CiteULike: paulschlesinger's bcl-xl [13 articles]

Simultaneous treatment with camptothecin and valproic acid suppresses induction of Bcl-XL and promotes apoptosis of MCF-7 breast cancer cells

Apoptosis

by Yasuhiro Arakawa, Shinobu Saito, Hisashi Yamada, Keisuke Aiba

posted to apoptosis arakaw09pdf bcl-xl cancer cell death suppression by paulschlesinger on 2009-08-06 00:24:19 as

Endogenous association of Bim BH3-only protein with Mcl-1, Bcl-xL and Bcl-2 on mitochondria in human B cells.

European journal of immunology, Vol. 35, No. 3. (March 2005), pp. 971-976.

by P. Gomez-Bougie, R. Bataille, M. Amiot

posted to bcl-2 bcl-xl bim gomez05pdf interaction mcl-1 mitochondria by paulschlesinger on 2009-05-24 02:59:50 as

Molecular basis of Bcl-xL's target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1.

Journal of molecular biology, Vol. 372, No. 1. (7 September 2007), pp. 223-235.

by W. Feng, S. Huang, H. Wu, M. Zhang

posted to bcl-xl beclin bh3 feng07pdf recognition target by paulschlesinger on 2009-05-23 01:05:15 as

along with 1 person emiko

(alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions.

Journal of the American Chemical Society, Vol. 129, No. 1. (10 January 2007), pp. 139-154.

by J. D. Sadowsky, W. D. Fairlie, E. B. Hadley, et al.H. S. Lee, N. Umezawa, Z. Nikolovska-Coleska, S. Wang, D. C. Huang, Y. Tomita, S. H. Gellman

posted to antagonists bcl-xl bh3 domain foldamer inhbition protein-protein sadows09pdf by paulschlesinger on 2009-05-22 21:34:06 as

Connective Tissue Growth Factor Confers Drug Resistance in Breast Cancer through Concomitant Up-regulation of Bcl-xL and cIAP1

Cancer Res, Vol. 69, No. 8. (15 April 2009), pp. 3482-3491.

by Ming-Yang Wang, Pai-Sheng Chen, Ekambaranellore Prakash, et al.Hsing-Chih Hsu, Hsin-Yi Huang, Ming-Tsan Lin, King-Jen Chang, Min-Liang Kuo

posted to bcl-xl connective factor growth increase tissue wang09pdf by paulschlesinger on 2009-04-17 01:49:21 as

BCL-xL Is a Target Gene Regulated by Hypoxia-inducible Factor-1Î±

Journal of Biological Chemistry, Vol. 284, No. 15. (10 April 2009), pp. 10004-10012.

by Ni Chen, Xueqin Chen, Rui Huang, et al.Hao Zeng, Jing Gong, Wentong Meng, Yiping Lu, Fang Zhao, Lin Wang, Qiao Zhou

posted to bcl-xl gene hypoxia induction target by paulschlesinger on 2009-04-04 02:18:25 as

along with 1 person guhjy

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice.

Science (New York, N.Y.), Vol. 267, No. 5203. (10 March 1995), pp. 1506-1510.

by N. Motoyama, F. Wang, K. A. Roth, et al.H. Sawa, K. Nakayama, K. Nakayama, I. Negishi, S. Senju, Q. Zhang, S. Fujii

posted to bcl-xl cell death deficiency hematopoetic massive mice motoya95pdf trangenic by paulschlesinger on 2008-12-31 22:06:19 as

Induction of Noxa sensitizes human colorectal cancer cells expressing Mcl-1 to the small-molecule Bcl-2/Bcl-xL inhibitor, ABT-737.

Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, No. 24. (15 December 2008), pp. 8132-8142.

by K. Okumura, S. Huang, F. A. Sinicrope

posted to bcl-2 bcl-xl cells expression inhibitor noxa okumur08pdf sensitizes to by paulschlesinger on 2008-12-25 00:50:18 as

Small molecule inhibition of the Bcl-X(L)-BH3 protein-protein interaction: proof-of-concept of an in vivo chemopotentiator ABT-737.

