pablocarb's enzyme [62 articles] Export

Recent papers added to pablocarb's library classified by the tag enzyme. You can also see everyone's enzyme.

	Enzyme (re)design: lessons from natural evolution and computation. [My Copy] Current opinion in chemical biology, Vol. 13, No. 1. (February 2009), pp. 10-18. by John A. Gerlt, Patricia C. Babbitt posted to in-silico evolution enzyme_engineering enzyme by pablocarb on 2009-11-18 13:09:09 as along with 1 person and 1 group qbin1304 Biocatalysis and Biotransformation
	The origin and evolution of modern metabolism [My Copy] The International Journal of Biochemistry & Cell Biology, Vol. 41, No. 2. (February 2009), pp. 285-297. by Gustavo Caetano-Anollés, Liudmila S. Yafremava, Hannah Gee, Derek Caetano-Anollés, Hee S. Kim, Jay E. Mittenthal posted to metabolism evolution enzyme_evolution enzyme by pablocarb on 2009-11-17 13:19:40 as
	Myopic selection of novel information drives evolution [My Copy] Current Opinion in Biotechnology, Vol. 20, No. 4. (21 August 2009), pp. 504-508. by Antoine Danchin posted to synthetic-biology evolution enzyme_evolution enzyme enzy by pablocarb on 2009-11-13 09:57:03 as
	Metabolite and reaction inference based on enzyme specificities [My Copy] Bioinformatics, Vol. 25, No. 22. (15 November 2009), pp. 2975-2982. by M. J. L. de Groot, R. J. P. van Berlo, W. A. van Winden, P. J. T. Verheijen, M. J. T. Reinders, D. de Ridder posted to specificity similarity reaction promiscuity metabolic_networks metaboli enzyme chemical_fingerprints by pablocarb on 2009-11-04 17:31:21 as
	Occurrence of a putative ancient-like isomerase involved in histidine and tryptophan biosynthesis. [My Copy] EMBO reports, Vol. 4, No. 3. (March 2003), pp. 296-300. by Francisco Barona-Gómez, David A. Hodgson posted to promiscuity isomerase evolution enzyme barrel by pablocarb on 2009-11-03 11:17:29 as
	Exploitation of binding energy for catalysis and design [My Copy] Nature, Vol. 461, No. 7268. (29 October 2009), pp. 1300-1304. by Summer B. Thyme, Jordan Jarjour, Ryo Takeuchi, et al.James J. Havranek, Justin Ashworth, Andrew M. Scharenberg, Barry L. Stoddard, David Baker posted to enzyme energy efficiency catalysis binding by pablocarb on 2009-10-29 10:56:46 as along with 4 people paulymer okapi flbarroso yse
	Natural history as a predictor of protein evolvability [My Copy] Protein Engineering, Design and Selection, Vol. 19, No. 10. (1 October 2006), pp. 439-442. by Taryn L. O'Loughlin, Wayne M. Patrick, Ichiro Matsumura posted to evolution enzyme_evolution enzyme by pablocarb on 2009-10-08 14:20:21 as along with 1 person and 2 groups marcius BioinfoCIPF SGU-CIPF
	A Darwinian Process: The Molecular Evolution of Enzymes. [My Copy] Pensamiento: Revista de investigacion en Informacion filosofica, Vol. 64, No. 242. (2008), pp. 771-782. by J. Bertran posted to molecular_evolution evolution enzyme by pablocarb on 2009-10-08 13:35:15 as
	Guidelines for the Functional Analysis of Engineered and Mutant Enzymes [My Copy] In Protein Engineering Handbook (2008) by Dale E. Edmondson, Giovanni Gadda posted to mutant functional_analysis enzyme_engineering enzyme by pablocarb on 2009-10-04 20:58:34 as
	Molecular paleoscience: systems biology from the past. [My Copy] Advances in enzymology and related areas of molecular biology, Vol. 75 (2007) by Steven A. Benner, Slim O. Sassi, Eric A. Gaucher posted to systems_biology paleogenetics evolution enzyme by pablocarb on 2009-10-04 20:06:07 as along with 1 person sbottani
