangavel Alphonse A. and Gautheret, Daniel}, citeulike-article-id = {4525702}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.ygeno.2008.11.003}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/19059335}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=19059335}, doi = {10.1016/j.ygeno.2008.11.003}, issn = {1089-8646}, journal = {Genomics}, keywords = {alternative\_splicing, databases, mammalian}, month = {March}, number = {3}, pages = {213--220}, posted-at = {2009-11-01 19:42:18}, priority = {2}, title = {ASTD: The Alternative Splicing and Transcript Diversity database.}, url = {http://dx.doi.org/10.1016/j.ygeno.2008.11.003}, volume = {93}, year = {2009} }

TY - JOUR ID - citeulike:4525702 L3 - citeulike-article-id:4525702 N2 - The Alternative Splicing and Transcript Diversity database (ASTD) gives access to a vast collection of alternative transcripts that integrate transcription initiation, polyadenylation and splicing variant data. Alternative transcripts are derived from the mapping of transcribed sequences to the complete human, mouse and rat genomes using an extension of the computational pipeline developed for the ASD (Alternative Splicing Database) and ATD (Alternative Transcript Diversity) databases, which are now superseded by ASTD. For the human genome, ASTD identifies splicing variants, transcription initiation variants and polyadenylation variants in 68%, 68% and 62% of the gene set, respectively, consistent with current estimates for transcription variation. Users can access ASTD through a variety of browsing and query tools, including expression state-based queries for the identification of tissue-specific isoforms. Participating laboratories have experimentally validated a subset of ASTD-predicted alternative splice forms and alternative polyadenylation forms that were not previously reported. The ASTD database can be accessed at http://www.ebi.ac.uk/astd. IS - 3 JF - Genomics SN - 1089-8646 EP - 220 TI - ASTD: The Alternative Splicing and Transcript Diversity database. VL - 93 SP - 213 KW - alternative_splicing KW - databases KW - mammalian AU - Koscielny, Gautier AU - Le Texier, Vincent AU - Gopalakrishnan, Chellappa AU - Kumanduri, Vasudev AU - Riethoven, Jean-Jack AU - Nardone, Francesco AU - Stanley, Eleanor AU - Fallsehr, Christine AU - Hofmann, Oliver AU - Kull, Meelis AU - Harrington, Eoghan AU - Boué, Stéphanie AU - Eyras, Eduardo AU - Plass, Mireya AU - Lopez, Fabrice AU - Ritchie, William AU - Moucadel, Virginie AU - Ara, Takeshi AU - Pospisil, Heike AU - Herrmann, Alexander AU - G Reich, Jens AU - Guigó, Roderic AU - Bork, Peer AU - Doeberitz, Magnus von Knebel AU - Vilo, Jaak AU - Hide, Winston AU - Apweiler, Rolf AU - Thanaraj, Thangavel Alphonse AU - Gautheret, Daniel PY - 2009/03// UR - http://dx.doi.org/10.1016/j.ygeno.2008.11.003 ER -