Current topics in medicinal chemistry, Vol. 7, No. 10. (2007), pp. 961-965.

by S. R. Stauffer

posted to abt-737 apoptosis bcl-2 bcl-xl inhibtor interactions protein stauff08pdf by paulschlesinger on 2008-11-14 00:52:41 as

Bcl-XL-Templated Assembly of Its Own Protein−Protein Interaction Modulator from Fragments Decorated with Thio Acids and Sulfonyl Azides

J. Am. Chem. Soc. (24 September 2008)

by Xiangdong Hu, Jiazhi Sun, Hong-Gang Wang, Roman Manetsch

posted to bcl-xl binding hu08pdf modulator template by paulschlesinger on 2008-09-25 00:20:23 as

along with 1 person higueruelo

Bcl-xL and UVRAG Cause a Monomer-Dimer Switch in Beclin1

J. Biol. Chem., Vol. 283, No. 38. (19 September 2008), pp. 26274-26282.

by Christian G. Noble, Jing-Ming Dong, Edward Manser, Haiwei Song

posted to apoptosis bcl-xl beclin-1 noble08pdf by paulschlesinger on 2008-09-22 18:27:56 as

along with 1 person keating

Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein.

The Journal of biological chemistry, Vol. 277, No. 13. (29 March 2002), pp. 11345-11351.

by X. M. Sun, S. B. Bratton, M. Butterworth, M. MacFarlane, G. M. Cohen

posted to apoptosis bcl-2 bcl-xl mitochondria sun08pdf by paulschlesinger on 2008-09-22 17:59:59 as

Role of protein flexibility in the design of Bcl-X(L) targeting agents: insight from molecular dynamics.

Journal of computer-aided molecular design (9 September 2008)

by William Novak, Hongming Wang, Goran Krilov

posted to bcl-xl novak08pdf simulation target by paulschlesinger on 2008-09-11 01:14:27 as

