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What is the function of the claustrum?by: F. C. Crick, C. Koch
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Notes for this articleIn summary, we suggest that the claustrum may contain specialized mechanisms that permit information to travel widely within its anterior–posterior and ventral–dorsal extent to synchronize different perceptual, cognitive and motor modalities. This postulated intra-claustrum mixing of information would make it quite different from the thalamus, a subcortical structure that also enjoys widespread and reciprocal relations with most cortical regions, but that does not possess any obvious mechanism to directly link its various constitutive nuclei.
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AbstractThe claustrum is a thin, irregular, sheet-like neuronal structure hidden beneath the inner surface of the neocortex in the general region of the insula. Its function is enigmatic. Its anatomy is quite remarkable in that it receives input from almost all regions of cortex and projects back to almost all regions of cortex. We here briefly summarize what is known about the claustrum, speculate on its possible relationship to the processes that give rise to integrated conscious percepts, propose mechanisms that enable information to travel widely within the claustrum and discuss experiments to address these questions.
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