Harnessing the immune system to treat cancer. Export

@article{citeulike:1452709, abstract = {A major challenge for the immune system is to recognize and eliminate cells undergoing carcinogenesis. Immune defense against tumors is complex. It can be mediated early by the innate immune system (i.e., phagocytes, NK cells, NKT cells, cytokines, and complement proteins) and later by the adaptive immune system (i.e., B cells and T cells). The eight articles in this Review series on tumor immunology discuss the mechanisms underlying immune surveillance of tumors, the regulation of carcinogenesis by immune inflammatory mediators, current approaches to controlling tumor growth through immunotherapy, and novel targets of immunotherapy.}, address = {Departments of Pathology, Medicine, and Dermatology, New York University School of Medicine, NYU Medical Center, 550 First Avenue, New York, NY 10016, USA. nina.bhardwaj@med.nyu.edu}, author = {Bhardwaj, N.}, citeulike-article-id = {1452709}, citeulike-linkout-0 = {http://dx.doi.org/10.1172/JCI32136}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/17476342}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=17476342}, doi = {10.1172/JCI32136}, issn = {0021-9738}, journal = {J Clin Invest}, keywords = {pathophys}, month = {May}, number = {5}, pages = {1130--1136}, posted-at = {2008-08-24 23:56:41}, priority = {2}, title = {Harnessing the immune system to treat cancer.}, url = {http://dx.doi.org/10.1172/JCI32136}, volume = {117}, year = {2007} }

TY - JOUR ID - citeulike:1452709 L3 - citeulike-article-id:1452709 N2 - A major challenge for the immune system is to recognize and eliminate cells undergoing carcinogenesis. Immune defense against tumors is complex. It can be mediated early by the innate immune system (i.e., phagocytes, NK cells, NKT cells, cytokines, and complement proteins) and later by the adaptive immune system (i.e., B cells and T cells). The eight articles in this Review series on tumor immunology discuss the mechanisms underlying immune surveillance of tumors, the regulation of carcinogenesis by immune inflammatory mediators, current approaches to controlling tumor growth through immunotherapy, and novel targets of immunotherapy. IS - 5 JF - J Clin Invest SN - 0021-9738 AD - Departments of Pathology, Medicine, and Dermatology, New York University School of Medicine, NYU Medical Center, 550 First Avenue, New York, NY 10016, USA. nina.bhardwaj@med.nyu.edu EP - 1136 TI - Harnessing the immune system to treat cancer. VL - 117 SP - 1130 KW - pathophys AU - Bhardwaj, N PY - 2007/05// UR - http://dx.doi.org/10.1172/JCI32136 ER -