along with 2 people LamBras higueruelo

	Simultaneous treatment with camptothecin and valproic acid suppresses induction of Bcl-XL and promotes apoptosis of MCF-7 breast cancer cells [My Copy] Apoptosis by Yasuhiro Arakawa, Shinobu Saito, Hisashi Yamada, Keisuke Aiba posted to apoptosis arakaw09pdf bcl-xl cancer cell death suppression by paulschlesinger on 2009-08-06 00:24:19 as
	Endogenous association of Bim BH3-only protein with Mcl-1, Bcl-xL and Bcl-2 on mitochondria in human B cells. [My Copy] European journal of immunology, Vol. 35, No. 3. (March 2005), pp. 971-976. by P. Gomez-Bougie, R. Bataille, M. Amiot posted to bcl-2 bcl-xl bim gomez05pdf interaction mcl-1 mitochondria by paulschlesinger on 2009-05-24 02:59:50 as
	Molecular basis of Bcl-xL's target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1. [My Copy] Journal of molecular biology, Vol. 372, No. 1. (7 September 2007), pp. 223-235. by W. Feng, S. Huang, H. Wu, M. Zhang posted to bcl-xl beclin bh3 feng07pdf recognition target by paulschlesinger on 2009-05-23 01:05:15 as along with 1 person emiko
	(alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions. [My Copy] Journal of the American Chemical Society, Vol. 129, No. 1. (10 January 2007), pp. 139-154. by J. D. Sadowsky, W. D. Fairlie, E. B. Hadley, et al.H. S. Lee, N. Umezawa, Z. Nikolovska-Coleska, S. Wang, D. C. Huang, Y. Tomita, S. H. Gellman posted to antagonists bcl-xl bh3 domain foldamer inhbition protein-protein sadows09pdf by paulschlesinger on 2009-05-22 21:34:06 as
	Connective Tissue Growth Factor Confers Drug Resistance in Breast Cancer through Concomitant Up-regulation of Bcl-xL and cIAP1 [My Copy] Cancer Res, Vol. 69, No. 8. (15 April 2009), pp. 3482-3491. by Ming-Yang Wang, Pai-Sheng Chen, Ekambaranellore Prakash, et al.Hsing-Chih Hsu, Hsin-Yi Huang, Ming-Tsan Lin, King-Jen Chang, Min-Liang Kuo posted to bcl-xl connective factor growth increase tissue wang09pdf by paulschlesinger on 2009-04-17 01:49:21 as
	BCL-xL Is a Target Gene Regulated by Hypoxia-inducible Factor-1Î± [My Copy] Journal of Biological Chemistry, Vol. 284, No. 15. (10 April 2009), pp. 10004-10012. by Ni Chen, Xueqin Chen, Rui Huang, et al.Hao Zeng, Jing Gong, Wentong Meng, Yiping Lu, Fang Zhao, Lin Wang, Qiao Zhou posted to bcl-xl gene hypoxia induction target by paulschlesinger on 2009-04-04 02:18:25 as along with 1 person guhjy
	Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. [My Copy] Science (New York, N.Y.), Vol. 267, No. 5203. (10 March 1995), pp. 1506-1510. by N. Motoyama, F. Wang, K. A. Roth, et al.H. Sawa, K. Nakayama, K. Nakayama, I. Negishi, S. Senju, Q. Zhang, S. Fujii posted to bcl-xl cell death deficiency hematopoetic massive mice motoya95pdf trangenic by paulschlesinger on 2008-12-31 22:06:19 as
	Induction of Noxa sensitizes human colorectal cancer cells expressing Mcl-1 to the small-molecule Bcl-2/Bcl-xL inhibitor, ABT-737. [My Copy] Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, No. 24. (15 December 2008), pp. 8132-8142. by K. Okumura, S. Huang, F. A. Sinicrope posted to bcl-2 bcl-xl cells expression inhibitor noxa okumur08pdf sensitizes to by paulschlesinger on 2008-12-25 00:50:18 as
	Small molecule inhibition of the Bcl-X(L)-BH3 protein-protein interaction: proof-of-concept of an in vivo chemopotentiator ABT-737. [My Copy] Current topics in medicinal chemistry, Vol. 7, No. 10. (2007), pp. 961-965. by S. R. Stauffer posted to abt-737 apoptosis bcl-2 bcl-xl inhibtor interactions protein stauff08pdf by paulschlesinger on 2008-11-14 00:52:41 as
	Bcl-XL-Templated Assembly of Its Own Protein−Protein Interaction Modulator from Fragments Decorated with Thio Acids and Sulfonyl Azides [My Copy] J. Am. Chem. Soc. (24 September 2008) by Xiangdong Hu, Jiazhi Sun, Hong-Gang Wang, Roman Manetsch posted to bcl-xl binding hu08pdf modulator template by paulschlesinger on 2008-09-25 00:20:23 as along with 1 person higueruelo
	Bcl-xL and UVRAG Cause a Monomer-Dimer Switch in Beclin1 [My Copy] J. Biol. Chem., Vol. 283, No. 38. (19 September 2008), pp. 26274-26282. by Christian G. Noble, Jing-Ming Dong, Edward Manser, Haiwei Song posted to apoptosis bcl-xl beclin-1 noble08pdf by paulschlesinger on 2008-09-22 18:27:56 as along with 1 person keating
	Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein. [My Copy] The Journal of biological chemistry, Vol. 277, No. 13. (29 March 2002), pp. 11345-11351. by X. M. Sun, S. B. Bratton, M. Butterworth, M. MacFarlane, G. M. Cohen posted to apoptosis bcl-2 bcl-xl mitochondria sun08pdf by paulschlesinger on 2008-09-22 17:59:59 as
	Role of protein flexibility in the design of Bcl-X(L) targeting agents: insight from molecular dynamics. [My Copy] Journal of computer-aided molecular design (9 September 2008) by William Novak, Hongming Wang, Goran Krilov posted to bcl-xl novak08pdf simulation target by paulschlesinger on 2008-09-11 01:14:27 as along with 2 people LamBras higueruelo

