Gene Expression Profiles in the Brain Predict Behavior in Individual Honey Bees Export

@article{citeulike:3180612, abstract = {We show that the age-related transition by adult honey bees from hive work to foraging is associated with changes in messenger RNA abundance in the brain for 39\% of [\~{}]5500 genes tested.This result, discovered using a highly replicated experimental design involving 72 microarrays, demonstrates more extensive genomic plasticity in the adult brain than has yet been shown.Experimental manipulations that uncouple behavior and age revealed that messenger RNA changes were primarily associated with behavior.Individual brain messenger RNA profiles correctly predicted the behavior of 57 out of 60 bees, indicating a robust association between brain gene expression in the individual and naturally occurring behavioral plasticity. 10.1126/science.1086807}, author = {Whitfield, Charles W. and Cziko, Anne-Marie and Robinson, Gene E.}, citeulike-article-id = {3180612}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.1086807}, citeulike-linkout-1 = {http://www.sciencemag.org/cgi/content/abstract/302/5643/296}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/14551438}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=14551438}, day = {10}, doi = {10.1126/science.1086807}, journal = {Science}, keywords = {behavior, predict}, month = {October}, number = {5643}, pages = {296--299}, posted-at = {2008-09-02 07:14:38}, priority = {5}, title = {Gene Expression Profiles in the Brain Predict Behavior in Individual Honey Bees}, url = {http://dx.doi.org/10.1126/science.1086807}, volume = {302}, year = {2003} }

TY - JOUR ID - citeulike:3180612 L3 - citeulike-article-id:3180612 N2 - We show that the age-related transition by adult honey bees from hive work to foraging is associated with changes in messenger RNA abundance in the brain for 39% of [~]5500 genes tested.This result, discovered using a highly replicated experimental design involving 72 microarrays, demonstrates more extensive genomic plasticity in the adult brain than has yet been shown.Experimental manipulations that uncouple behavior and age revealed that messenger RNA changes were primarily associated with behavior.Individual brain messenger RNA profiles correctly predicted the behavior of 57 out of 60 bees, indicating a robust association between brain gene expression in the individual and naturally occurring behavioral plasticity. 10.1126/science.1086807 IS - 5643 JF - Science EP - 299 TI - Gene Expression Profiles in the Brain Predict Behavior in Individual Honey Bees VL - 302 SP - 296 KW - behavior KW - predict AU - Whitfield, Charles AU - Cziko, Anne-Marie AU - Robinson, Gene PY - 2003/10/10/ UR - http://dx.doi.org/10.1126/science.1086807 ER -