	How Protein Stability and New Functions Trade Off [My Copy] PLoS Comput Biol, Vol. 4, No. 2. (29 February 2008), e1000002. by Nobuhiko Tokuriki, Francois Stricher, Luis Serrano, Dan S. Tawfik posted to stability specificity protein promiscuity mutations function foldx enzyme energy catalytic affinity by pablocarb on 2009-09-30 15:59:00 as along with 4 people GermanErlenkamp pinney orr aalibes
	DIVERGENT EVOLUTION OF ENZYMATIC FUNCTION: Mechanistically Diverse Superfamilies and Functionally Distinct Suprafamilies [My Copy] Annual Review of Biochemistry, Vol. 70, No. 1. (2001), pp. 209-246. by John A. Gerlt, Patricia C. Babbitt posted to superfamily evolution enzyme divergent_evolution directed_evolution by pablocarb on 2009-09-30 14:55:47 as along with 4 people and 2 groups mittinatten ana tny robert structural_bioinformatics Bioinformatics
	Evolution of Enzymatic Activities in the Enolase Superfamily: l-Fuconate Dehydratase from Xanthomonas campestris†,‡ [My Copy] Biochemistry, Vol. 45, No. 49. (1 December 2006), pp. 14582-14597. by Wen S. Yew, Alexander A. Fedorov, Elena V. Fedorov, et al.John F. Rakus, Richard W. Pierce, Steven C. Almo, John A. Gerlt posted to superfamily scaffold evolution enzyme barrel by pablocarb on 2009-09-30 12:54:01 as
	Catalytic Versatility, Stability, and Evolution of the (βα)8-Barrel Enzyme Fold [My Copy] Chemical Reviews, Vol. 105, No. 11. (1 November 2005), pp. 4038-4055. by Reinhard Sterner, Birte Hocker posted to scaffold evolution enzyme catalytic barrel by pablocarb on 2009-09-30 11:57:28 as along with 1 person dfdong
	The role of quaternary structure in ([small beta]/[small alpha])8-barrel proteins: evolutionary happenstance or a higher level of structure-function relationships? [My Copy] Org. Biomol. Chem., Vol. 7, No. 5. (2009), pp. 833-839. by Sean R. A. Devenish, Juliet A. Gerrard posted to strands scaffold quaternary_structure evolution enzyme beta barrel by pablocarb on 2009-09-29 21:15:53 as
	Pathway evolution, structurally speaking. [My Copy] Current opinion in structural biology, Vol. 12, No. 3. (June 2002), pp. 374-382. by Stuart C. Rison, Janet M. Thornton posted to pathway metabolism evolution enzyme by pablocarb on 2009-09-23 14:30:55 as along with 4 people kuhn alexg eweaver bluto
	Evolution of enzymes and pathways for the biosynthesis of cofactors [My Copy] Nat. Prod. Rep., Vol. 24, No. 5. (October 2007), pp. 972-987. by Gemma L. Holliday, Janet M. Thornton, Andree Marquet, et al.Alison G. Smith, Fabrice Rebeille, Ralf Mendel, Heidi L. Schubert, Andrew D. Lawrence, Martin J. Warren posted to pathway evolution enzyme cofactor biosynthesis by pablocarb on 2009-09-23 14:29:05 as along with 3 people ucbcjbm grottenolm gemmalholliday
	Free energy requirement for domain movement of an enzyme. [My Copy] The Journal of biological chemistry, Vol. 275, No. 25. (23 June 2000), pp. 18939-18945. by J. Ishijima, T. Nakai, S. Kawaguchi, K. Hirotsu, S. Kuramitsu posted to enzyme-promis-paper enzyme dynamics by pablocarb on 2009-09-22 10:04:37 as along with 1 person nickolay
	The Enolase Superfamily: A General Strategy for Enzyme-Catalyzed Abstraction of the α-Protons of Carboxylic Acids† [My Copy] Biochemistry, Vol. 35, No. 51. (1 January 1996), pp. 16489-16501. by Patricia C. Babbitt, Miriam S. Hasson, Joseph E. Wedekind, et al.David R. J. Palmer, William C. Barrett, George H. Reed, Ivan Rayment, Dagmar Ringe, George L. Kenyon, John A. Gerlt posted to evolution enzyme-promis-paper enzyme catalytic by pablocarb on 2009-09-22 09:42:00 as along with 1 person and 1 group ThomasKipper Molecular Enzymetechnology and Biochemistry (AG Siebers)
