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phcognet's library 1000 articles

 
 

Pharmacognostic and Preliminary Phytochemical Evaluation of the leaves of Bixa orellana

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 7. (April 2010), pp. 132-136
posted to issue7 by phcognet on 2011-05-29 03:29:54 **

Abstract

Various traditional systems of medicine enlightened the importance of the leaves of Bixa orellana (Bixaceae) to have a great medicinal value. The present study was aimed at pharmacognostic and preliminary phytochemical evaluations of B. orellana leaves. The pharmacognostic investigations were carried out in terms of organoleptic, microscopic and physical parameters. The dried leaves were subjected to successive Soxhlet extraction using petroleum ether, chloroform, ethyl acetate, methanol and water. These solvent extracts were subjected to a preliminary phytochemical screening to detect the ...

 

Micromorphological Studies on Gmelina arborea and Clerodendrum serratum

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 7. (April 2010), pp. 137-141
posted to issue7 by phcognet on 2011-05-29 03:29:54 **

Abstract

The crude root drugs of Gmelina arborea Roxb. and Clerodendrum serratum Moon are often adulterated with roots of Gmelina asiatica Linn. and Premna herbacea Roxb. respectively. The present paper provides certain anatomical standards for diagnosing the roots of the afore mentioned original drugs from their adulterants. ...

 

Standardisation of Artemisia annua using Reversed Phase High Performance Liquid Chromatography (RP-HPLC)

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 7. (April 2010), pp. 142-147
posted to issue7 by phcognet on 2011-05-29 03:29:53 **

Abstract

Artemisia annua L is a traditional Chinese medicine for the treatment of many disorders including drug resistant malaria. The active constituent against malaria, artemisinin, has been isolated and characterized by Chinese scientists. Artemisia annua is now being grown in malaria endemic countries like Nigeria. The aim of the present study was to quantify artemisinin content of Nigerian Grown Artemisia annua using a fast and reliable Reversed Phase-High Performance Liquid Chromatography (RP-HPLC) analytical technique since artemisinin content is affected by geographical and ...

 

Biochemical Composition of Seaweeds along Central West Coast of India

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 7. (April 2010), pp. 148-150
posted to issue7 by phcognet on 2011-05-29 03:29:53 **

Abstract

Seaweeds from Asia have a great commercial application as the source of phycocolloides since a very long time. Present investigation reveals biochemical composition of three commonly occurring seaweeds, along the central west coast of India. Seaweeds viz. Ulva fasciata (green), Sargassum ilicifolium (brown) and Gracillaria corticata (red) were analyzed for protein, lipid, carbohydrate, ash and mineral content. S. ilicifolium ranked highest in total protein content among the species analyzed. All species contained approximately 5% crude lipid, although U. fasciata species had ...

 

Screening of Some Coastal Plant Resources for Their Antioxidant Potential, Total Polyphenol and Flavonoid Content. | Pharmacognosy Journal [Phcog J]

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 7. (April 2010), pp. 151-157

Abstract

The methanolic extract of young and mature leaves of nine coastal plants from West coast of Maharshtra were analysed to evaluate free radical scavenging activity. The antioxidant activity was evaluated using 1,1-diphenyl-2-picryl hydrazyl radical (DPPH) and the reductive potential of the methanolic extract. The highest antioxidant activity was recorded in young leaves of Hibiscus tiliaceus (76 %), followed by Syzigium corymbosa (71 %) Calophyllum inophyllum (68 %) and Colubrina asiatica (55 %). The plant species also posseses appreciable reductive potential. The ...

 

In Vitro Antioxidant Activity Of Methanolic Extract Of Rhodiola Imbricata Edgew.

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 7. (April 2010), pp. 157-161

Abstract

Rhodiola imbricata (Roseroot) is a perennial plant distributed in South Asia viz., Pakistan, Nepal, China and India. In India it is endemic to Trans Himalayan cold desert of Ladakh. It is a well known medicinal plant in the Amchi system of medicine (Tibetan system of medicine) being used in various ailments like anti-stress, radio-protective, anticancer, anti-inflammatory agent, adaptogen etc. The aim of this study was to assess the in vitro potential of methanol extract of Rhodiola imbricata roots. The DPPH activity ...

