Disruption of thermal perception in a multiple sclerosis patient with central pain. Export

@article{citeulike:5090444, abstract = {OBJECTIVE: To investigate integrative thermal perception in a patient with multiple sclerosis. DESIGN: Quantitative thermosensory testing was used to evaluate pain and other sensations produced by heat, cold, and the thermal grill pain illusion. PATIENT: The authors report on a 43-year-old patient with central pain manifest most strongly in her left arm and hand, contralateral to an upper cervical spinothalamic lesion due to multiple sclerosis. OUTCOME MEASURES AND RESULTS: Quantitative thermosensory testing showed that the patient had heat hypalgesia (no pain with stimuli of 45-50 degrees C) and cold allodynia (pain with innocuous cool temperatures, 25-10 degrees C). Whereas healthy subjects rated 20 degrees and 40 degrees C as nonpainful, but the thermal grill (intermixed 20 and 40 degrees C stimuli) as painful, the patient rated the thermal grill as less painful than 20 degrees C. CONCLUSIONS: The absence of thermal grill-evoked pain is consistent with the hypothesis that in some cases of central pain the loss of the thermosensory pathway results in disruption of the normal cold inhibition of burning pain.}, author = {Morin, C. and Bushnell, M. C. and Luskin, M. B. and Craig, A. D.}, citeulike-article-id = {5090444}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/12048421}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=12048421}, issn = {0749-8047}, journal = {The Clinical journal of pain}, keywords = {disease, grill, illusion, pain, thermal}, number = {3}, pages = {191--195}, posted-at = {2009-07-08 01:30:52}, priority = {2}, title = {Disruption of thermal perception in a multiple sclerosis patient with central pain.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/12048421}, volume = {18}, year = {2002} }

TY - JOUR ID - citeulike:5090444 L3 - citeulike-article-id:5090444 N2 - OBJECTIVE: To investigate integrative thermal perception in a patient with multiple sclerosis. DESIGN: Quantitative thermosensory testing was used to evaluate pain and other sensations produced by heat, cold, and the thermal grill pain illusion. PATIENT: The authors report on a 43-year-old patient with central pain manifest most strongly in her left arm and hand, contralateral to an upper cervical spinothalamic lesion due to multiple sclerosis. OUTCOME MEASURES AND RESULTS: Quantitative thermosensory testing showed that the patient had heat hypalgesia (no pain with stimuli of 45-50 degrees C) and cold allodynia (pain with innocuous cool temperatures, 25-10 degrees C). Whereas healthy subjects rated 20 degrees and 40 degrees C as nonpainful, but the thermal grill (intermixed 20 and 40 degrees C stimuli) as painful, the patient rated the thermal grill as less painful than 20 degrees C. CONCLUSIONS: The absence of thermal grill-evoked pain is consistent with the hypothesis that in some cases of central pain the loss of the thermosensory pathway results in disruption of the normal cold inhibition of burning pain. IS - 3 JF - The Clinical journal of pain SN - 0749-8047 EP - 195 TI - Disruption of thermal perception in a multiple sclerosis patient with central pain. VL - 18 SP - 191 KW - disease KW - grill KW - illusion KW - pain KW - thermal AU - Morin, C AU - Bushnell, MC AU - Luskin, MB AU - Craig, AD PY - 2002///n UR - http://view.ncbi.nlm.nih.gov/pubmed/12048421 ER -