paulschlesinger's bcl-xl [13 articles] Export

paulschlesinger's tags

membrane	535
protein	288
apoptosis	213
simulation	158
peptide	126
lipid	116
structure	112
cholesterol	109
binding	102
mitochondria	86
channel	85
cell	80
review	74
diffusion	67
interaction	66
bax	66
bcl-2	62
membranes	61
dynamics	55
fcs	52
pore	52
fusion	51
surface	51
folding	47
bilayer	45
proteins	43
proton	42
activation	41
curvature	40
death	39
molecular	39
analysis	38
transport	38
cells	37
mitochondrial	36
kinetics	35
hydrophobic	35
regulation	34
model	34
micelle	34
phase	33
lateral	33
formation	33
energy	33
receptor	30
peptides	30
cytochrome	28
channels	28
thermodynamics	28
cardiolipin	27
c	27
water	27
tumor	26
mechanism	26
domain	26
bclxl	24
cancer	24
ion	23
family	23
interactions	23
transfer	23
activity	22
acid	22
effect	22
liposome	22
helix	22
toxin	21
tension	21
bim	20
permeability	20
bid	20
bh3	20
vesicles	19
antimicrobial	19
p53	18
amyloid	18
bak	18
metabolism	17
ph	17
transition	17
solution	17
force	17
sterol	16
function	16
melittin	16
oxysterol	16
fluorescence	16
fret	16
calcium	16
biology	15
insertion	15
size	15
rafts	15
modeling	15
nmr	14
interfacial	14
vesicle	14
single	14
aggregation	14
monolayer	14
k	14
fluorescent	13
bcl-xl	13
fluctuations	13
vdac	13
coarse	13
puma	13
free	13
small	13
properties	12
volume	12
molecule	12
mcl-1	12
transmembrane	12
complex	12
phospholipid	12
yeast	12
detergent	12
ceramide	11
amino	11
atp	11
inhibition	11
lysosome	11
oligomerization	11
orientation	11
scattering	11
micelles	11
stability	11
er	11
structural	11
influenza	11
shape	11
fatty	11
two	11
conformational	11
enzyme	11
inhibitor	11
chain	11
pump	11
acids	11
g	11
disease	10
area	10
bilayers	10
pressure	10
liposomes	10
intracellular	10
time	10
cyclodextrin	10
ligand	10
cation	10
stress	10
pi	10
microscopy	10
theory	10
lipids	10
virus	10
voltage	10
expression	10
chloride	10
imaging	10
domains	10
apolipoprotein	9
physics	9
resistance	9
dimerization	9
nanoparticle	9
mutation	9
strucutre	9
crowding	9
transporter	9
line	9
angle	9
flow	9
caspase	9
x-ray	9
conformation	9
bacteria	9
systems	9
stabilization	9
landscape	9
nanoparticles	9
supported	9
in	8
droplets	8
brownian	8
pathway	8
bad	8
red	8
actin	8
resonance	8
heterogeneity	8
tryptophan	8
correlation	8
receptors	8
movement	8
effects	8
scale	8
signalling	8
endocytosis	8
spr	8
osteoclast	8
kinase	8
rhodanese	8
interface	8
surfactant	8
fluctuation	8
targeting	8
endothelial	7
phospholipids	7
translocation	7
cleavage	7
field	7
motion	7
assembly	7
oxidase	7
selectivity	7
spectroscopy	7
gating	7
pores	7
unstructured	7
carlo	7
prion	7
packing	7
plasmon	7
association	7
self	7
md	7
intramembrane	7
thermal	7
active	7
atpase	7
evolution	7
helices	7
behavior	7
crystal	7
entropy	7