 

Determination of Polyphenolic Content and In-vitro Antioxidant Capacity of the Leaves of Lagenaria siceraria (mol.) standl

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 7. (April 2010), pp. 162-169

Abstract

The leaves of Lagenaria siceraria (bottle gourd), belonging to the family cucurbitaceae being used for the treatment of jaundice and also claimed to be effective in many other diseases. The present research work was under taken to investigate the in-vitro antioxidantactivity of aqueous and ethanolic extracts. The free radicals are capable of independent existence and cause oxidative tissue damage. The therapeutic effects of tannins and flavonoids can be largely attributed to their antioxidant properties. So that the quantitative determinations were undertaken, ...

 

Anti-dermatophyte activity of Cryptolepis buchanani Roem. & Schult

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 7. (April 2010), pp. 170-172

Abstract

The present study was carried to determine antifungal activity of methanol and aqueous extracts of Cryptolepis buchanani Roem. & Schult against human dermatophytic fungi. The in vitro antifungal activity of solvent extracts was carried by Agar well diffusion method. Marked antifungal activity was observed. Methanol extract caused more inhibition of T. rubrum while C. keratinophilum was found to be more sensitive to aqueous extract than other fungi. The preliminary phytochemical analysis showed the presence of phytoconstituents namely saponins, alkaloids and tannins ...

 

Anti-nociceptive and anti-inflammatory activities of Atalantia retusa Merr.

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 7. (April 2010), pp. 173-177

Abstract

Atalantia retusa is an endemic medicinal plant used in the Philippines. Hexane extract from leaves were orally administered on rats and mice and tested using rat paw edema, formalin and writhing assays. Increased pain tolerance was observed in animals administered with the median dose (1.43 mg/Kg BW) in both somatic (P<0.05) and visceral (P<0.01) models by 6.05% and 55.48% better compared to the positive control. The degree of swelling was also reduced by the administration of 1.43 mg/Kg BW at 0.5 ...

 

Evaluation of Antimicrobial activity of stem bark of Ficus bengalensis Linn. Collected from different geographical regions

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 7. (April 2010), pp. 178-180
posted to issue7 by phcognet on 2011-05-29 03:29:53 **

Abstract

The stem bark of Ficus bengalensis is reported to have antimicrobial activity, we planned our work as to evaluate and compare antimicrobial activity of alcoholic extracts of stem bark of F. bengalensis by cup and plate method collected from three different geographical regions viz. Delhi, Gujarat and Uttaranchal. The activity of all the extracts at the dose level 1000 μg/ml, 500 μg/ml and 100 μg/ml were found to be quiet different and all the extracts showed that activity is varied as ...

 

Antibacterial activities of genetic variants of Mirabilis jalapa

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 7. (April 2010), pp. 181-184

Abstract

The aqueous and ethanolic extract derived from the leaves of an indigenous medicinal plant Mirabilis jalapa L (white, cream, yellow and pink, flowered plants) were screened for antibacterial activities against Staphylococcus aureus. Aqueous extracts did not display any inhibition to the tested bacteria. However, the ethanolic extract of only white flowered plant showed good antibacterial activitiy against S. aureus i.e. 54%. While other three colors i.e. cream, yellow, and pink flowered plants extract didn't show any zone of inhibition against the ...

 

Effect Of Hesperidin On Serum Glucose, HbA1c And Oxidative Stress In Myocardial Tissue In Experimentally Induced Myocardial Infarction In Diabetic Rats

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 7. (April 2010), pp. 185-189

Abstract

Present study was designed to evaluate in vitro antioxidant activity in heart and serum Glucose, HbA1c of Hesperidin on isoproterenol induced myocardial infarction in normal and diabetic in rats. Hesperidin (100 mg/kg, p.o) was administered for 28 days in rats injected with single dose of Streptozotocin (65 mg/kg, i.p, STZ) and nicotinamide (110 mg/kg, i.p, NIC) and after isoproterenol (200mg/kg, s.c., ISO) induced myocardial infarction in diabetic rats on 29th and 30th day. At the end of experimental period (i.e. on ...

 

Pharmacognostical And Phytochemical Studies Of Strychnos Potatorum Linn Seeds

  [CiTO]
Pharmacognosy Journal [Phcog J], Vol. 2, No. 8.

Abstract

Introduction: Strychnos potatorum Linn (Fam: Loganiaceae) is a moderate sized tree found in southern and central parts of India, Sri Lanka and Burma. In traditional system of medicine the seeds are used for the treatment of various ailments like jaundice, bronchitis, diabetes, conjunctivitis, chronic diarrhoea, dysentery etc. They are also used to clear muddy water by its coagulant action. Although the seeds are useful in various treatments, its pharmacognostic features and phytochemical analysis were not studied.Methods: The pharmacognosy of the seed ...

