Axonal neuropathy in chronic peripheral arterial occlusive disease Export

@article{citeulike:3440206, abstract = {Chronic peripheral arterial occlusive disease of the lower limbs may cause tissue damage. Type and extent of peripheral nerve involvement is controversial. We examined 25 patients with peripheral arterial occlusive disease in various grades of severity and 37 age-matched healthy controls using conventional angiography and motor and sensory nerve conduction tests. Subjects with confounding factors for peripheral neuropathies were excluded. We found prolongation of distal motor latencies, decrease of motor and sensory nerve conduction velocities, and reduction in amplitude of the compound muscle action potential. Amplitudes of the compound muscle action potentials were lower in patients with pain at rest than in patients with intermittent claudication and decreased with increasing neurological disability score. Sural nerve conduction velocity, peroneal nerve F-wave chronodispersion, and tibial nerve F-wave persistence were the most frequent abnormal findings. Therefore we concluded that chronic peripheral arterial occlusive disease causes axonal degeneration, resulting in axonal polyneuropathy. {\copyright} 2002 Wiley Periodicals, Inc. Muscle Nerve 26: 471-476, 2002}, address = {Military Hospital Ulm/Donau, Oberer Eselsberg 40, D-89070 Ulm, Germany}, author = {Weber, Frank and Ziegler, Andrea}, citeulike-article-id = {3440206}, citeulike-linkout-0 = {http://dx.doi.org/10.1002/mus.10235}, citeulike-linkout-1 = {http://www3.interscience.wiley.com/cgi-bin/abstract/97519530/ABSTRACT}, doi = {10.1002/mus.10235}, journal = {Muscle \& Nerve}, keywords = {electrodiagnostics, neuropathy}, number = {4}, pages = {471--476}, posted-at = {2008-10-22 13:58:53}, priority = {2}, title = {Axonal neuropathy in chronic peripheral arterial occlusive disease}, url = {http://dx.doi.org/10.1002/mus.10235}, volume = {26}, year = {2002} }

TY - JOUR ID - citeulike:3440206 L3 - citeulike-article-id:3440206 N2 - Chronic peripheral arterial occlusive disease of the lower limbs may cause tissue damage. Type and extent of peripheral nerve involvement is controversial. We examined 25 patients with peripheral arterial occlusive disease in various grades of severity and 37 age-matched healthy controls using conventional angiography and motor and sensory nerve conduction tests. Subjects with confounding factors for peripheral neuropathies were excluded. We found prolongation of distal motor latencies, decrease of motor and sensory nerve conduction velocities, and reduction in amplitude of the compound muscle action potential. Amplitudes of the compound muscle action potentials were lower in patients with pain at rest than in patients with intermittent claudication and decreased with increasing neurological disability score. Sural nerve conduction velocity, peroneal nerve F-wave chronodispersion, and tibial nerve F-wave persistence were the most frequent abnormal findings. Therefore we concluded that chronic peripheral arterial occlusive disease causes axonal degeneration, resulting in axonal polyneuropathy. © 2002 Wiley Periodicals, Inc. Muscle Nerve 26: 471-476, 2002 IS - 4 JF - Muscle & Nerve AD - Military Hospital Ulm/Donau, Oberer Eselsberg 40, D-89070 Ulm, Germany EP - 476 TI - Axonal neuropathy in chronic peripheral arterial occlusive disease VL - 26 SP - 471 KW - electrodiagnostics KW - neuropathy AU - Weber, Frank AU - Ziegler, Andrea PY - 2002/// UR - http://dx.doi.org/10.1002/mus.10235 ER -