	The relationship between protein structure and function: a comprehensive survey with application to the yeast genome. [My Copy] Journal of molecular biology, Vol. 288, No. 1. (23 April 1999), pp. 147-164. by H. Hegyi, M. Gerstein posted to function fold enzyme by pablocarb on 2009-09-17 14:20:22 as along with 5 people and 1 group MarcoAlvarez Einat eweaver tny siebertm structural_bioinformatics
	Origin and evolution of metabolic pathways [My Copy] Physics of Life Reviews, Vol. 6, No. 1. (March 2009), pp. 23-52. by Renato Fani, Marco Fondi posted to pathways metabolic evolution enzyme by pablocarb on 2009-09-16 18:04:41 as
	Two-fold repeated (betaalpha)4 half-barrels may provide a molecular tool for dual substrate specificity. [My Copy] EMBO reports, Vol. 6, No. 2. (14 February 2005), pp. 134-139. by Jochen Kuper, Catharina Doenges, Matthias Wilmanns posted to scaffold promiscuity evolution enzyme barrel by pablocarb on 2009-09-16 17:04:59 as along with 1 person dfdong
	Directed evolution of new catalytic activity using the \|[alpha]\|/\|[beta]\|-barrel scaffold [My Copy] Nature, Vol. 403, No. 6770. (10 February 2000), pp. 617-622. by Myriam M. Altamirano, Jonathan M. Blackburn, Cristina Aguayo, Alan R. Fersht posted to scaffold enzyme directed_evolution catalysis barrel by pablocarb on 2009-09-16 14:22:31 as
	Establishing wild-type levels of catalytic activity on natural and artificial (Î²Î±)8-barrel protein scaffolds [My Copy] Proceedings of the National Academy of Sciences, Vol. 106, No. 10. (10 March 2009), pp. 3704-3709. by JÃ¶rg Claren, Christoph Malisi, Birte HÃ¶cker, Reinhard Sterner posted to secondary_structure scaffold enzyme directed_evolution catalysis barrel by pablocarb on 2009-09-16 13:59:15 as along with 1 person ygygod
	Directed evolution of a (alpha-beta)8-barrel enzyme to catalyze related reactions in two different metabolic pathways [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, No. 18. (29 August 2000), pp. 9925-9930. by Catharina Jurgens, Alexander Strom, Dennis Wegener, Stefan Hettwer, Matthias Wilmanns, Reinhard Sterner posted to scaffold promiscuity pathways metabolic evolution enzyme directed_evolution catalysis barrel by pablocarb on 2009-09-16 13:35:46 as along with 1 person msuarezdiez
	Enzyme evolution: Design by necessity [My Copy] Nature, Vol. 403, No. 6770. (10 February 2000), pp. 606-607. by Gregory A. Petsko posted to secondary_structure evolution enzyme by pablocarb on 2009-09-16 13:12:28 as
	Enzyme design by chemical modification of protein scaffolds. [My Copy] Current opinion in chemical biology, Vol. 5, No. 6. (December 2001), pp. 696-704. by C. M. Tann, D. Qi, M. D. Distefano posted to synthetic_methods scaffold enzyme engineering biocatalysis by pablocarb on 2009-09-15 18:34:38 as
	A network perspective on the topological importance of enzymes and their phylogenetic conservation. [My Copy] BMC bioinformatics, Vol. 8, No. 1. (2007) by Wei-chung C. Liu, Wen-hsien H. Lin, Andrew J. Davis, Ferenc Jordán, Hsih-te T. Yang, Ming-jing J. Hwang posted to philogeny evolution enzyme by pablocarb on 2009-09-08 12:53:46 as along with 5 people and 1 group shung renatomilani jiny ptrobajo mdstobbe Bioinformatics