 

Phytochemical profile of selected Philippine plants used to treat asthma

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 8. (April 2010), pp. 198-202
posted to issue8 by phcognet on 2011-05-29 03:29:52 **

Abstract

Phytochemical analyses were carried out to determine the similarities of the plant metabolites present in the various plants used traditionally for the alleviation of asthma. Plants were collected from the University of the Philippines Diliman campus. The dried samples were homogenized for overnight soaking in methanol at room temperature. The resulting alcoholic extracts were filtered and concentrated in vacuo and tested for their various metabolites. Saponins, terpenoids, flavonoids and cardiac glycosides were commonly found in the various plant samples and to ...

 

Antibacterial activities of various sequential extracts of Ficus racemosa stem bark

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 8. (April 2010), pp. 203-206
posted to issue8 by phcognet on 2011-05-29 03:29:52 **

Abstract

The present study evaluated the antibacterial activity of sequential extracts of Ficus racemosa stem bark against Staphylococcus aureus [MTCC 3160], Bacillus cereus [MTCC 1306], Pseudomonas aeruginosa [MTCC 1034], Escherichia coli [MTCC 1089] and Bacillus subtilis [MTCC 1133] by disk-diffusion and agar-diffusion methods. In disk-diffusion assay chloroform, acetone and methanol extracts showed moderate antibacterial against Staphylococcus aureus, Bacillus cereus, Bacillus subtilis compared to the positive control, while petroleum ether extract did not exhibit antibacterial activity against any of the organisms tested. Aqueous ...

 

Acute toxicity studies of Some Indian Medicinal plants

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 8. (April 2010), pp. 207-210
posted to issue8 by phcognet on 2011-05-29 03:29:52 **

Abstract

It is presumed that ayurvedic drugs have lesser side effects as compared to allopathic drugs. For the safety to use these plants and preparations (gel and powder forms), the medicinal plants need to be evaluated for their toxicity. The aim of this study was to test the acute toxicity of three medicinal plants, Terminalia bellerica (Gertn.) Roxb. fruits, Moringa pterigosperma (Gaertn) leaves, Cassia tora Linn.leaves. The acute toxicity study was studied on Swiss mice with a dose of 3 and 5 ...

 

Collection and storage of medicinal plants in The Canon of Medicine

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 8. (April 2010), pp. 216-218
posted to issue8 by phcognet on 2011-05-29 03:29:52 **

Abstract

The Canon of Medicine was the reference of medical sciences for many years in western and eastern countries. The second book of this medical encyclopedia is on pharmacology which has a chapter on collection and storage of plant materials. In this work a comparison was done on the Canon of Medicine and modern rules in this area. It seems that Ibn Sina had developed ideas on the condition of plant collection and storage which guaranteed the quality of primary materials. Overall, ...

 

Antioxidant Activity of Fruit Pulp Powder of Cassia fistula

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 8. (April 2010), pp. 219-228
posted to issue8 by phcognet on 2011-05-29 03:29:52 **

Abstract

Fruit pulp powder of Cassia fistula was investigated for its antioxidant activity both in vitro and in vivo. Preliminary phytochemical analysis showed high phenolic and flavone content (22 mg/kg and 4 mg/kg respectively) in pulp. A concentration dependent, increase in FRAP value obtained; suggest high antioxidant property of the extract. In vivo study in young adult mice fed fruit pulp powder extract (100 mg/ kg/BW single dose daily for 30 days) one hour prior to Combination of stresses (immobilization followed by ...

 

Anti-Inflammatory Activity of Leaves of Argyreia Nervosa in Carrageenan-Induced Paw Edema in Rats

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 8. (April 2010), pp. 229-232
posted to issue8 by phcognet on 2011-05-29 03:29:52 **

Abstract

The present study was designed to investigate the anti-inflammatory activity of the water extract of Argyreia nervosa. Inflammatory diseases including different types of rheumatic diseases are very common throughout the world. Therefore the search for a better tolerated anti-inflammatory agent appears to be a necessity. Argyreia nervosa is used as a folk medicine for the treatment of inflammation in India. Present study revealed that the plant Argyreia nervosa possesses a significant anti-inflammatory activity as evidencesd in carrageenan induced paw edema method, ...

 

Pharmacognosy of a local market sample of Parpataka Mollugo cerviana (L.) Ser.

