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Deregulated Expression of EVI1 Defines a Poor Prognostic Subset of MLL-Rearranged Acute Myeloid Leukemias: A Study of the German-Austrian Acute Myeloid Leukemia Study Group and the Dutch-Belgian-Swiss HOVON/SAKK Cooperative Group

by: Stefan Gröschel, Richard F. Schlenk, Jan Engelmann, Veronika Rockova, Veronica Teleanu, Michael W. M. Kühn, Karina Eiwen, Claudia Erpelinck, Marije Havermans, Michael Lübbert, Ulrich Germing, Ingo G. H. Schmidt-Wolf, H. Berna Beverloo, Gerrit J. Schuurhuis, Gert J. Ossenkoppele, Brigitte Schlegelberger, Leo F. Verdonck, Edo Vellenga, Gregor Verhoef, Peter Vandenberghe, Thomas Pabst, Mario Bargetzi, Jürgen Krauter, Arnold Ganser, Peter J. M. Valk, Bob Löwenberg, Konstanze Döhner, Hartmut Döhner, Ruud Delwel
Journal of Clinical Oncology, Vol. 31, No. 1. (01 January 2013), pp. 95-103, doi:10.1200/jco.2011.41.5505  Key: citeulike:11958292

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Abstract

Purpose To evaluate the prognostic value of ecotropic viral integration 1 gene (EVI1) overexpression in acute myeloid leukemia (AML) with MLL gene rearrangements.


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