	Evolutionarily Conserved Substrate Substructures for Automated Annotation of Enzyme Superfamilies [My Copy] PLoS Comput Biol, Vol. 4, No. 8. (1 August 2008), e1000142. by Ranyee A. Chiang, Andrej Sali, Patricia C. Babbitt posted to superfamily substrate evolution enzyme conservation by pablocarb on 2009-09-08 12:17:05 as along with 2 people and 1 group ucbcjbm stajich Mycology
	Analysis of Catalytic Residues in Enzyme Active Sites [My Copy] Journal of Molecular Biology, Vol. 324, No. 1. (15 November 2002), pp. 105-121. by Gail J. Bartlett, Craig T. Porter, Neera Borkakoti, Janet M. Thornton posted to secondary_structure prediction enzyme-promis-paper enzyme catalytic_residues by pablocarb on 2009-09-03 11:13:41 as along with 4 people barmak7282 baaden chrn tny
	The role of the conserved Lys68:Glu265 intersubunit salt bridge in aspartate aminotransferase kinetics: multiple forced covariant amino acid substitutions in natural variants. [My Copy] Protein science : a publication of the Protein Society*, Vol. 11, No. 5. (May 2002), pp. 1062-1073. by Edgar Deu, Keith A. Koch, Jack F. Kirsch posted to enzyme-promis-paper examples enzyme by pablocarb on 2009-08-28 13:05:09 as
	Alternate-site enzyme promiscuity. [My Copy] Angewandte Chemie (International ed. in English), Vol. 46, No. 45. (2007), pp. 8597-8600. by Andreas Taglieber, Horst Höbenreich, J. Daniel Carballeira, Régis J. Mondière, Manfred T. Reetz posted to enzyme-promis-paper promiscuity enzyme by pablocarb on 2009-08-26 16:19:43 as
	Synthetic biology: new engineering rules for an emerging discipline [My Copy] Mol Syst Biol, Vol. 2 (16 May 2006), pp. msb4100073-E1-msb4100073-E14. by Ernesto Andrianantoandro, Subhayu Basu, David K. Karig, Ron Weiss posted to enzyme-promis-paper synthetic-biology enzyme engineering by pablocarb on 2009-08-26 14:44:36 as along with 19 people quantumbiology abhishek_tiwari sjayanthi druvus gvillar jec105 ClaireFB lenov Synthetic_Biology_Literature sharatjv johncumbers mmt margaritis jrbanga sujaikumar jbchang nicholasflann kevinchannon grahamc
	Designed divergent evolution of enzyme function [My Copy] Nature, Vol. 440, No. 7087. (20 April 2006), pp. 1078-1082. by Yasuo Yoshikuni, Thomas E. Ferrin, Jay D. Keasling posted to enzyme-promis-paper function evolution enzyme engineering by pablocarb on 2009-08-26 13:29:26 as along with 5 people and 2 groups ygygod lingchong marcius tny dbikard BioinfoCIPF SGU-CIPF
	Highly Expressed Genes in Yeast Evolve Slowly [My Copy] Genetics, Vol. 158, No. 2. (1 June 2001), pp. 927-931. by Csaba Pal, Balazs Papp, Laurence D. Hurst posted to evolution enzyme by pablocarb on 2009-08-24 14:11:24 as along with 6 people and 1 group michaelbarton bjorns penka lewbin balicea skumagai Nie
	Questioning our perceptions about evolution of biodegradative enzymes. [My Copy] Current opinion in microbiology, Vol. 12, No. 3. (26 June 2009), pp. 244-251. by Lawrence P. Wackett posted to evolution enzyme by pablocarb on 2009-08-23 17:57:20 as
	Analogous Enzymes: Independent Inventions in Enzyme Evolution [My Copy] Genome Research, Vol. 8, No. 8. (1 August 1998), pp. 779-790. by Michael Y. Galperin, D. Roland Walker, Eugene V. Koonin posted to evolution enzyme by pablocarb on 2009-08-23 17:52:14 as
	Influence of metabolic network structure and function on enzyme evolution. [My Copy] Genome biology, Vol. 7, No. 5. (9 May 2006) by Dennis Vitkup, Peter Kharchenko, Andreas Wagner posted to network metabolic evolution enzyme by pablocarb on 2009-08-23 17:16:10 as along with 6 people daveGerrard michaelbarton chica tny JeremyZucker mdstobbe