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 8. (April 2010), pp. 233-239
posted to issue8 by phcognet on 2011-05-29 03:29:52 **

Abstract

Parpataka is an important Ayurvedic drug used for the treatment of fevers particularly. The local market sample of Parpataka is identified as Mollugo cerviana (L.) Ser. The botanical, macroscopical, microscopical characters of root, stem, leaf, whole plant macerate, powder analysis, histochemical tests, physical constants and fluorescence studies are presented. ...

 

Pharmacognostical Standardization of Stem Bark of Adenanthera pavonina L.

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 8. (April 2010), pp. 240-246
posted to issue8 by phcognet on 2011-05-29 03:29:52 **

Abstract

Adenanthera pavonina L. syn. Red Sandalwood, (Fabaceae) is an unarmed deciduous tree and and its bark is traditionally used for treatment of various disease conditions in gonorrhea, haematuria, ulcers, it is astringent, vulnerary and aphrodisiac in nature. An attempt has been made to highlight this folk herbal medicine through present study which will assist in standardization for quality, purity and sample identification. Various standardization parameters like morphological characters, microscopic evaluation, physico-chemical evaluations (foreign matter, loss on drying, ash values, extractive values), ...

 

HPTLC Fingerprint Profile Of Some Cinnamomum Species | Pharmacognosy Journal [Phcog J]

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 8. (April 2010), pp. 211-215
posted to issue8 by phcognet on 2011-05-29 03:29:52 **

Abstract

In the present communication, finger print of four medicinally and economically important leaves of Cinnamomum species has been developed. Hexane extract of these plants were developed in the mobile phase of toluene : ethyl acetate (8:1, v/v) and scanned under UV at 254 nm and after dipping in vanillin-sulphuric acid reagent followed by heating at 105°. The four species showed differentiating fingerprints on densitomentric scanning at different wavelengths. These finger prints would be helpful in the authentication of these species. ...

 

Evaluation of Analgesic and Anti-inflammatory Activity of Ficus racemosa Linn. Stem Bark Extract in Rats and Mice

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 6. (February 2010), pp. 65-70
posted to no-tag by phcognet on 2011-05-29 03:29:52 **

Abstract

Present work was undergone to investigate analgesic and anti-inflammatory effect of Ficus racemosa Linn. Stem bark extract in rats and mice. Ficus racemosa Linn. was studied for its analgesic activity on acetic acid induced writhing test in mice, tail flick test in rats and hot plate method in mice. The anti-inflammatory effects were investigated by employing acute inflammatory model i.e carrageenan-induced hind paw oedema, egg albumin induced paw oedema in rats, also studied for its preliminary phytochemical screening and acute toxicity ...

 

Pharmacognostic Screening of Dendrophthoe falcata

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 6, February, 2010., pp. 128-131
posted to no-tag by phcognet on 2011-05-29 03:29:52 **

Abstract

Preliminary pharmacognostical screening of crude drug as well as pet ether, chloroform, ethanol and water extracts were done on Dendrophthoe falcata (Loranthaceae). Dendrophthoe Falcata showed the presence of alkaloids, flavonoids, glycosides, reducing sugar, saponin, terpenoids, tannins and steroids. Morphological and anatomical study has been done with the aim to aid pharmacognostic and taxonomic species using light microscopy. WHO recommended physicochemical determination and authentic phytochemical procedures. Physicochemical, morphological and histological parameters evaluated in this article helps to standardize and authenticate the species ...

 

Comparative Phytochemical and Antibacterial Studies on the bark of Alstonia scholaris R.Br. and Alstonia macrophylla Wall. ex G.Don

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 6. (February 2010), pp. 124-127
posted to no-tag by phcognet on 2011-05-29 03:29:52 **

Abstract

Comparative phytochemical and antibacterial activities of bark of Alstonia scholaris and Alstonia macrophylla were investigated. The successive different solvent extracts showed the presence of alkaloids, phenolics, saponins and tannins were found in both the species. The antibacterial activities of bark of A. scholaris and A. macrophylla in successive different solvent were tested against gram +ve and gram -ve organisms. The chloroform extracts of A. macrophylla showed broader spectrum of antibacterial activity when compared with A. scholaris. However. Alstonia scholaris is widely ...

 

Antioxidative activity and Phytochemical investigation on a High Altitude Medicinal Plant Dracocephalum heterophyllum Benth.

