Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis. Export

@article{citeulike:3732269, abstract = {Although GABAergic interneurons are the main source of synaptic inhibition in the cortex, activation of GABA(A) receptors has been shown to depolarize specific neuronal compartments, resulting in excitation. By using a noninvasive approach to monitor the effect of individual interneurons on the pyramidal cell population, we found that rat hippocampal interneurons hyperpolarized pyramidal cells irrespective of the location of their synapses along the somato-dendritic axis.}, author = {Glickfeld, Lindsey L. and Roberts, J. David and Somogyi, Peter and Scanziani, Massimo}, citeulike-article-id = {3732269}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nn.2230}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/19029887}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=19029887}, day = {23}, doi = {10.1038/nn.2230}, issn = {1546-1726}, journal = {Nature neuroscience}, keywords = {dendrite, hippocampe, inhibitory, interneurone, soma}, month = {January}, number = {1}, pages = {21--23}, posted-at = {2009-05-25 09:01:12}, priority = {2}, title = {Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis.}, url = {http://dx.doi.org/10.1038/nn.2230}, volume = {12}, year = {2009} }

TY - JOUR ID - citeulike:3732269 L3 - citeulike-article-id:3732269 N2 - Although GABAergic interneurons are the main source of synaptic inhibition in the cortex, activation of GABA(A) receptors has been shown to depolarize specific neuronal compartments, resulting in excitation. By using a noninvasive approach to monitor the effect of individual interneurons on the pyramidal cell population, we found that rat hippocampal interneurons hyperpolarized pyramidal cells irrespective of the location of their synapses along the somato-dendritic axis. IS - 1 JF - Nature neuroscience SN - 1546-1726 EP - 23 TI - Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis. VL - 12 SP - 21 KW - dendrite KW - hippocampe KW - inhibitory KW - interneurone KW - soma AU - Glickfeld, Lindsey AU - Roberts, David AU - Somogyi, Peter AU - Scanziani, Massimo PY - 2009/01/23/ UR - http://dx.doi.org/10.1038/nn.2230 ER -