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Nature biotechnology, Vol. 24, No. 9. (08 September 2006), pp. 1151-1161.
by MAQC Consortium, Leming Shi, Laura H. Reid, et al.Wendell D. Jones, Richard Shippy, Janet A. Warrington, Shawn C. Baker, Patrick J. Collins, Francoise de Longueville, Ernest S. Kawasaki, Kathleen Y. Lee, Yuling Luo, Yongming Andrew A. Sun, James C. Willey, Robert A. Setterquist, Gavin M. Fischer, Weida Tong, Yvonne P. Dragan, David J. Dix, Felix W. Frueh, Frederico M. Goodsaid, Damir Herman, Roderick V. Jensen, Charles D. Johnson, Edward K. Lobenhofer, Raj K. Puri, Uwe Schrf, Jean Thierry-Mieg, Charles Wang, Mike Wilson, Paul K. Wolber, Lu Zhang, Shashi Amur, Wenjun Bao, Catalin C. Barbacioru, Anne Bergstrom B. Lucas, Vincent Bertholet, Cecilie Boysen, Bud Bromley, Donna Brown, Alan Brunner, Roger Canales, Xiaoxi Megan M. Cao, Thomas A. Cebula, James J. Chen, Jing Cheng, Tzu-Ming M. Chu, Eugene Chudin, John Corson, J. Christopher Corton, Lisa J. Croner, Christopher Davies, Timothy S. Davison, Glenda Delenstarr, Xutao Deng, David Dorris, Aron C. Eklund, Xiao-hui H. Fan, Hong Fang, Stephanie Fulmer-Smentek, James C. Fuscoe, Kathryn Gallagher, Weigong Ge, Lei Guo, Xu Guo, Janet Hager, Paul K. Haje, Jing Han, Tao Han, Heather C. Harbottle, Stephen C. Harris, Eli Hatchwell, Craig A. Hauser, Susan Hester, Huixiao Hong, Patrick Hurban, Scott A. Jackson, Hanlee Ji, Charles R. Knight, Winston P. Kuo, J. Eugene LeClerc, Shawn Levy, Quan-Zhen Z. Li, Chunmei Liu, Ying Liu, Michael J. Lombardi, Yunqing Ma, Scott R. Magnuson, Botoul Maqsodi, Tim McDaniel, Nan Mei, Ola Myklebost, Baitang Ning, Natalia Novoradovskaya, Michael S. Orr, Terry W. Osborn, Adam Papallo, Tucker A. Patterson, Roger G. Perkins, Elizabeth H. Peters, Ron Peterson, Kenneth L. Philips, P. Scott Pine, Lajos Pusztai, Feng Qian, Hongzu Ren, Mitch Rosen, Barry A. Rosenzweig, Raymond R. Samaha, Mark Schena, Gary P. Schroth, Svetlana Shchegrova, Dave D. Smith, Frank Staedtler, Zhenqiang Su, Hongmei Sun, Zoltan Szallasi, Zivana Tezak, Danielle Thierry-Mieg, Karol L. Thompson, Irina Tikhonova, Yaron Turpaz, Beena Vallanat, Christophe Van, Stephen J. Walker, Sue Jane J. Wang, Yonghong Wang, Russ Wolfinger, Alex Wong, Jie Wu, Chunlin Xiao, Qian Xie, Jun Xu, Wen Yang, Liang Zhang, Sheng Zhong, Yaping Zong, William Slikker
Abstract
Over the last decade, the introduction of microarray technology has had a profound impact on gene expression research. The publication of studies with dissimilar or altogether contradictory results, obtained using different microarray platforms to analyze identical RNA samples, has raised concerns about the reliability of this technology. The MicroArray Quality Control (MAQC) project was initiated to address these concerns, as well as other performance and data analysis issues. Expression data on four titration pools from two distinct reference RNA samples were ...
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