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 6. (February 2010), pp. 112-117
posted to no-tag by phcognet on 2011-05-29 03:29:52 **

Abstract

The antioxidant activity and phytochemical investigation on Dracocephalum heterophyllum Benth. used in the traditional medicine of Ladakh was carried out. The studies on ethnomedicine keenly represent the search for new economic plants for developing modern medicines. The methanol extract was subjected to antioxidative assay using 2,2'- diphenylpicryl-1-hydrazyl (DPPH) and various biochemical tests of aqueous and chloroform extracts were performed. The results indicated that the plant was rich in tannins, flavonoids, saponins, steroids and alkaloids. The free radical scavenging and antioxidant activities ...

 

Antioxidant potential of Trichosanthes dioica Roxb (fruits)

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 6. (February 2010), pp. 107-111
posted to no-tag by phcognet on 2011-05-29 03:29:52 **

Abstract

Objective: The study was undertaken to evaluate the antioxidant activity of fruits of Trichosanthes dioica (Cucurbitaceae) and compared with ascorbic acid (Standard). Materials and Methods: Anti-oxidant activity of aqueous extract of Trichosanthes dioica (TSD) fruits was studied for its free radical scavenging property in different in vitro methods as 1, 1 diphenyl-2- picryl hydrazyl, nitric oxide, reducing power assay and hydrogen peroxide radical method. Different concentrations of aqueous extract of TSD were prepared and evaluated by standard methods. Results: The IC50 ...

 

In vitro antioxidant activity of Entada pursaetha, Toddalia aculeata, and Ziziphus mauritiana.

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 6. (February 2010), pp. 102-106
posted to no-tag by phcognet on 2011-05-29 03:29:52 **

Abstract

The antioxidant activity of the crude methanolic extract of the seeds of Entada pursaetha, the stem of Toddalia aculaeta, and the fruit of Ziziphus mauritiana was investigated. The total phenolic composition of methanolic extract was calculated to be 5.5mg catechol equivalents/g of sample. Antioxidant activity of the extract was evaluated on the basis of ability of scavenging free radical and hydroxyl radical with the Ic 50 values 2.12mg/ml and 1.034mg/ml respectively. Total antioxidant capacity of crude plant extract was found to ...

 

Stability-indicating RP-HPLC determination of Curcumin in Vicco Turmeric cream and Haridrakhand churna.

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 6. (February 2010), pp. 90-101
posted to no-tag by phcognet on 2011-05-29 03:29:52 **

Abstract

A simple, specific, precise and stability-indicating HPLC method of analysis of Curcumin both as a bulk drug and in cream and churna formulations was developed and validated. Chromatographic separation were achieved using Lachrom HPLC with Lichrospher, ODS, (250× 4.6) mm, 5 ? column at ambient temperature. Mixture of ACN: THF: 2%Aceticacid: Water (35: 30: 20:15) was used as mobile phase and delivered at constant flow rate of 0.5 ml/min. 429 nm was selected as wave length for detection of method. The ...

 

Pharmacognostic and Physicochemical investigation of Pterospermum acerifolium Willd leaves (Sterculiaceae)

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 6. (February 2010), pp. 83-89
posted to no-tag by phcognet on 2011-05-29 03:29:52 **

Abstract

Pterospermum acerifolium Willd, a large tree belonging to the family Sterculiaceae, is widely distributed in India particularly in sub-Himalayan tract and outer Himalayan valleys. In present study pharmaconostic and physicochemical investigation of Pterospermum acerifolium has been carried out. Qualitative studies indicated presence of abundant covering and glandular trichomes, anmocytic stomata, 3–5 groups of oval shaped vascular bundles, dorsiventral type of leaf, calcium oxalate crystals, and heavy mucilage present, all physicochemical parameter are studied. These findings will be useful towards establishing pharmacognostic ...

 

Screening of Some Ghanaian Medicinal Plants for Phenolic Compounds and Radical Scavenging Activities

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 6. (February 2010), pp. 201-206
posted to no-tag by phcognet on 2011-05-29 03:29:52 **

Abstract

Extracts from a total of 37 medicinal plants from 15 families were screened for their phenolic compounds and antioxidant activities. Phenolic compounds identified were gallic, vanillic, syringic, caffeic, 2,5-dihydroxybenzoic, rosmarinic and p-coumaric acids. Gallic acid varied from 0.00 – 3.14 g/L, vanillic acid varied from 0.00 – 1.32 g/L, syringic acid varied from 0.00 – 3.40 g/L, caffeic acid varied from 0.00 – 2.04 g/L, 2,5-dihydroxybenzoic acid varied 0.00 – 2.64 g/L, rosmarinic acid varied from 0.00 – 1.90 g/L and ...

