Diagnosis of cerebellar cortical degeneration in a Scottish terrier using magnetic resonance imaging Export

@article{citeulike:4007853, abstract = {Primary cerebellar cortical degeneration (CCD), also termed abiotrophy, is the spontaneous premature degeneration of fully differentiated neurological tissue. Cerebellar hypoplasia shares many morphological features with primary CCD, both conditions being characterised by decreased cerebellar size, with reduced numbers of Purkinje and granular cells. CCD has been identified in many canine breeds. This is the first report of the syndrome in a Scottish terrier. The patient presented with mild, gradually progressive ataxia. Survey radiographs of the cervical spine and cerebrospinal fluid (CSF) analysis were normal. CSF distemper and Toxoplasma titres were negative. A diagnosis of cerebellar atrophy was made based on magnetic resonance imaging. The progressive clinical signs suggested cerebellar degeneration rather than hypoplasia. On necropsy, the cerebellum showed macroscopic and microscopic changes consistent with primary CCD.}, address = {Departments of Companion Animal Medicine, University of Pretoria, Private Bag X04, Onderstepoort 0110, Republic of South Africa; Pathology, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, Republic of South Africa}, author = {van der Merwe, L. L. and Lane, E.}, citeulike-article-id = {4007853}, citeulike-linkout-0 = {http://dx.doi.org/10.1111/j.1748-5827.2001.tb02491.x}, citeulike-linkout-1 = {http://www3.interscience.wiley.com/cgi-bin/abstract/118976329/ABSTRACT}, doi = {10.1111/j.1748-5827.2001.tb02491.x}, journal = {Journal of Small Animal Practice}, keywords = {abiotrophy, cerebellum, mri}, number = {8}, pages = {409--412}, posted-at = {2009-02-04 15:19:36}, priority = {2}, title = {Diagnosis of cerebellar cortical degeneration in a Scottish terrier using magnetic resonance imaging}, url = {http://dx.doi.org/10.1111/j.1748-5827.2001.tb02491.x}, volume = {42}, year = {2001} }

TY - JOUR ID - citeulike:4007853 L3 - citeulike-article-id:4007853 N2 - Primary cerebellar cortical degeneration (CCD), also termed abiotrophy, is the spontaneous premature degeneration of fully differentiated neurological tissue. Cerebellar hypoplasia shares many morphological features with primary CCD, both conditions being characterised by decreased cerebellar size, with reduced numbers of Purkinje and granular cells. CCD has been identified in many canine breeds. This is the first report of the syndrome in a Scottish terrier. The patient presented with mild, gradually progressive ataxia. Survey radiographs of the cervical spine and cerebrospinal fluid (CSF) analysis were normal. CSF distemper and Toxoplasma titres were negative. A diagnosis of cerebellar atrophy was made based on magnetic resonance imaging. The progressive clinical signs suggested cerebellar degeneration rather than hypoplasia. On necropsy, the cerebellum showed macroscopic and microscopic changes consistent with primary CCD. IS - 8 JF - Journal of Small Animal Practice AD - Departments of Companion Animal Medicine, University of Pretoria, Private Bag X04, Onderstepoort 0110, Republic of South Africa; Pathology, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, Republic of South Africa EP - 412 TI - Diagnosis of cerebellar cortical degeneration in a Scottish terrier using magnetic resonance imaging VL - 42 SP - 409 KW - abiotrophy KW - cerebellum KW - mri AU - van der Merwe, LL AU - Lane, E PY - 2001/// UR - http://dx.doi.org/10.1111/j.1748-5827.2001.tb02491.x ER -