	On the Evolution of Biochemical Syntheses. [My Copy] Proc Natl Acad Sci U S A, Vol. 31, No. 6. (June 1945), pp. 153-157. by N. H. Horowitz posted to catalytic enzyme evolution pathway by pablocarb on 2009-07-28 10:40:58 as along with 2 people bluto chaleil
	Catalytic promiscuity and the evolution of new enzymatic activities. [My Copy] Chemistry & biology, Vol. 6, No. 4. (April 1999), pp. 91-105. by P. J. O'Brien, D. Herschlag posted to promiscuity evolution enzyme-promis-paper enzyme catalytic by pablocarb on 2009-07-28 10:36:11 as along with 4 people barmak7282 svandermoten pauldobson betainverse
	A network perspective on the evolution of metabolism by gene duplication. [My Copy] Genome biology, Vol. 8, No. 2. (27 February 2007), R26. by J. J. Díaz-Mejía, E. Pérez-Rueda, L. Segovia posted to enzyme evolution metabolic network by pablocarb on 2009-07-27 15:06:17 as
	Network analysis of metabolic enzyme evolution in Escherichia coli. [My Copy] BMC bioinformatics, Vol. 5 (18 February 2004) by Sara Light, Per Kraulis posted to enzyme evolution promiscuity by pablocarb on 2009-07-27 14:32:06 as along with 8 people and 1 group renatomilani kuhn alexg eweaver tny azuma livingthingdan pekrau livingthing
	Enzyme recruitment in evolution of new function. [My Copy] Annual review of microbiology, Vol. 30 (1976), pp. 409-425. by R. A. Jensen posted to enzyme evolution promiscuity by pablocarb on 2009-07-27 12:53:21 as along with 1 person tny
	Catalytic promiscuity and the divergent evolution of DNA repair enzymes. [My Copy] Chemical reviews, Vol. 106, No. 2. (February 2006), pp. 720-752. by P. J. O'Brien posted to catalytic enzyme promiscuity by pablocarb on 2009-07-27 12:02:39 as
	Emergence of Novel Enzyme Quasi-Species Depends on the Substrate Matrix [My Copy] Journal of Molecular Biology, Vol. 382, No. 1. (26 September 2008), pp. 136-153. by Sanela Kurtovic, Abeer Shokeer, Bengt Mannervik posted to enzyme promiscuity by pablocarb on 2009-07-27 12:01:48 as
	How does an enzyme evolved in vitro compare to naturally occurring homologs possessing the targeted function? Tyrosine aminotransferase from aspartate aminotransferase. [My Copy] Journal of molecular biology, Vol. 327, No. 3. (28 March 2003), pp. 593-608. by S. C. Rothman, J. F. Kirsch posted to enzyme-promis-paper engineering enzyme evolution promiscuity protein by pablocarb on 2009-07-22 10:34:23 as
	Crystal Structure of Maleylacetoacetate Isomerase/Glutathione Transferase Zeta Reveals the Molecular Basis for Its Remarkable Catalytic Promiscuity†,‡ [My Copy] Biochemistry, Vol. 40, No. 6. (1 February 2001), pp. 1567-1576. by Galina Polekhina, Philip G. Board, Anneke C. Blackburn, Michael W. Parker posted to enzyme-promis-paper enzyme promiscuity secondary by pablocarb on 2009-07-07 10:55:32 as
	The chemical versatility of the β–α–β fold: Catalytic promiscuity and divergent evolution in the tautomerase superfamily [My Copy] Cellular and Molecular Life Sciences, Vol. 65, No. 22. (1 November 2008), pp. 3606-3618. by G. Poelarends, V. Veetil, C. Whitman posted to enzyme-promis-paper enzyme promiscuity secondary by pablocarb on 2009-07-07 10:39:05 as
	A study in molecular contingency: glutamine phosphoribosylpyrophosphate amidotransferase is a promiscuous and evolvable phosphoribosylanthranilate isomerase. [My Copy] Journal of molecular biology, Vol. 377, No. 2. (21 March 2008), pp. 323-336. by W. M. Patrick, I. Matsumura posted to enzyme-promis-paper enzyme promiscuity secondary by pablocarb on 2009-07-07 10:38:35 as