 

Standardization of Vaisvanara Churna: A Poly-herbal Formulation

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 5. (January 2010), pp. 1-10
posted to no-tag by phcognet on 2011-05-29 03:29:52 **

Abstract

Cardiospermum halicacabum L. (Sapindaceae) commonly known as 'Balloon vine' is a dioecious, hairy, climbing vine with balloon like clusters of white flowers framed by finely dissected, delicate foliage. The leaf has a bitter taste; the entire plant is used as anti-inflammatory, antibiotic against many bacteria, antiparasitic, antipyretic and as an analgesic. The ethanolic extract of leaves exhibits significant anti-arthritic effect. The present study was therefore carried out to provide requisite pharmacognostic details about the leaf. Pharmacognostic investigation of the leaf and ...

 

Standardization of ” Chopchiniyadi Churna”: An Ayurvedic polyherbal formulation

  [CiTO]
Pharmacognosy Journal, Vol. 2, No. 5. (January 2010), pp. 1-5
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

Standardization of herbal formulations is essential in order to assess the quality, purity, safety and efficacy of drugs based on the amounts of their active principles. The present research work is an attempt to standardize ” Chopchiniyadi Churna” an ayurvedic polyherbal formulation used in the treatment of rheumatism, epilepsy, anthelmintic, malignant ulcers and some diseases of the central nervous system. Three marketed and one in-house formulations were used for the study. All the formulations were standardized on the basis of organoleptic ...

 

Anthelmintic and Antioxidant efficacy of two Macrolichens of Ramalinaceae

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 4. (January 2010), pp. 238-242
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

Lichens and lichen products have been used in traditional medicines for centuries and still hold considerable interest as alternative treatments in various parts of the world. In this study, the anthelmintic and antioxidant efficacy of methanol extract of two macrolichens of Bhadra wildlife sanctuary namely Ramalina hossei H. Magn & G. Awasthi and Ramalina conduplicans Vain. were investigated. Extracts of both lichens exhibited concentration dependent anthelmintic activity as revealed by paralysis and death of adult Indian earth worms. Among lichen extracts, ...

 

Anthelmintic Potential of Andrographis paniculata, Cajanus cajan and Silybum marianum

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 4. (December 2009), pp. 243-245
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

Hydroalcoholic extracts of aerial parts of Andrographis paniculata, Cajanus cajan and Silybum marianum and their combinations were evaluated for anthelmintic properties using Indian adult earthworms (Pheretima posthuma) as a model, as they show physiological and anatomical resemblance with intestinal parasites and round worms. The results were compared with that of standard drug, piperazine citrate. A. paniculata showed better activity (paralysis and death time was 3.33 and 5.16 min respectively at a concentration of 40mg/ml), while its combination (1:1) with S. marianum ...

 

The analytical and toxicological profiles of the red dye from the heart wood of Caesalpinia sappan

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 4. (December 2009), pp. 246-250
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

Three phenolic red pigments were observed in combination from the heart wood of Caesalpinia sappan (F: Caesalpiniaceae). Preliminary cytotoxic and acute toxicity studies indicated that these natural colour pigments were safe compared to the FDC grade coal tar dyes. The isolated colour extract (CSWC) was highly soluble in water and analysed by spectrophotometric and HPTLC methods. ...

 

Preliminary Evaluation of Cassia auriculata Seed Mucilage as Binding Agent

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 4. (December 2009), pp. 251-257
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

Cassia auriculata is a tropical tree locally belonging to the family Caesalpiniaceae found widely in India. Seeds of plant contain gluco-mannose hence attempt to evaluate the seeds for suitability as tablet binder is considered and the present investigation reports the isolation of mucilage of Cassia auriculata seed. The DSC and FTIR thermograms of drug and gum indicated no chemical interaction. Phytochemical characteristics of mucilage, such as carbohydrate, protein and flavanoids etc. were studied. Physiochemical characteristics of mucilage, such as solubility, swelling ...

