Analysis of organic acids, amino acids, and carnitine in dogs with lipid storage myopathy Export

@article{citeulike:3883116, abstract = {Abnormal accumulations of lipid droplets, localized predominantly in histochemical type 1 fibers, were observed in fresh frozen sections of muscle biopsies from 25 dogs with myalgia, weakness, and muscle atrophy. Compared to controls, lactic acidemia, hyperalaninemia, lactic and pyruvic aciduria, variably increased urinary excretion of carnitine esters, and muscle carnitine deficiency were present. These findings support a metabolic block in oxidative metabolism resulting in lactic acidemia in dogs with lipid storage myopathy. {\copyright} 1998 John Wiley \& Sons, Inc. Muscle Nerve 21:1202-1205, 1998.}, address = {Department of Pathology, School of Medicine, University of California, San Diego, La Jolla, California 92093-0612, USA; Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California 92093-0612, USA; Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, Davis, California, USA; Department of Neurosciences, School of Medicine, University of California, San Diego, La Jolla, California 92093-0612, USA}, author = {Shelton, Diane G. and Nyhan, William L. and Kass, Philip H. and Barshop, Bruce A. and Haas, Richard H.}, citeulike-article-id = {3883116}, citeulike-linkout-0 = {http://dx.doi.org/10.1002/(SICI)1097-4598(199809)21:9%3C1202::AID-MUS13%3E3.0.CO;2-T}, citeulike-linkout-1 = {http://www3.interscience.wiley.com/cgi-bin/abstract/33107/ABSTRACT}, doi = {10.1002/(SICI)1097-4598(199809)21:9%3C1202::AID-MUS13%3E3.0.CO;2-T}, journal = {Muscle \& Nerve}, keywords = {error, inborn, metabolism, myopathy}, number = {9}, pages = {1202--1205}, posted-at = {2009-01-13 18:25:02}, priority = {2}, title = {Analysis of organic acids, amino acids, and carnitine in dogs with lipid storage myopathy}, url = {http://dx.doi.org/10.1002/(SICI)1097-4598(199809)21:9%3C1202::AID-MUS13%3E3.0.CO;2-T}, volume = {21}, year = {1998} }

TY - JOUR ID - citeulike:3883116 L3 - citeulike-article-id:3883116 N2 - Abnormal accumulations of lipid droplets, localized predominantly in histochemical type 1 fibers, were observed in fresh frozen sections of muscle biopsies from 25 dogs with myalgia, weakness, and muscle atrophy. Compared to controls, lactic acidemia, hyperalaninemia, lactic and pyruvic aciduria, variably increased urinary excretion of carnitine esters, and muscle carnitine deficiency were present. These findings support a metabolic block in oxidative metabolism resulting in lactic acidemia in dogs with lipid storage myopathy. © 1998 John Wiley & Sons, Inc. Muscle Nerve 21:1202-1205, 1998. IS - 9 JF - Muscle & Nerve AD - Department of Pathology, School of Medicine, University of California, San Diego, La Jolla, California 92093-0612, USA; Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California 92093-0612, USA; Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, Davis, California, USA; Department of Neurosciences, School of Medicine, University of California, San Diego, La Jolla, California 92093-0612, USA EP - 1205 TI - Analysis of organic acids, amino acids, and carnitine in dogs with lipid storage myopathy VL - 21 SP - 1202 KW - error KW - inborn KW - metabolism KW - myopathy AU - Shelton, Diane AU - Nyhan, William AU - Kass, Philip AU - Barshop, Bruce AU - Haas, Richard PY - 1998/// UR - http://dx.doi.org/10.1002/(SICI)1097-4598(199809)21:9%3C1202::AID-MUS13%3E3.0.CO;2-T ER -