monte	7
potassium	7
neutron	7
phospholipase	7
hydration	7
particles	7
viral	7
alpha	6
casimir	6
and	6
order	6
transitions	6
solvent	6
sphingomyelin	6
alzheimer	6
phosphorylation	6
therapy	6
refractive	6
lee08pdf	6
particle	6
state	6
complexes	6
grain	6
concentration	6
beta	6
potential	6
scanning	6
growth	6
surfaces	6
ptp	6
intrinsically	6
nix	6
na	6
critical	6
polymer	6
cytoskeleton	6
calculation	6
der	6
stochastic	6
apoptotic	6
permeabilization	6
hiv	6
mode	6
comparison	6
suppression	6
ternary	6
integration	6
distribution	6
history	6
amphipile	6
bond	6
localization	6
inhibitors	6
anion	6
grained	6
drug	6
adp	6
guv	6
docking	6
gene	6
index	6
composition	6
sds	6
van	6
charge	6
chemistry	6
fission	6
giant	6
mechanics	6
temperature	6
normal	6
long	6
biacore	6
malaria	5
thermodynamic	5
states	5
exchange	5
ising	5
disruption	5
pc	5
flop	5
mesotropic	5
glycine	5
waals	5
elastic	5
separation	5
fluids	5
survival	5
oligomers	5
m2	5
dimer	5
frustration	5
rhomboid	5
synthesis	5
models	5
fas	5
cationic	5
nuclear	5
frap	5
elasticity	5
fluid	5
dsc	5
sensitivity	5
hydrophobicity	5
flip	5
proteases	5
egfr	5
pfob	5
carrier	5
statistical	5
salts	5
inhibit	5
zhang08pdf	5
recognition	5
block	5
caspase-8	5
electrostatic	5
afm	5
signaling	5
proteolysis	5
mice	5
hydrogen	5
deformation	5
lipoprotein	5
bending	5
sequence	5
cl	5
induced	5
inhomogeneous	5
xray	5
cubic	5
quenching	5
cooperativity	5
distance	5
proline	5
degradation	5
quantum	5
multiple	5
mobility	5
osmotic	5
liquid	5
perturbation	5
ripening	5
langmuir	5
zhang09pdf	4
e	4
efflux	4
c-terminal	4
bile	4
based	4
dependent	4
detergents	4
induction	4
lysis	4
adsorption	4
surfactants	4
gramicidin	4
bone	4
electron	4
constant	4
mechanical	4
homology	4
tat	4
sites	4
clc-0	4
changes	4
em	4
omm	4
rapid	4
residues	4
factor	4
energetics	4
lee09pdf	4
clc	4
space	4
action	4
organization	4
pick	4
forces	4
synthase	4
charged	4
gated	4
outer	4
penetration	4
mg	4
interfaces	4
inclusions	4
role	4
molten	4
region	4
like	4
membrne	4
dynamic	4
release	4
environment	4
large	4
sterols	4
tnf	4
oxygen	4
penetrating	4
ostwald	4
multiscale	4
cross	4
measurement	4
wu08pdf	4
langevin	4
optical	4
diabetes	4
fibril	4
electrostatics	4
salt	4
dppc	4
cellular	4
uptake	4
approach	4
anti	4
alanine	4
chemical	4
phases	4
lipase	4
increment	4
gases	4
mismatch	4
disordered	4
phagosome	4
drugs	4
calorimetry	4
of	4
biophysics	4
lifetime	4
kim08pdf	4
globule	4
reconstitution	4
vascular	4
vacuolar	4
signal	4
xiap	4
biosynthesis	4
target	4
system	4
saxs	4
lamellar	4
delivery	4
motif	4
spectra	4
kim09pdf	4
manuscript	4
raft	4
kinetic	4
marsh09pdf	4
ischemia	4
toxicity	4
control	4
crac	4
identification	4
lattice	4
commentary	4
hydrodynamic	4
cardiac	4
wang09pdf	4
incorporation	4
parasite	4
protease	4