 

Antioxidant potential of Trichosanthes dioica Roxb (fruits)

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 4. (December 2009), pp. 258-262
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

The study was undertaken to evaluate the antioxidant activity of fruits of Trichosanthes dioica (Cucurbitaceae) and compared with ascorbic acid (Standard). Anti-oxidant activity of aqueous extract of Trichosanthes dioica (TSD) fruits was studied for its free radical scavenging property in different in vitro methods as 1, 1 diphenyl-2- picryl hydrazyl, nitric oxide, reducing power assay and hydrogen peroxide radical method. Different concentrations of aqueous extract of TSD were prepared and evaluated by standard methods. The IC50 values of aqueous extract of ...

 

Comparative Phytochemical and Antibacterial Studies on the bark of Alstonia scholaris R.Br. and Alstonia macrophylla Wall. ex G.Don

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 4. (December 2009), pp. 263-266
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

Comparative phytochemical and antibacterial activities of bark of Alstonia scholaris and Alstonia macrophylla were investigated. The successive different solvent extracts showed the presence of alkaloids, phenolics, saponins and tannins were found in both the species. The antibacterial activities of bark of A. scholaris and A. macrophylla in successive different solvent were tested against gram +ve and gram -ve organisms. The chloroform extracts of A. macrophylla showed broader spectrum of antibacterial activity when compared with A. scholaris. However. Alstonia scholaris is widely ...

 

Pharmacognostic and Physico-Chemical Studies on the Leaves of Cardiospermum halicacabum L.

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 4. (December 2009), pp. 267-272
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

Cardiospermum halicacabum L. (Sapindaceae) commonly known as ” Balloon vine” is a dioecious, hairy, climbing vine with balloon like clusters of white flowers framed by finely dissected, delicate foliage. The leaf has a bitter taste; the entire plant is used as anti-inflammatory, antibiotic against many bacteria, antiparasitic, antipyretic and as an analgesic. The ethanolic extract of leaves exhibits significant anti-arthritic effect. The present study was therefore carried out to provide requisite pharmacognostic details about the leaf. Pharmacognostic investigation of the leaf ...

 

Alpha-Glucosidase Inhibitory and Hypoglycemic Activities of Physalis Minima Extract.

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 4. (December 2009), pp. 273-278
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

Alpha glucosidase in-vitro inhibitory activity and hypoglycemic effect by oral administration in rats of Physalis minima ethanol extracts have been investigated. Physalis minima extract showed in-vitro inhibitory activity of intestinal alpha glucosiadase enzyme maltase. Analysis of data confirms that alpha glucosidase inhibition activity was maximum at 1000mcg/ml of Physalis minima. The purpose of study was to know whether Physalis minima extract could reduce intestinal absorption of monosaccharides by inhibiting disaccharide hydrolysis. The post prandial elevation in blood glucose level at 60 ...

 

In vitro evaluation of anthelmintic activity of anterdhum padhati mashi and bahirdhum padhati mashi of green Cocos nucifera Linn.(Palmae) husk.

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 4. (December 2009), pp. 279-281
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

he aim of present study was to evaluate anthelmintic potential of anterdhum Padhati Mahi (APM) and Bahirdhum Padhati mashi (BPM) using Pheretima posthuma and Ascardia galli as test worms. Various concentrations (10 – 100 mg/ml) of APM and BPM were tested in the bioassay, which involved determination of time of paralysis (P) and time of death (D) of the worms. Piperazine citrate (10 mg/ml) was included as standard reference and distilled water as control. The results of present study indicated that ...

 

A Survey of Medicinal Weed Flora of Wheat (Triticum aestivum L. em.Thell.) Fields in Mahendergarh District of Haryana (India)

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 4. (December 2009), pp. 282-287
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

A total of 19 species of weeds in wheat fields representing 11 families were collected from the different region of Mahendergarh district of Haryana during the winter seasons of November 2007 to April 2008 and November 2008 to April 2009. The survey revealed that a significant number of weed species has an ethnomedicinal value, besides this some weeds are highly nutritious and their leaves may be used as food or herbal medicine. The study suggested that there is a tremendous scope ...

 

Antioxidant Activities of Methanolic and Aqueous Extracts from Leaves of Martynia annua Linn.

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 4. (December 2009), pp. 288-297
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

The antioxidant activity of the methanolic and aqueous extracts of Martynia annua Linn. leaves were evaluated by several in vitro systems of assay, namely, reducing power assay, DPPH radical-scavenging activity, nitric oxide scavenging activity, H2O2 radical scavenging activity, superoxide radical scavenging assay, hydroxyl radical-scavenging activity, and total antioxidant capacity. Total phenolic content was measured by Folin–Ciocalteau reagent. The antioxidant property depends upon concentration and increased with increasing amount of the extract. The free radical scavenging and antioxidant activities may be attributed ...