	Delineation of xenobiotic substrate sites in rat glutathione S-transferase M1-1. [My Copy] Protein science : a publication of the Protein Society, Vol. 14, No. 10. (October 2005), pp. 2526-2536. by J. L. Hearne, R. F. Colman posted to enzyme promiscuiy secondary by pablocarb on 2009-07-07 10:37:31 as

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enzyme	62
dynamics	59
enzyme-promis-paper	53
network	53
promiscuity	50
evolution	48
prediction	35
systems-biology	32
interactions	22
protein	21
allostery	19
modularity	18
mutations	18
nmr	17
examples	14
function	14
antibodies	14
bioretro	13
metabolic	13
synthetic-biology	12
scaffold	12
database	12
in-silico-mutagenesis	12
barrel	12
catalytic	11
proposal	11
conservation	10
catalysis	10
hot-spots	10
tree-of-life	9
drug	9
entropy	9
toxicity	9
directed_evolution	9
structure	9
svm	8
pathway	8
engineering	8
domain	8
signatures	8
in-silico	8
binding	8
secondary	7
secondary_structure	7
specificity	7
energy	7
clustering	7
epitopes	7
disorder	7
side-chain	7
md	7
structural	6
control	6
interaction	6
bioinformatics	6
systems_biology	6
immunology	5
metabolic_networks	5
qsar	4
software	4
centrality	4
tnf	4
superfamily	4
chemical_fingerprints	4
molecular	3
fold	3
phylogenetics	3
tree	3
force-fields	3
energy-functions	3
foldx	3
antigen-binding	3
philogeny	3
reconstruction	3
affinity	3
systems	3
essential	3
metabolism	3
cooperativity	3
synthesis	3
similarity	3
enzyme_evolution	3
chemoinformatics	3
metabolic_pathways	3
methyl	3
drug_discovery	2
statistics	2
biology	2
gene	2
pathways	2
metabolic_engineering	2
enzyme_engineering	2
flexibility	2
backbone	2
modeling	2
tree_of_life	2
beta	2
metabolics	2
protein_interaction	2
divergent_evolution	2
ontologies	2
feedback	2
genome	2
reaction	2
hubs	2
fingerprint	2
substrate	2
phylogenetic_trees	2
graph	2
enzymes	2
betweenness	2
phylogenetic_reconstruction	2
trimodal	2
alllostery	2
bayesian	2
efficiency	2
kernel	2
evolutionary	2
interface	2
plants	2
fuzzy	2
interactons	1
essay	1
molecular_targets	1
retrieval	1
molecular_evolution	1
generation	1
protein_design	1
stability	1
dyamics	1
diagnosis	1
ipfam	1
language	1
admet	1
example	1
mrna	1
functional_analysis	1
chimera	1
enymes	1
strands	1
duplication	1
participation	1
profiling	1
classification	1
yeast	1
publishing	1
pharmacology	1
cluster	1
signaling	1
microarray	1
kegg	1
paratopes	1
motifs	1
alignment	1
fuzzy_logic	1
interaction_network	1
potentials	1
paleogenetics	1
biocatalysis	1
flux_balance_analysis	1
native_function	1
catalytic_residues	1
compression	1
expression	1
divergent_groups	1
bacteria	1
wiki	1
optimization_theory	1
protein_engineering	1
orthologous	1
mirna	1
adaptation	1
descriptor	1
ms	1
computational_intelligence	1
colocalization	1
robustness	1
gene_essentiality	1
storage	1
knockout	1
docking	1
signal	1
peptide	1
rna	1
hydrophobicity	1
virotherapy	1
cell_signaling	1
ligand	1
protein_networks	1
hiv-1	1
biosynthesis	1
mutant	1
cancer	1
regulatory	1
enzy	1
disease	1
visualization	1
sequence-analysis	1
chemical_similarity	1
quaternary_structure	1
correlation	1
system_biology	1
evolutionay	1
retraction	1
escherichia_coli	1
localization	1
cell	1
alanine-scanning	1
tyrosine	1
genomics	1
drug_resistance	1
horizontal_gene_transfer	1
high_throughput	1
selectivity	1
bioinformatics-tool	1
sensor	1
isomerase	1
metaboli	1
games	1
beta_alpha	1
promiscuiy	1
cofactor	1
sequence	1
fusion	1
synthetic_methods	1
rotamers	1
biomarkers	1
drug_target	1

pablocarb's enzyme [62 articles] Export

pablocarb's tags