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The mechanobiology of brain function

by: William J. Tyler
Nat Rev Neurosci, Vol. 13, No. 12. (20 December 2012), pp. 867-878, doi:10.1038/nrn3383  Key: citeulike:11753384

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Abstract

All cells are influenced by mechanical forces. In the brain, force-generating and load-bearing proteins twist, turn, ratchet, flex, compress, expand and bend to mediate neuronal signalling and plasticity. Although the functions of mechanosensitive proteins have been thoroughly described in classical sensory systems, the effects of


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