 

Antifungal and Antiaflatoxigenic activity of Aegle marmelos Linn.

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 4. (December 2009), pp. 298-301
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

Aegle marmelos Linn. (Rutaceae) is reported to possess a number of medicinal properties including antidiarrhoeal, antimicrobial, antifungal and activities. The antiaflatoxigenic effects of ethanolic extract of the leaves of Aegle marmelos were studied on common aflatoxigenic fungal species. Aegle marmelos exhibited antifungal and antiaflatoxigenic activity at a concentration range of 0.5 to 2 mg/ml. The shake flask method was used to evaluate the antifungal and antiaflatoxigenic activity. The extract showed varied levels of antifungal and antiaflatoxigenic activity against the test fungi. ...

 

Screening of Some Ghanaian Medicinal Plants for Phenolic Compounds and Radical Scavenging Activities

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 3. (October 2009), pp. 201-206
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

Extracts from a total of 37 medicinal plants from 15 families were screened for their phenolic compounds and antioxidant activities. Phenolic compounds identified were gallic, vanillic, syringic, caffeic, 2,5-dihydroxybenzoic, rosmarinic and p-coumaric acids. Gallic acid varied from 0.00 – 3.14 g/L, vanillic acid varied from 0.00 – 1.32 g/L, syringic acid varied from 0.00 – 3.40 g/L, caffeic acid varied from 0.00 – 2.04 g/L, 2,5-dihydroxybenzoic acid varied 0.00 – 2.64 g/L, rosmarinic acid varied from 0.00 – 1.90 g/L and ...

 

Screening of Some Ghanaian Medicinal Plants for Phenolic Compounds and Radical Scavenging Activities

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 3. (October 2009), pp. 201-206
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

Extracts from a total of 37 medicinal plants from 15 families were screened for their phenolic compounds and antioxidant activities. Phenolic compounds identified were gallic, vanillic, syringic, caffeic, 2,5-dihydroxybenzoic, rosmarinic and p-coumaric acids. Gallic acid varied from 0.00 – 3.14 g/L, vanillic acid varied from 0.00 – 1.32 g/L, syringic acid varied from 0.00 – 3.40 g/L, caffeic acid varied from 0.00 – 2.04 g/L, 2,5-dihydroxybenzoic acid varied 0.00 – 2.64 g/L, rosmarinic acid varied from 0.00 – 1.90 g/L and ...

 

Pharmacognostical Profiling of Roots of Salacia prenoides L.

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 3. (October 2009), pp. 233-237
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

Salacia prenoides or S.chinensis belonging to the family Hippocrateaceae is a climbing shrub known as saptarangi in Ayurveda. The roots of this plant is repoted to possess various medicinal uses as antidiabetic, astringent and abortificient. The pharmacognostical study of roots of this plant has not been reported. Therefore, the present investigation was planned to study the morphology, microscopy, physicochemical parameters, phytochemical screening and HPTLC study of roots of Salacia prenoides. ...

 

Pharmacognostical Evaluation of Argyreia speciosa (Burm.f.) Bojer.

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 3. (October 2009), pp. 223-232
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

The Present study deals with the detailed pharmacognostical evaluation of Argyreia speciosa (Burm.f.) Bojer. (Convolvulaceae). Morphoanatomy of the root part have been studied with the aim to aid pharmacognostic and taxonomic species identification. The physicochemical, morphological and histological parameters presented in this paper may be proposed as parameters to establish the authenticity of A. speciosa and can possibly help to differentiate the drug from its other species. ...

 

Comparative thin layer chromatographic investigations on sources of Shankhpushpi

  [CiTO]
Pharmacognosy Journal, Vol. 1, No. 3. (October 2009), pp. 224-226
posted to no-tag by phcognet on 2011-05-29 03:29:51 **

Abstract

The aim of the present study was to investigate the different plant sources of Shankhpushpi viz., Evolvulus alsinoides Linn. (EA), Convulvulus pluricaulis Choisy. (CP), Canscora decussata Schult. (CD) and Clitorea ternatea Linn. (CT) for their identification utilizing the technique of thin layer chromatography (TLC). Shankhpushpi is vigorously advertised for its effects on learning and memory in print and electronic media in India. Various phytoconstituents have been reported in these herbs namely, p-coumaryl derivatives, xanthones, anthocyanins and flavonones. We explored the two ...

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